Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
26
datasets available to search
ShareScore release 0.9.0
Dataset results
26 results for “preoptic area”
Fig. 1 in Glyphosate commercial formulation effects on preoptic area and hypothalamus of Cardinal Neon Paracheirodon axelrodi (Characiformes: Characidae)
Fig. 1. Cross-section of preoptic area (AP) and posterior diencephalic region (PDR) of Paracheirodon axelrodi showing its different neuronal nuclei. a. Panoramic view of AP showing different neuronal nuclei. b. Panoramic view of PDR, including HT neuronal nuclei. Technique: high resolution optical microscopy (HROM) Bar 100 μm.
Data from: An evolutionary loss of parental care in stickleback is associated with differences in the activity, but not the number, of neuropeptidergic neurons in the preoptic area
Open the record for dataset details and reuse information.
Neurogliaform cortical interneurons derive from cells in the preoptic area
<p>Excel document containing the raw dataset used in each figures and links to morphology reconstructions</p>
Data accompanying The preoptic area and dorsal habenula jointly support homeostatic navigation in larval zebrafish
<p>"<strong>The preoptic area and dorsal habenula jointly support homeostatic navigation in larval zebrafish"</strong></p><p>This repository contains the data presented in Palieri et al, 2023 (preprint <a href="https://www.biorxiv.org/content/10.1101/2023.05.18.541289v1">https://www.biorxiv.org/content/10.1101/2023.05.18.541289v1</a> ).</p><p>The data is organized into the following subfolders:</p><ul><li><strong>Behavior</strong>: This folder contains all the data related to freely swimming experiments, including both spatial (spatial_gradient subfolder) and temporal (temporal_gradient subfolder) temperature gradients. The former also includes data from chemogenetic and 2-photon mediated ablations.</li><li><strong>Imaging</strong>: Within this folder, you will find data obtained through confocal microscopy (in the confocal subfolder) and lightsheet microscopy (in the lightsheet subfolder). Confocal imaging was used to verify proper habenula ablation (dHb_preablation and dHb_postablation). Lightsheet imaging was performed for functional calcium imaging experiments during temperature and salinity gradients. The lightsheet subfolder is further subdivided into long and short experiments, with each fish having its own dedicated folder. Inside each fish's folder, you can access imaging data (traces, local coordinates, coordinates in reference space, along with relevant indexes such as the reliability index) and behavioral data (acquired using the Stytra software).</li></ul><p>Please contact Ruben Portugues for further information.</p>
Data for: Microglia phagocytosis determines the volume and function of the rat Sexually Dimorphic Nucleus of the Preoptic Area
<p>The Sexually Dimorphic Nucleus of the Preoptic Area (SDN-POA) is the oldest and most robust sex difference reported in mammalian brain and is singular for its presence across a wide range of species from rodents to ungulates to man. This small collection of Nissl dense neurons is reliably larger in volume in males. Yet, despite its notoriety and intense interrogation, both the mechanism establishing the sex difference and the functional role of the SDN have remained elusive. Convergent evidence from rodent studies led to the conclusion that testicular androgens aromatized to estrogens are neuroprotective in males and that higher apoptosis (naturally occurring cell death) in females determines their smaller SDN. In several species, including humans, a smaller SDN correlates with a preference for mating with males. We report here that this volume difference is dependent upon a participatory role of phagocytic microglia which engulf more neurons in the female SDN and assure their destruction . Selectively blocking microglia phagocytosis temporarily spared neurons from apoptotic death and increased SDN volume in females without hormone treatment. Increasing the number of neurons in the SDN in neonatal females resulted in loss of preference for male odors in adulthood, an effect paralleled by dampened excitation of SDN neurons as evidenced by reduced IEG expression when exposed to male urine. Thus, the mechanism establishing a sex difference in SDN volume includes an essential role for microglia, and SDN function as a regulator of sexual partner preference is confirmed.</p>
Data for: Microglia phagocytosis determines the volume and function of the rat Sexually Dimorphic Nucleus of the Preoptic Area
Open the record for dataset details and reuse information.
Fig. 2 in Glyphosate commercial formulation effects on preoptic area and hypothalamus of Cardinal Neon Paracheirodon axelrodi (Characiformes: Characidae)
Fig. 2. Cross-sections of preoptic area (AP) of Paracheirodon axelrodi for different treatments with Roundup ActivoẈ. MC cells are present at different AP nuclei in all treatments. Mid dorsal telencephalic nucleus (MD). Anterior preoptic parvocelular nucleus (PPa). Lateral dorsal telencephalic nucleus (LD). Adjacent blood vessels (AV) and internal blood vessels (IV) are shown. MC cells are shown by black arrows. Technique: high resolution optical microscopy (HROM). Bar 25 μm.
Fig. 4 in Glyphosate commercial formulation effects on preoptic area and hypothalamus of Cardinal Neon Paracheirodon axelrodi (Characiformes: Characidae)
Fig. 4. Number of AP and PDR parenchyma MC cells found for each one of Roundup ActivoẈ treatments. Each value represents mean ± SD. Different letters correspond to significant differences (P<0.05 values). The treatments are in units of mg / L. N= 3.
Fig. 3 in Glyphosate commercial formulation effects on preoptic area and hypothalamus of Cardinal Neon Paracheirodon axelrodi (Characiformes: Characidae)
Fig. 3. Cross-sections of posterior diencephalic region (PDR) of Paracheirodon axelrodi for different treatments with Roundup ActivoẈ. MC cells were found at different neuronal nuclei of posterior diencephalic area (PDR) in all treatments. Optic Tectum (TeO), gray periventricular area of optic tectum (PGZ), Torus semicircularis (TS), Torus lateralis (TLa), Hypothalamus with ventral are of periventricular hypothalamus (Hv) and anterior tuberal nucleus (ATN). Adjacent blood vessels (AV), internal blood vessels (IV), nerve (N). MC cells are shown by black arrows. Technique: high resolution optical microscopy (HROM). Bar 25 µm.
Homeostatic regulation of REM sleep by the preoptic area of the hypothalamus
Open the record for dataset details and reuse information.
Data from: Understanding the loss of maternal care in avian brood parasites using preoptic area transcriptome comparisons in brood parasitic and non-parasitic blackbirds
Open the record for dataset details and reuse information.
Gene Expression Patterns in the Preoptic Area of Mice with Defective FGF Signaling in GnRH Neurons
GEO Series GSE285006. Mus musculus. 20 samples. Type: Expression profiling by high throughput sequencing.
Genetic markers for temperature-sensitive neurons in mouse preoptic area
GEO Series GSE126657. Mus musculus. 96 samples. Type: Expression profiling by high throughput sequencing.
Single nucleus RNA-seq of genetically labeled Esr1+ neurons from the bed nucleus of the stria terminalis (BNST), preoptic area (POA), ventromedial hypothalamus (VMH), and medial amygdala (MeA)
GEO Series GSE183093. Mus musculus. 14 samples. Type: Expression profiling by high throughput sequencing.
Prenatal Androgenization Alters the Development of GnRH Neuron and Preoptic Area RNA Transcripts in Female Mice (II)
GEO Series GSE162558. Mus musculus. 20 samples. Type: Expression profiling by high throughput sequencing.
Prenatal Androgenization Alters the Development of GnRH Neuron and Preoptic Area RNA Transcripts in Female Mice (I)
GEO Series GSE155314. Mus musculus. 48 samples. Type: Expression profiling by high throughput sequencing.
Bulk single nuclear sequencing in the ventral medial preoptic area
GEO Series GSE197547. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
DNMT inhibition in the Neonatal Preoptic Area
GEO Series GSE66203. Rattus norvegicus. 12 samples. Type: Expression profiling by high throughput sequencing.
Cellular evolution of the hypothalamic preoptic area of behaviorally divergent deer mice
GEO Series GSE272719. Peromyscus maniculatus; Peromyscus polionotus. 6 samples. Type: Expression profiling by high throughput sequencing.
Estrogen-Sensitive Medial Preoptic Area Neurons Coordinate Hypothermia and Hypometabolism in Mice
GEO Series GSE153350. Mus musculus. 7 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.