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28 results for “reversal learning”

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zenodo40/100

Data for "Reversal learning of visual cues in Heliconiini butterflies"

<p>Here I provide the data and R code used in the analyses included&nbsp;in the paper &quot;Reversal learning of visual cues in Heliconiini butterflies&quot;.</p>

opencc-by-4.0Jul 2023View details →
dryad40/100

Selective engagement of prefrontal VIP neurons in reversal learning

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publicJun 2025View details →
dryad36/100

Data from: Testing the greater male variability hypothesis: male mountain chickadees exhibit larger variation in reversal learning compared to females

The 'greater male variability hypothesis' predicts that males exhibit larger ranges of variation in cognitive performance compared to females, however, support for this hypothesis has come exclusively from studies of humans. This scenario aligns with the fact that the vast majority of the literature assessing sex differences in cognition is based on studies of humans and a few other mammals. In order to elucidate the underpinnings of cognitive variation and the potential for fitness consequences, we must investigate sex differences in cognition in non-mammalian systems as well. Here we assess the performance of male and female food-caching birds on a spatial learning and memory task and a reversal spatial task to address whether there are sex differences in mean cognitive performance or in the range of variation in performance. For both tasks, male and female mean performance was similar across four years of testing; however, males did exhibit a wider range of variation in performance on the reversal spatial task compared to females. The implications for mate choice and sexual selection of cognitive abilities are discussed, with a call for further investigation into sex-related cognitive variation.

opencc-zeroJul 2020View details →
zenodo36/100

Anonymized Dataset for "Towards a Better Understanding of Reverse-Complement Equivariance for Deep Learning Models in Genomics"

<p>Anonymous dataset for the paper&nbsp;&quot;Towards a Better Understanding of Reverse-Complement Equivariance for Deep Learning Models in Genomics.&quot; Includes data for simulated, binary prediction, and profile prediction tasks.&nbsp;</p>

opencc-by-4.0Jan 2021View details →
zenodo36/100

On the importance of additional behavioral observation in behavioral psychopharmacology research: a case study on agomelatine's effects on feedback sensitivity in probabilistic reversal learning test in rats (data&code)

<p>Dataset to the manuscript entitled:&nbsp;On the importance of additional behavioral observation in behavioral psychopharmacology research: a case study on agomelatine&#39;s effects on feedback sensitivity in probabilistic reversal learning test in rats.&nbsp;Code in R used for analysis data from probabilistic reversal learning (PRL) test performed in operant conditioning boxes. Script analyzes data files from MED-PC IV software.</p>

opencc-by-4.0Jun 2023View details →
dryad36/100

Tortoises develop and overcome position biases in a reversal learning task

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publicFeb 2019View details →
dryad36/100

Data from: Testing the greater male variability hypothesis: male mountain chickadees exhibit larger variation in reversal learning compared to females

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publicJul 2020View details →
dryad32/100

Data from: Brain size does not predict learning strategies in a serial reversal learning test

<p><span><span><span><span><span><span><span><span><span><span><span>Reversal learning assays are commonly used across a wide range of taxa to investigate associative learning and behavioural flexibility. In serial reversal learning, the reward contingency in a binary discrimination is reversed multiple times. Performance during serial reversal learning varies greatly at the interspecific level, as some animals adapt a rule-based strategy that enables them to switch quickly between reward contingencies. Enhanced learning ability and increased behavioural flexibility generated by a larger relative brain size has been proposed to be an important factor underlying this variation. Here we experimentally test this hypothesis at the intraspecific level. We use guppies (<i>Poecilia reticulata</i>) artificially selected for small and large relative brain size, with matching differences in neuron number, in a serial reversal learning assay. We tested 96 individuals over ten serial reversals and found that learning performance and memory were predicted by brain size, whereas differences in efficient learning strategies were not. We conclude that variation in brain size and neuron number is important for variation in learning performance and memory, but these differences are not great enough to cause the larger differences in efficient learning strategies observed at higher taxonomic levels. </span></span></span></span></span></span></span></span></span></span></span></p>

opencc-zeroJul 2020View details →
zenodo32/100

Data for paper "Information flow between motor cortex and striatum reverses during skill learning"

<p>Simultaneous spiking activity and local field potential (LFP) recordings from motor cortex (M1) and dorsolateral striatum (DLS) during learning of a reach-to grasp task.<br>Deposited data include spiking activity and LFP recordings, reaching trajectories, andi single-trial success data for the 8 animals included in the paper "Information flow between motor cortex and striatum reverses during skill learning".</p>

opencc-by-4.0Mar 2024View details →
dryad32/100

Data from: Reversal learning and neophobia test results in Chimango Caracaras

<p>In this study, we analyzed the variation in cognitive flexibility in the Chimango Caracara (<em>Milvago chimango</em>), across areas with different levels of urbanization. To assess this, we utilized the reversal learning assay which measures the ability to adapt behavior in response to changes in environmental contingencies. We also investigated the impact of neophobia on this variation. All chimangos studied succeeded in acquiring a color-reward association and reverting this learned association when the contingencies changed. Urban chimangos were faster than their rural and suburban counterparts during the initial discrimination and reversal phases. The reversal phase proved to be the most challenging task. The analysis of the errors made during this phase revealed that acquiring a new association (i.e., regressive errors) was challenging for the individuals studied, in comparison to inhibiting a previously learned one (i.e., perseverative errors). Neophobia was found to be lower in urban individuals compared to suburban and rural raptors. Moreover, neophobia showed a correlation with regressive errors during the reversal phase among rural and suburban chimangos, while no such correlation was observed among city-dwelling chimangos. We suggest that neophobia acted as a regulating factor of cognitive flexibility, mainly for individuals expressing relatively high levels of this personality trait.</p>

opencc-zeroMar 2024View details →
dryad32/100

Reversal learning in FTD (fMRI)

<p class="MsoNoSpacing"><b>Objective</b>: Frontotemporal Dementia (FTD) is a neurodegenerative disorder that results in disinhibition and difficulty with flexible responding when provided feedback. Inflexible responding is observed early in the course of the illness and contributes to the financial and social morbidities of FTD. Reversal learning is an established cognitive paradigm that indexes flexible responding in the face of feedback signaling a change in reinforcement contingencies, with components of reversal learning associated with specific neurotransmitter systems. The objective of the study was to evaluate the neural mechanisms underlying impaired flexible behavioural responding in FTD using a reversal learning paradigm combined with fMRI.</p> <p class="MsoNoSpacing"><b>Methods</b>: Twenty-two patients meeting the diagnostic criteria for FTD and twenty-one healthy controls completed the study. Participants completed an fMRI-adapted reversal learning task that indexes behavioural flexibility when provided positive and negative feedback.</p> <p class="MsoNoSpacing"><b>Results</b>: Patients with FTD demonstrated poorer behavioural flexibility relative to controls and abnormal BOLD responses within the left ventrolateral prefrontal cortex to incorrect responses made during the learning phase, and during correct responses when reward contingencies were reversed. As well, patients showed decreased activity within the left dorsal lateral prefrontal cortex to incorrect responses compared to controls.</p> <p class="MsoNoSpacing"><b>Conclusions</b>: These findings suggest that reversal learning impairments in patients with FTD, in particular those with frontal predominant atrophy, may be related to impaired flexible motor responding when selecting among several choices and deficient attention to relevant stimuli during instances of conflict (i.e. receiving negative feedback). These results and the associated neurotransmitter systems mediating these regions may provide targets for future pharmacological or behavioural interventions mediating these cognitive deficits.</p>

opencc-zeroJul 2021View details →
ClinicalTrials.gov32/100

Effects of Sativex(Registered Trademark) and Oral THC on Attention, Affect, Working Memory, Reversal Learning, Physiology and Brain Activation

ClinicalTrials.gov study NCT01037608. IPD Sharing: Not stated. Countries: 1. Publications: 3.

restrictedIPD-UNDECIDEDFeb 2026View details →
dryad32/100

Data from: Brain size does not predict learning strategies in a serial reversal learning test

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publicJul 2020View details →
dryad32/100

Data from: Reversal learning and neophobia test results in Chimango Caracaras

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publicApr 2024View details →
dryad32/100

Reversal learning in FTD (fMRI)

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publicJul 2021View details →
zenodo28/100

Data set for "Dynamic perceptual feature selectivity in primary somatosensory cortex upon reversal learning"

<p>This repository contains the data used to generate the figures and well as the main codes that were used for analyses.</p>

opencc-by-4.0Jun 2020View details →
dryad28/100

Data from: The quick are the dead: pheasants that are slow to reverse a learned association survive for longer in the wild

Cognitive abilities likely evolve through natural selection if they provide individuals with fitness benefits. A growing number of studies demonstrate a positive relationship between performance in psychometric tasks and (proxy) measures of fitness. We assayed the performance of 154 Common Pheasant Phasianus colchicus chicks on tests of acquisition and reversal learning, using a different set of chicks and different set of cue types (spatial location and colour) in each of two years and then followed their fates after release into the wild. Across all birds, individuals that were slow to reverse previously learned associations were more likely to survive to four months old. For heavy birds, individuals that rapidly acquired an association had improved survival to four months, whereas for light birds, slow acquirers were more likely to be alive. Slow reversers also exhibited less exploratory behaviour in assays when five weeks old. Fast acquirers visited more artificial feeders after release. By contrast to most other studies, we showed that apparently 'poor' cognitive performance (slow reversal speed suggesting low behavioural flexibility) correlates with fitness benefits in at least some circumstances. This correlation suggests a novel mechanism by which continued exaggeration of cognitive abilities may be constrained.

opencc-zeroDec 2017View details →
dryad28/100

Data from: Basic reversal-learning capacity in flies suggests rudiments of complex cognition

The most basic models of learning are reinforcement learning models (for instance, classical and operant conditioning) that posit a constant learning rate; however many animals change their learning rates with experience. This process is sometimes studied by reversing an existing association between cues and rewards, and measuring the rate of relearning. Augmented reversal-learning, where learning rates increase with practice, can be an important component of behavioral flexibility; and may provide insight into higher cognition. Previous studies of reversal-learning in Drosophila have not measured learning rates, but have tended to focus on measuring gross deficits in reversal-learning, as the ratio of two timepoints. These studies have uncovered a diversity of mechanisms underlying reversal-learning, but natural genetic variation in this trait has yet to be assessed. We conducted a reversal-learning regime on a diverse panel of Drosophila melanogaster genotypes. We found highly significant genetic variation in their baseline ability to learn. We also found that they have a consistent, and strong (1.3×), increase in their learning speed with reversal. We found no evidence, however, that there was genetic variation in their ability to increase their learning rates with experience. This may suggest that Drosophila have a hitherto unrecognized ability to integrate acquired information, and improve their decision making; but that their mechanisms for doing so are under strong constraints.

opencc-zeroDec 2016View details →
ClinicalTrials.gov28/100

FMRI Study of Performance During a Probabilistic Reversal Learning Task in Depression

ClinicalTrials.gov study NCT00075296. IPD Sharing: Not stated. Countries: 1. Publications: 1.

restrictedIPD-UNDECIDEDFeb 2026View details →
ClinicalTrials.gov28/100

Dopamine Receptor Contributions to Prediction Error and Reversal Learning in Anorexia Nervosa

ClinicalTrials.gov study NCT04128683. IPD Sharing: NO. Countries: 1. Publications: 0.

closedIPD-NOFeb 2026View details →

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Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record