Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
35
datasets available to search
ShareScore release 0.9.0
Dataset results
35 results for “retrograde signalling”
The GENOMES UNCOUPLED1 protein has an ancient, highly conserved role but not in retrograde signalling
<p><span>The pentatricopeptide repeat protein GENOMES UNCOUPLED1 (GUN1) is required for chloroplast-to-nucleus signalling in response to plastid stress during chloroplast development in <em>Arabidopsis thaliana</em> but its exact molecular function remains unknown. Current data on GUN1 function is limited to <em>Arabidopsis</em>, so we set out to investigate the origin and evolution of the land plant GUN1 proteins. We retrieved GUN1 sequences from 76 phylogenetically diverse land plants and developed a GUN1 sequence profile using <em>hmmbuild</em> </span><span>(<a href="http://hmmer.org/">http://hmmer.org</a>)</span><span>. We then used this profile to systematically analyse the presence/absence of GUN1 sequences in transcriptomes from land plants and streptophyte algae. This dataset includes the GUN1 profile we developed, the code we used to analyse the results of screening over 500,000 PPR protein sequences with the profile, and an alignment of the 893 GUN1 sequences that we obtained.</span></p> <p><span>We used this data to show that GUN1 is an ancient protein that is highly conserved across land plants but missing from the <em>Rafflesiaceae</em> that lack chloroplast genomes. Our findings suggest that GUN1 is an ancient protein that evolved within the streptophyte algal ancestors of land plants before the first plants colonised land more than 470 million years ago. </span></p> <p><span>This dataset also includes transcript count data from an RNA-seq experiment looking at gene expression in liverwort <em>Marchantia polymorpha</em> wild type and <em>Mpgun1</em> mutant spore samples grown in the presence or absence of spectinomycin. We used this data to show that GUN1 does not act significantly in chloroplast retrograde signalling in the liverwort <em>M. polymorpha</em>. Its primary role is likely to be in chloroplast gene expression and its role in chloroplast retrograde signalling probably evolved more recently.</span></p>
Supplementary data from: Bimodal retrograde signaling disrupts a suppressor network and activates a key transcriptional activator to direct stress responses
Open the record for dataset details and reuse information.
The GENOMES UNCOUPLED1 protein has an ancient, highly conserved role but not in retrograde signalling
Open the record for dataset details and reuse information.
Retrograde bilin signaling enables Chlamydomonas greening and phototrophic survival
GEO Series GSE40031. Chlamydomonas reinhardtii. 16 samples. Type: Expression profiling by high throughput sequencing.
A Systems Approach for Decoding Mitochondrial Retrograde Signaling Pathways
GEO Series GSE27545. Homo sapiens. 17 samples. Type: Expression profiling by array.
Peroxisomal retrograde signaling in C. elegans
GEO Series GSE156318. Caenorhabditis elegans. 6 samples. Type: Expression profiling by high throughput sequencing.
TaSRO1 interacts with and suppresses TaSIP1 to fine tune mitochondrial retrograde signaling and enhance salinity stress tolerance
GEO Series GSE156679. Triticum aestivum. 12 samples. Type: Expression profiling by high throughput sequencing.
RNA Polymerase II read-through promotes expression of neighboring genes in SAL1-PAP-XRN retrograde signaling
GEO Series GSE115951. Arabidopsis thaliana. 21 samples. Type: Expression profiling by high throughput sequencing.
Maize cytolines provide key nuclear genes that are under the control of retrograde signaling pathways in plants
GEO Series GSE74096. Zea mays; Zea mays subsp. mays. 9 samples. Type: Expression profiling by array.
Mitochondrial TSPO Deficiency Triggers Retrograde Signaling in MA-10 Mouse Tumor Leydig Cells
GEO Series GSE164481. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Deconvoluting ACS1 retrograde signaling networks that regulate leaf development
GEO Series GSE152252. Arabidopsis thaliana. 18 samples. Type: Expression profiling by high throughput sequencing.
Retrograde mitochondrial signaling governs the identity and maturity of metabolic tissues
GEO Series GSE262023. Mus musculus. 46 samples. Type: Expression profiling by high throughput sequencing.
Mitochondrial retrograde signaling in mammals is mediated by the transcriptional cofactor GPS2 via direct mitochondria-to-nucleus translocation
GEO Series GSE80994. Mus musculus. 28 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Transcriptome response study of arabidopsis wild type (Col6-3), gun1-9 mutant and MORF2 overexpression lines to norflurazon treatment in retrograde signaling
GEO Series GSE110125. Arabidopsis thaliana. 10 samples. Type: Expression profiling by high throughput sequencing.
Mitochondrial retrograde signaling in mammals is mediated by the transcriptional cofactor GPS2 via direct mitochondria-to-nucleus translocation [ChIP-seq]
GEO Series GSE80992. Mus musculus. 20 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Mitochondrial retrograde signaling in mammals is mediated by the transcriptional cofactor GPS2 via direct mitochondria-to-nucleus translocation [GRO-seq]
GEO Series GSE80990. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
PSI photoinhibition alters iron homeostasis in chloroplasts and initiates retrograde signaling regulating nuclear gene expression
GEO Series GSE242125. Arabidopsis thaliana. 32 samples. Type: Expression profiling by high throughput sequencing.
MORF2 is a key effector of plastidial retrograde signaling for stress response and plant morphogenesis beyond RNA editing
GEO Series GSE213405. Arabidopsis thaliana. 10 samples. Type: Expression profiling by high throughput sequencing.
Scaling proprioceptor gene transcription by retrograde NT3 signaling
GEO Series GSE38074. Mus musculus. 39 samples. Type: Expression profiling by array.
Gene expression profiling of retrograde PAP-signaling and ABA-signaling mutants in response to ABA treatment
GEO Series GSE84997. Arabidopsis thaliana. 22 samples. Type: Expression profiling by array.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.