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8
datasets available to search
ShareScore release 0.9.0
Dataset results
8 results for “potency data”
Data from: Spider venom potency exhibits phylogenetic prey-specificity but does not trade-off with body size or silk use in prey capture
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Data from: Significant differences in capsid properties and potency between AAV vectors produced in Sf9 and HEK293 cells
<p>For successful vector-based gene therapy manufacturing, the selected adeno-associated virus (AAV) vector production system must produce vector at sufficient scale. However, concerns have arisen regarding the quality of vector produced using different systems. In this study, we compared AAV serotypes 1, 8, and 9 produced by two different systems (Sf9/baculovirus and HEK293/transfection) and purified by two separate processes. We evaluated capsid properties including protein composition, post-translational modification, particle content profiles, and in vitro and in vivo vector potency. Vectors produced in the Sf9/baculovirus system displayed reduced incorporation of viral protein 1 and 2 into the capsid, increased capsid protein deamidation, increased empty and partially packaged particles in vector preparations, and an overall reduced potency. The differences observed were largely independent of the harvest method and purification process. These findings illustrate the need for careful consideration when choosing an AAV vector production system for clinical production.</p>
Data from: Significant differences in capsid properties and potency between AAV vectors produced in Sf9 and HEK293 cells
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Dataset: Chromatographic data for publication Exploration and optimisation of structure-activity relationships of newtriazole-based C-terminal Hsp90 inhibitors towards in vivoanticancer potency
<p>Bio-chromoatographic data caming from publication Exploration and optimisation of structure-activity relationships of new triazole-based C-terminal Hsp90 inhibitors towards in vivo anticancer potency</p>
Data from: Advances in neglected tropical disease vaccines: developing relative potency and functional assays for the Na-GST-1/Alhydrogel hookworm vaccine
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In vitro transcriptomic analyses reveal pathway perturbations, estrogenic activities, and potencies of data-poor BPA alternative chemicals
GEO Series GSE211183. Homo sapiens; synthetic construct. 768 samples. Type: Expression profiling by high throughput sequencing.
NCP26 is a potent prolyl-tRNA synthetase inhibitor and induces pro- apoptotic responses with in vivo potency in multiple myeloma. Single-cell RNA-seq data BM samples.
GEO Series GSE186447. Homo sapiens. 26 samples. Type: Expression profiling by high throughput sequencing.
NCP26 is a potent prolyl-tRNA synthetase inhibitor and induces pro- apoptotic responses with in vivo potency in multiple myeloma. Bulk RNA-seq data.
GEO Series GSE186445. Homo sapiens. 66 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.