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31 results for “prefrontal activity”
Prefrontal cortex activation and functional connectivity during human male orgasm measured with fNIRS
<p>A portable fNIRS system Brite MKII (Artinis, NE) was placed on the PFC of the self-experimenting participant (Male, 43 years). Ten sources and eight detectors are combined into 22 long separation channels (30mm) and two short-separation channels (SSC) to cover the PFC (Figure 1A). The experiment lasted 392s where the participant was subject to pornographic video clips (V) and performed genital self-stimulation (M) until orgasm was reached (O).<br>Citation of the article related to this dataset:</p> <div> <div><strong>Guevara, E.</strong> (2024). <em>Prefrontal cortex activation and functional connectivity during human male orgasm measured with fNIRS</em> [Preprint]. OSF. <a href="https://doi.org/10.31219/osf.io/6y2ze">https://doi.org/10.31219/osf.io/6y2ze</a></div> </div>
Transcranial direct current stimulation (tDCS) over the left prefrontal cortex does not affect time-trial self-paced cycling performance: Evidence from oscillatory brain activity and power output.
<p>This research will shed new light into the bidirectional relationship between acute aerobic exercise, brain and cognition. This is based on the particular role of executive (cognitive) function during exercise. The rationale of our study is that stimulation of the prefrontal cortex that has been repeatedly associated with executive function, would facilitate or impair self-paced aerobic exercise. This would also affect cognitive performance immediately after exercise. We will use a modified flanker’s task as a form of assessing executive function (see below for further details). The flanker’s task implies two different stimuli, one congruent and one incongruent. Relative to “congruent” stimuli, these “incongruent” stimuli are usually accompanied by increased response times (RTs) and decreased accuracy. To stimulate the prefrontal cortex, we use transcranial direct-current stimulation (tDCS). tDCS is able to induce cortical changes by hyperpolarizing (anodal) or depolarizing (cathodal) neuron’s resting membrane potential.<br> Therefore, the hypotheses of this research are:<br> 1) Anodal stimulation (relative to sham and cathodal stimulation) will improve self-paced aerobic exercise and, consequently it will also improve subsequent cognitive performance.<br> 2) Cathodal stimulation (relative to sham and anodal stimulation) will impair self-paced aerobic exercise and subsequent cognitive performance.<br> </p>
Layer-dependent activity in human prefrontal cortex during working memory
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A Prefrontal Cortex Map based on Single Neuron Activity
<p>Intermediate results files (after preprocessing) to recreate the figures from:</p> <p><em><strong>A Prefrontal Cortex Map based on Single Neuron Activity, </strong></em>Pierre Le Merre*, Katharina Heining*<em>, Marina Slashcheva, Felix Jung, Eleni Moysiadou, Nicolas Guyon, Ram Yahya, Hyunsoo Park, Fredrik Wernstal, and </em><em>Marie </em><em>Carlén.</em> Equal contribution.</p> <p>Article currently available at: https://www.biorxiv.org/content/10.1101/2024.11.06.622308v2</p> <p>The raw data can be found at: https://dandiarchive.org/dandiset/001260?pos=1</p> <p>Description: Brain-wide high-density extracellular recordings (Neuropixels) in head-fixed mice during distinct passive listening and auditory behavioral tasks. About half of the recordings are in the prefrontal cortex (PFC) and half from other brain regions (3 cortical and 10 subcortical). In PFC we include 11 subregions: secondary motor area (MOs), anterior cingulate area – dorsal and ventral part (ACAd, ACAv), prelimbic area (PL), infralimbic area (ILA), orbital area – medial, lateral, and ventrolateral part (ORBm, ORBvl, ORBl), agranular insular area – dorsal and ventral part (AId, AIv), and frontal pole (FRP).</p> <p>The code generating these intermediate files from the raw data can be found at: https://github.com/hejDMC/pfcmap</p> <p> </p>
Medial prefrontal cortex and anteromedial thalamus interaction regulates motivation related behavior and dopaminergic neuron activity: Animal Behavior
<p>The excel Source DATA file contains the data described in Figures 2c, 2d, 2f, and 3b and Supplementary Figure 3b and 3c. The fiber photometry data described in Supplementary Figure 9 are found in the CSV files. The CSV file names reflect animal IDs. </p>
Activity in developing prefrontal cortex is shaped by sleep and sensory experience
<p>In developing rats, behavioral state exerts a profound modulatory influence on neural activity throughout the sensorimotor system, including primary motor cortex (M1). We hypothesized that similar state-dependent modulation occurs in prefrontal cortical areas with which M1 forms functional connections. Here, using 8- and 12-day-old rats cycling freely between sleep and wake, we record neural activity in M1, secondary motor cortex (M2), and medial prefrontal cortex (mPFC). At both ages in all three areas, neural activity increased during active sleep (AS) compared with wake. Also, regardless of behavioral state, neural activity in all three areas increased during periods when limbs were moving. The movement-related activity in M2 and mPFC, like that in M1, is driven by sensory feedback. Our results, which diverge from those of previous studies using anesthetized pups, demonstrate that AS-dependent modulation and sensory responsivity extend to prefrontal cortex. These findings expand the range of possible factors shaping the activity-dependent development of higher-order cortical areas.</p>
Long-range inhibition synchronizes and updates prefrontal task activity
<p>Trial-by-trial physiology data (synchrony measurements and population activity vectors used to compute population vector similarity) supporting Cho et al., 2023. Any use of this data should cite this DOI as well as the associated publication.</p>
Study to Evaluate Armodafinil Treatment in Improving Prefrontal Cortical Activation and Working Memory Performance
ClinicalTrials.gov study NCT00711516. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Activity in developing prefrontal cortex is shaped by sleep and sensory experience
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Electrophysiological recordings of prefrontal activity over learning in non-human primates
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Medial prefrontal cortex and anteromedial thalamus interaction regulates motivation related behavior and dopaminergic neuron activity: fMRI: Rats
<p>Rat fMRI activation images supplementing for Fig. 3d and Suppl. Fig. 5.</p>
Medial prefrontal cortex and anteromedial thalamus interaction regulates motivation related behavior and dopaminergic neuron activity: fMRI: Human
<p>Human fMRI activation images supplementing for Fig. 8 and Suppl. Fig. 11.</p>
The Effects of MDMA on Prefrontal and Amygdala Activation in PTSD.
ClinicalTrials.gov study NCT03752918. IPD Sharing: NO. Countries: 1. Publications: 39.
Attentional Focus and Prefrontal Cortical Activation in Older Adults and Patients With Parkinson's Disease (PD)
ClinicalTrials.gov study NCT05073874. IPD Sharing: Not stated. Countries: 1. Publications: 17.
The Role of Dopamine, Reward Learning and Prefrontal Activity in Expectation-induced Mood Enhancement
ClinicalTrials.gov study NCT05208294. IPD Sharing: YES. Countries: 1. Publications: 0.
Multicenter Comparative Study of the Activity of the Medial Prefrontal Cortex in Vulnerability to Depression
ClinicalTrials.gov study NCT02171923. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Attentional Focus and Prefrontal Cortical Activation
ClinicalTrials.gov study NCT04757844. IPD Sharing: NO. Countries: 1. Publications: 13.
Study of Emotional Regulation and Underlying Prefrontal Activity in Binge Eating Disorder
ClinicalTrials.gov study NCT06864065. IPD Sharing: NO. Countries: 1. Publications: 3.
Theta Phase-specific TMS to Modulate Prefrontal Activity
ClinicalTrials.gov study NCT05416138. IPD Sharing: YES. Countries: 1. Publications: 0.
Gut microbiota modualtes innate anxiety via the neuron activity of medial prefrontal cortex in mice
GEO Series GSE290997. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.