Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
38
datasets available to search
ShareScore release 0.9.0
Dataset results
38 results for “pleura”
FIG 3. Scanning electron micrographs for Chimairacoris lakshmiae. A. Head, left ventrolateral view. B. Thoracic pleura, left lateral view. C. Profemur. D, E. Pretarsus. F in A Remarkable New Genus and New Species of the Plant Bug (Heteroptera: Miridae: Phylinae), Inhabiting Psyllid Leaf Margin Roll Gall on Indian Banyan, Ficus benghalensis
FIG 3. Scanning electron micrographs for Chimairacoris lakshmiae. A. Head, left ventrolateral view. B. Thoracic pleura, left lateral view. C. Profemur. D, E. Pretarsus. F. Male abdomen (sternum).
Fig. 119. Pleura. A in Revision of the Nearctic species of the Lasioglossum (Dialictus) gemmatum species complex (Hymenoptera: Halictidae)
Fig. 119. Pleura. A. Lasioglossum lepidii (Graenicher, 1927), ♂, preëpisternum and hypoepimeron more finely punctate than mesepisternum. B. L. diabolicum sp. nov., ♂, preëpisternum and hypoepimeron as coarsely punctate as mesepisternum. Scale bars = 0.5 mm.
Data from 90-day quantitative inhalation toxicology study evaluating the dose-response and fate in the lung and pleura of chrysotile-containing brake dust
<p>The final results from this multi-dose, 90-day inhalation toxicology study in the rat with life-time post-exposure observation have shown a significant fundamental difference in pathological response and tumorgenicity between brake dust generated from brake pads manufactured with chrysotile or from chrysotile alone in comparison to the amphiboles, crocidolite and amosite asbestos.</p> <p>The groups exposed to brake dust showed no significant pathological or tumorigenic response in the respiratory track compared to the air control group at exposure concentrations and deposited doses well above those at which humans have been exposed. Slight alveolar/interstitial macrophage accumulation of particles was noted. Wagner grades were 1–2 (1 = control group), similar to the TiO2 particle control group. Chrysotile was not biopersistent, exhibiting in the lung a deterioration of its matrix which results in breakage into particles and short fibers which can be cleared by alveolar macrophages and which can continue to dissolve. Particle-laden macrophage accumulation was observed, leading to a very-slight interstitial inflammatory response (Wagner grade 1–3). There was no peribronchiolar inflammation, occasional very-slight interstitial fibrosis (Wagner grade 4), and no exposure-related tumorigenic response.</p> <p>The pathological response of crocidolite and amosite compared to the brake dust and chrysotile was clearly differentiated by the histopathology and the confocal analysis. Crocidolite and amosite induced persistent inflammation, microgranulomas, persistent fibrosis (Wagner grades 4), and a dose-related lung tumor response. Confocal microscopy quantified extensive inflammatory response and collagen development in the lung, visceral and parietal pleura as well as pleural adhesions.</p> <p>These results provide a clear foundation for differentiating the innocuous effects of brake dust exposure from the adverse effects following amphibole asbestos exposure.</p>
3D co-culture of pleura
<p>Pleural mesothelial cells are the predominant cell type in the pleural cavity, but their role in the pathogenesis of pleural diseases needs to be further elucidated. 3D organotypic models are a encouraging approach for an <em>in vivo</em> understanding of molecular disease development. The aim of the present study was to develop a 3D organotypic model of the pleural mesothelium. Specimens of human <em>pleura parietalis</em> were obtained from patients undergoing surgery at the University Hospital Leipzig, Germany. 3D co-culture model of pleura was established from human pleural mesothelial cells and fibroblasts. The model was compared to human pleura tissue by phase-contrast and light microscopy, immunochemistry and -fluorescence as well as solute permeation test. Histological assessment of the 3D co-culture model displayed the presence of both cell types mimicking the morphology of the human pleura. Vimentin and Cytokeratin, PHD1 showed a similar expression pattern in pleural biopsies and 3D model. Expression of Ki-67 indicates the presence of proliferating cells. Tight junctional marker ZO-1 was found localized at contact zones between mesothelial cells. Each of these markers were expressed in both the 3D co-culture model and human biopsies. Permeability of 3D organotypic co-culture model of pleura was found to be higher for 70 kDa-Dextran and no significant difference was seen in the permeability for small dextran (4kDa). In summary, the presented 3D organoid of pleura functions as a robust assay for pleural research serving as a precise reproduction of the <em>in vivo</em> morphology and microenvironment.</p>
Adjuvant Tumor Lysate Vaccine and Iscomatrix With or Without Metronomic Oral Cyclophosphamide and Celecoxib in Patients With Malignancies Involving Lungs, Esophagus, Pleura, or Mediastinum
ClinicalTrials.gov study NCT02054104. IPD Sharing: NO. Countries: 1. Publications: 4.
Data from 90-day quantitative inhalation toxicology study evaluating the dose-response and fate in the lung and pleura of chrysotile-containing brake dust
Open the record for dataset details and reuse information.
FIGURE 1. Pleura, lateral view. A in The genus Manota Williston (Diptera: Mycetophilidae) in Melanesia and Oceania
FIGURE 1. Pleura, lateral view. A. Manota serawei sp. n. (holotype). B. M. explicans sp. n. (paratype). C. M. perissochaeta sp. n. (paratype). D. M. spathula sp. n. (holotype). E. M. bicuspis sp. n. (paratype). Scale 0.10 mm.
Epidemiology and Outcome of Solitary Fibrous Tumors of the Pleura.
ClinicalTrials.gov study NCT01694654. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Depsipeptide/Flavopiridol Infusion for Cancers of the Lungs, Esophagus, Pleura, Thymus or Mediastinum
ClinicalTrials.gov study NCT00094978. IPD Sharing: Not stated. Countries: 1. Publications: 3.
S9810: Gemcitabine Plus Cisplatin in Treating Patients With Malignant Mesothelioma of the Pleura That Cannot Be Removed by Surgery
ClinicalTrials.gov study NCT00003723. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Pilot Study of Allogeneic Tumor Cell Vaccine With Metronomic Oral Cyclophosphamide and Celecoxib in Patients Undergoing Resection of Lung and Esophageal Cancers, Thymic Neoplasms, and Malignant Pleura
ClinicalTrials.gov study NCT01143545. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Pleurectomy/Decortication (Neo) Adjuvant Chemotherapy and Intensity Modulated Radiation Therapy to the Pleura in Patients With Locally Advanced Malignant Pleural Mesothelioma
ClinicalTrials.gov study NCT00715611. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Decitabine in Treating Patients With Unresectable Lung or Esophageal Cancer or Malignant Mesothelioma of the Pleura
ClinicalTrials.gov study NCT00019825. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Cisplatin With or Without Raltitrexed in Treating Patients With Malignant Mesothelioma of the Pleura
ClinicalTrials.gov study NCT00004920. IPD Sharing: Not stated. Countries: 11. Publications: 4.
Mid-point Transverse Process to Pleura Block Versus Thoracic Paravertebral Block in Posterolateral Thoracotomy
ClinicalTrials.gov study NCT06361121. IPD Sharing: NO. Countries: 1. Publications: 4.
Tumor Cell Vaccine for Patients Undergoing Surgery for Sarcomas, Melanomas, Germ Cell Tumors, or Malignancies That Have Metastasized to the Lungs, Pleura, or Mediastinum
ClinicalTrials.gov study NCT01313429. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Ultrasound-guided Paravertebral Block Versus Mid-point Transverse Process Pleura Block in Mastectomy Surgery
ClinicalTrials.gov study NCT05332028. IPD Sharing: NO. Countries: 1. Publications: 8.
Ultrasound-guided Biopsy of the Pleura as a Supplement to Extraction of Fluid in Patients With One-sided Fluid in the Pleura
ClinicalTrials.gov study NCT04236037. IPD Sharing: NO. Countries: 1. Publications: 1.
Fig. 103. Pleura. A in Revision of the Nearctic species of the Lasioglossum (Dialictus) gemmatum species complex (Hymenoptera: Halictidae)
Fig. 103. Pleura. A. Lasioglossum gaudiale (Sandhouse, 1924), ♂, with sparse tomentum not obscuring the surface. B. L. gloriosum sp. nov., ♂, with dense tomentum obscuring the surface on preëpisternum and metepisternum. Scale bars = 0.5 mm.
Mini Invasive Endomicroscopy of the Pleura for Malignancies Diagnosis
ClinicalTrials.gov study NCT04731129. IPD Sharing: NO. Countries: 1. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.