Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
447
datasets available to search
ShareScore release 0.9.0
Dataset results
447 results for “peripheral blood mononuclear cells”
Backpain exercise therapy remodels human epigenetic profiles in buccal and human peripheral blood mononuclear cells: An exploratory study in young male participants
<pre><strong>###### Files description #####</strong><br> <strong>Notes</strong>. 1) "BT" refers to before therapy and "AT" to after therapy. 2) 0 refers to FALSE and 1 to TRUE for binary variables. The provided files have tab-separated columns except the .RDS which is and R output of the mixOmics DIABLO integration analysis. <strong># Questionnaire</strong> > participants_categories.tsv: per participant (rows), output of the clustering with the participant ("ID") category ("category") per class<br> ("class") > questionnaire_agility_metrics.tsv: questionnaire and agility metrics per participant (rows) for the participants ("ID") with at least one paired AT+BT data in one type of biological sample (indicated in the columns "swab", "PBMC", and "plasma") <strong># PTMs</strong> Samples´ names are encoded as PBMC_AT_8_batch1, i.e. cells origin_time upon therapy_ID_batch (we removed _batch column suffix for the <br>processed files). NA indicates an undetected intensity. > raw_PBMC_light_labelled_intensities.tsv: raw intensity of light/endogenous peptides (row) by precursor per sample (column) from PBMC > raw_swab_light_labelled_intensities.tsv: idem from buccal cells > raw_PBMC_heavy_labelled_intensities.tsv: raw intensity of light/endogenous peptides (row) by precursor per sample (column) from PBMC > raw_swab_heavy_labelled_intensities.tsv: idem from buccal cells > raw_PBMC_heavynormalized_intensities.tsv: raw intensity of light peptides normalized by heavy peptides intensity (row) by precursor per <br>sample (column) > raw_swab_heavynormalized_labelled_intensities.tsv: idem from buccal cells > processed_cleaned_PBMC_log2intensities.tsv: processed (heavy normalized, imputed, batch-corrected) intensity of peptides aggregated by modification (PTM, row) by precursor per sample (column) after log2-transformation. The relative abundances are computed from this file. Rows without me/ac suffix represents the amount of unmodified peptide for the considered site. > processed_cleaned_swab_log2intensities.tsv: idem from buccal cells > rel_abundance_PTM_PBMC.tsv: relative abundance computed per precursor, e.g. for a given sample, the H3_K4+H3_K4me1+H3_K4me2+H3_K4me3 <br>relative abundance values must sum to 100, with the relative abundance of H3_K4 representing the absence of modified K4. > rel_abundance_PTM_swab.tsv: idem from buccal cells > tests_from_rel_abundance_PTM_swab_PBMC.tsv: per type of samples ("Sample.origin", i.e.swab of PBMC) and per PTM (rows, "PTM"), report <br>the output of classic (p-values, adjusted with Benjamini-Hochberg (BH), or Benjamini-Yekutieli procedure (BY), from raw and arcsin square <br>root transformed percentage) and PLS-DA tests (VIP - Variable Importance score - and its 95% confidence interval). The percentage of change<br>of each PTM after therapy relative tobefore therapy is reported in "perc_change.AT.over.BT" column. The "is_candidate" indicates if the PTM has been considered as a hit in the swab or PBMC. <strong># Plasma</strong> Samples´ names are encoded as PLASMA_AT_8_batch1, i.e. cells origin_time upon therapy_ID_batch. NA indicates an undetected intensity. > raw_plasma_maxquant_log2ibaq_intensities.tsv: raw data from protein group MaxQuant file. The iBAQ columns are used in later steps. > processed_cleaned_plasma_log2intensities.tsv: processed (imputed, batch-corrected) intensity of protein groups after log2-transformation. > tests_from_intens_plasma.tsv: per protein group ("Proteins.ID"), report the output of classic (p-values, adjusted Benjamini-Hochberg (BH),<br>or Benjamini-Yekutieli procedure (BY), from log2-transformed intensities) and PLS-DA tests (VIP and its 95% confidence interval). The log2 <br>fold change after therapy relative to before therapy is reported in "log2FC.AT.over.BT" column. The "is_candidate" indicates if the protein group has been considered as a hit. <strong># Integration</strong> > circos_input: output of DIABLO analysis with correlation threshold set to 0.7. Use the readRDS R function to open.</pre> <p> </p>
Transcriptional profiling of peripheral blood mononuclear cells identifies inflammatory phenotypes in ataxia telangiectasia
<p>This is an AnnData object in h5ad (hdf5) format containing de-identified bulk RNA-seq gene expression matrices from PBMCs. These data are related to the study entitled "Transcriptional profiling of peripheral blood mononuclear cells identifies inflammatory phenotypes in ataxia telangiectasia". </p><p>This AnnData object contains a table of sample-specific metadata (`obs`), gene-specific metadata (`var`), and multiple gene expression matrices stored as `layers`. These layers include raw counts, DEseq2 normalized counts, vst normalized counts, and rlog normalized counts. Some additional layers include regressed versions of the previously mentioned counts matrices, where sequencing batch (`cohort` in the obs table) has been regressed out using the `combat` tool. The layer `rlog_combat_regressed_batch` is recommended for downstream processing, and has been loaded into the `X` slot of the anndata object for convenience. </p><p>The md5sum of this h5ad file is listed here: 04d7c6c549fb37cf730a5dca7897f86f</p><p>Opening and working with AnnData objects in h5ad format requires the use of the `anndata` python library (https://github.com/scverse/anndata). </p>
Endogenous plasma resuspension of peripheral blood mononuclear cells prevents preparative-associated stress that modifies polyA-enriched RNA responses to subsequent acute stressors
<p>This dataset is for a 2024 manuscript by Dongyang Li<sup>1,2</sup>, Karina Al-Dahleh<sup>1</sup>, Daniel A. Murphy<sup>3</sup>, Sonya Georgieva<sup>1</sup><em>,</em> Nik Matthews<sup>4</sup>, and Claire L. Shovlin<sup>1,2,5*</sup><strong> </strong>from the <sup>1</sup>National Heart and Lung Institute, Imperial College London, UK; <sup>2 </sup>National Institute for Health Research (NIHR) Imperial Biomedical Research Centre, London, W2 1NY UK; <sup>3</sup>Pharmacy, Imperial College Healthcare NHS Trust; London, W12 OHS, UK ; <sup>4</sup> NIHR Genomic Facility, Faculty of Medicine, Imperial College London; <sup>5</sup> Specialist Medicine, Imperial College Healthcare NHS Trust; London, W12 OHS, UK. </p>
Establish Tolerance In MS With Peptide-Coupled, Peripheral Blood Mononuclear Cells
ClinicalTrials.gov study NCT01414634. IPD Sharing: Not stated. Countries: 0. Publications: 1.
Peripheral Blood Mononuclear Cell (PBMC) Gene Expression in HCV Genotype 1 Patients
ClinicalTrials.gov study NCT00680173. IPD Sharing: Not stated. Countries: 1. Publications: 4.
The Effects of Crocin Supplementation on Metabolic Parameters, Oxidative Stress, AMP- Activated Protein Kinase and Inflammation-promoting Genes Expression in Peripheral Blood Mononuclear Cells in Pati
ClinicalTrials.gov study NCT04163757. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Apheresis and Specimen Collection Procedures to Obtain Plasma, Peripheral Blood Mononuclear Cells (PBMCs) and Other Specimens for Research Studies
ClinicalTrials.gov study NCT00067054. IPD Sharing: Not stated. Countries: 2. Publications: 4.
Decitabine Combining Modified CAG Followed by HLA Haploidentical Peripheral Blood Mononuclear Cells Infusion for Elderly Patients With Acute Myeloid Leukemia(AML）
ClinicalTrials.gov study NCT01690507. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Immunoprofilling of Peripheral Blood Mononuclear Cells in Children With Attention Deficit/Hyperactivity Disorder
ClinicalTrials.gov study NCT06109337. IPD Sharing: NO. Countries: 1. Publications: 2.
Dietary Intervention Replacing Carbohydrate With Protein and Fat Has Greater Effect on Peripheral Blood Mononuclear Cell Metabolites Than on Plasma Metabolites in Patients With Prediabetes or Type-2 D
ClinicalTrials.gov study NCT02191644. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Purified CD34+ Cells Versus Peripheral Blood Mononuclear Cells in Treatment of Critical Limb Ischemia
ClinicalTrials.gov study NCT02089828. IPD Sharing: Not stated. Countries: 1. Publications: 4.
Recruitment and Apheresis Collection of Peripheral Blood Hematopoietic Stem Cells, Mononuclear Cells and Granulocytes
ClinicalTrials.gov study NCT00001405. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Data from: Bulk-seq results from peripheral blood mononuclear cells (PBMCs) of VKH patients and proteomic profiling of shAPOE-transduced HMC3 cells were employed to uncover potential downstream targets of APOE
Open the record for dataset details and reuse information.
Peripheral mononuclear blood cell apheresis in a preclinical ovine model
<p>Dataset relating to sheep blood values</p>
Effect of Entecavir Versus Tenofovir on HBV DNA Level in Peripheral Blood Mononuclear Cells
ClinicalTrials.gov study NCT05168293. IPD Sharing: Not stated. Countries: 0. Publications: 22.
Effects of Ginger Supplementation on NF-KB in Peripheral Blood Mononuclear Cells in Type 2 Diabetes Mellitus
ClinicalTrials.gov study NCT02666807. IPD Sharing: UNDECIDED. Countries: 0. Publications: 4.
Expression of Toll-like Receptors 3 , 7 and 9 in Peripheral Blood Mononuclear Cells of COVID-19 Patients
ClinicalTrials.gov study NCT05089110. IPD Sharing: Not stated. Countries: 0. Publications: 2.
Autologous Peripheral Blood Mononuclear Cells in Diabetic Foot Patients With No-option Critical Limb Ischemia
ClinicalTrials.gov study NCT04255004. IPD Sharing: NO. Countries: 0. Publications: 42.
Transcriptome profiling of peripheral blood mononuclear cells from highly susceptible adult cattle infected with a virulent strain of Babesia bovis
GEO Series GSE299675. Bos taurus. 8 samples. Type: Expression profiling by high throughput sequencing.
Single-Cell RNA Sequencing of Peripheral Blood Mononuclear Cells From Acute Myocardial Infarction
GEO Series GSE269269. Homo sapiens. 10 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.