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730
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730 results for “rhinitis”
Efficacy and safety of subcutaneous vs. sublingual immunotherapy in allergic rhinitis: a systematic review and meta-analysis
<p>Allergic rhinitis significantly impacts patients' quality of life, and allergen immunotherapy (AIT) offers an alternative to conventional treatments. This study compares the efficacy and safety of subcutaneous immunotherapy (SCIT) and sublingual immunotherapy (SLIT) for allergic rhinitis. A comprehensive search of PubMed, Embase, and ClinicalTrials.gov identified nine randomized controlled trials involving 780 patients (427 SCIT, 353 SLIT). The primary outcome was symptom score; secondary outcomes included medication score, symptom medication score, and local and systemic reactions. Results showed SCIT significantly reduced symptom scores compared to SLIT (Pooled SMD: -0.52, 95% CI: -0.60, -0.03, I2 =83%, P<0.05). However, SCIT patients experienced more severe systemic reactions (grade 3&4) than SLIT patients (Pooled SMD: 6.27, 95% CI: 1.47, 26.73, I2 =0%, P=0.01). Other outcomes were comparable between both groups. In conclusion, SCIT is slightly more effective than SLIT but is associated with a higher frequency of severe systemic reactions, guiding clinicians to tailor treatments to individual patient needs.</p>
Protocol for a systematic review: association between airborne pollen, intermittent allergic rhinitis and blood pressure
<p>Previous epidemiological studies have found an increased risk of cardiovascular morbidity and mortality following days with heightened pollen exposure and suggested that intermittent allergic rhinitis might be associated with blood pressure. Pollen sensitization and subsequent pollen exposure cause local inflammation and cytokine release in individuals with intermittent allergic rhinitis (pollen allergy). Inflammatory mediators can travel throughout the body, hence providing the physiologic basis by which pollen allergy may lead to systemic inflammation, which is known to be a risk factor for cardiovascular events. However, the findings regarding the potential association between intermittent allergic rhinitis, pollen exposure, and cardiovascular health are not fully conclusive. To date, no systematic review has been published on this topic.</p> <p>This systematic review seeks to answer: Are exposure to airborne pollen and intermittent allergic rhinitis associated with blood pressure? Secondary questions include: (1) Are there personal characteristics (sex, age) which modify a potential association between intermittent allergic rhinitis or pollen exposure with blood pressure and/or hypertension? (2) What research gaps exist in our understanding of how intermittent allergic rhinitis, pollen exposure, and cardiovascular health are interrelated?</p> <p>Published herein are:</p> <ul> <li>Protocol for the systematic review, including the search strategy</li> <li>Supplement 1: PROSPERO registration</li> <li>Supplement 2: Data extraction table</li> <li>Supplement 3: Risk of bias assessment strategy</li> <li>Supplement 4: Risk of bias assessment tool</li> </ul>
Health Risks Forecast of Regional Air Pollution on Allergic Rhinitis: High-Resolution City-Scale Simulations in Changchun, China
<p>Here presented the forcasted results of Potential Morbidity Risk Index (PMRI) for the personal patients with allerigc rhinitis and the public health administrations, and these results are supplied to the published paper of "Health Risks Forecast of Regional Air Pollution on Allergic Rhinitis: High-Resolution City-Scale Simulations in Changchun, China".</p>
Inverse influence of HLA-DR7, DR12 and DR13 on the pathogenesis of Der p 1-induced allergic rhinitis
<p>Supplementary tables and figures from the yet to be published study entitled "Inverse influence of HLA-DR7, DR12 and DR13 on the pathogenesis of Der p 1-induced allergic rhinitis".</p>
Clinical Trial to Assess the Efficacy and Safety of Ciclesonide Hydrofluoroalkane (HFA) Nasal Aerosol for the Treatment of Seasonal Allergic Rhinitis
ClinicalTrials.gov study NCT00790023. IPD Sharing: Not stated. Countries: 1. Publications: 1.
To Study GSP 301 in Patients With Seasonal Allergic Rhinitis
ClinicalTrials.gov study NCT02318303. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Nasacort AQ Hypothalamic-Pituitary-Adrenal (HPA) Axis Study in Children With Allergic Rhinitis
ClinicalTrials.gov study NCT01154153. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Efficacy and Safety of 100IR, 300IR, 500IR Sublingual House Dust Mite Tablets in Allergic Rhinitis Environment Exposure Chamber Model
ClinicalTrials.gov study NCT01527188. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Long-Term Study of TAU-284 in Pediatric Patients With Perennial Allergic Rhinitis
ClinicalTrials.gov study NCT01900054. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Study to Evaluate the Safety and Tolerability of a Nasal Spray to Treat Perennial Allergic Rhinitis
ClinicalTrials.gov study NCT00720382. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Study to Assess Intranasal Repeat Dose Effect of Levocabastine in the Subjects With Allergic Rhinitis
ClinicalTrials.gov study NCT01949051. IPD Sharing: YES. Countries: 1. Publications: 1.
A Study to Compare the Efficacy and Safety of Fluticasone Furoate Nasal Sprays (FFNS) 55 Microgram (mcg) and 110 mcg in Chinese Pediatric Subjects With Allergic Rhinitis (AR)
ClinicalTrials.gov study NCT02424539. IPD Sharing: YES. Countries: 1. Publications: 1.
The Addition of Montelukast to Fluticasone in the Treatment of Perennial Allergic Rhinitis
ClinicalTrials.gov study NCT00119015. IPD Sharing: Not stated. Countries: 1. Publications: 21.
Long Term Safety and Efficacy of Fixed Dose Combination GSP 301 Nasal Spray (NS) in the Treatment of Perennial Allergic Rhinitis (PAR)
ClinicalTrials.gov study NCT02709538. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Efficacy and Safety of GSP 301 Nasal Spray in Children (Aged 6 to Under 12 Years) With Seasonal Allergic Rhinitis (SAR)
ClinicalTrials.gov study NCT03463031. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Screening Scottish Swimmers for Asthma and Rhinitis
ClinicalTrials.gov study NCT00831428. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Comparator Study of Fluticasone Propionate Nasal Spray Verses (vs) Cetirizine in the Treatment of Seasonal Allergic Rhinitis
ClinicalTrials.gov study NCT01916226. IPD Sharing: YES. Countries: 1. Publications: 1.
Efficacy and Safety of GSP 301 Nasal Spray in the Treatment of Seasonal Allergic Rhinitis (SAR)
ClinicalTrials.gov study NCT02870205. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Efficacy Study in Allergic Rhinitis Patients After Intranasal Administration of AZD8848
ClinicalTrials.gov study NCT01185080. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Fluticasone Furoate Nasal Spray for 2 Weeks in Chinese Adult and Adolescent Subjects With Allergic Rhinitis
ClinicalTrials.gov study NCT01231464. IPD Sharing: Not stated. Countries: 1. Publications: 1.
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