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63 results for “riboflavin”
Whole genome sequence data of Mycobacterium tuberculosis and Mycolicibacterium smegmatis mutants of the riboflavin biosynthetic pathway- Part 1
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Whole genome sequence data of Mycobacterium tuberculosis and Mycolicibacterium smegmatis mutants of the riboflavin biosynthetic pathway- Part 2
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Supplemental Videos for: Association of SLC52A3a [p. L267P] and [p. T278M] with riboflavin transportation in esophageal cancer cells
<p>Supplemental data</p> <p>Supplemental Video S1 showing motility of GFP-SLC52A3a-WT containing vesicles in KYSE150 R<sup>+</sup> cells; </p> <p>Supplemental Video S2 showing motility of GFP-SLC52A3a-WT containing vesicles in KYSE150 R<sup>-</sup> cells; </p> <p>Supplemental Video S3 showing motility of GFP-SLC52A3a-L267P containing vesicles in KYSE150 R<sup>+</sup> cells;</p> <p>Supplemental Video S4 showing motility of GFP-SLC52A3a-L267P containing vesicles in KYSE150 R<sup>-</sup> cells;</p> <p>Supplemental Video S5 showing motility of GFP-SLC52A3a-T278M containing vesicles in KYSE150 R<sup>+</sup> cells;</p> <p>Supplemental Video S6 showing motility of GFP-SLC52A3a-T278M containing vesicles in KYSE150 R<sup>-</sup> cells;</p> <p>Supplemental Video S7 showing motility of GFP-SLC52A3a-L267/T278M containing vesicles in KYSE150 R<sup>+</sup> cells;</p> <p>Supplemental Video S8 showing motility of GFP-SLC52A3a-L267/T278M containing vesicles in KYSE150 R<sup>-</sup> cells.</p>
Data from: Pathogen reduction of monkeypox virus in plasma and whole blood using riboflavin and UV light
<p>Background</p> <p>Monkeypox virus has recently emerged from endemic foci in Africa and, to date, several hundred human infections have been reported from at least 16 non-African countries. The detection of virus in skin lesions, blood, semen, and saliva of infected patients with monkeypox infections raises the potential for disease transmission via routes that have not been previously documented, including by blood and plasma transfusions. Methods for protecting the blood supply against the threats of newly emerging disease agents exist and include Pathogen Reduction Technologies (PRT) which utilize photochemical treatment processes to inactivate pathogens in blood while preserving the integrity of plasma and cellular components. Such methods have been employed broadly for over 15 years, but effectiveness of these methods under routine use conditions against monkeypox virus has not been reported.</p> <p>Results</p> <p>The levels of spiked virus present in whole blood and plasma samples exceeded 103 infectious particles per dose, corresponding to greater than 105 DNA copies per mL. Treatment of whole blood and plasma units under standard operating procedures for the Mirasol PRT System resulted in complete inactivation of infectivity to the limits of detection. This is equivalent to a reduction of ≥ 2.86 +/- 0.73 log10 pfu/mL of infectivity in whole blood and ≥ 3.47 +/-0.19 log10 pfu/mL of infectivity in plasma under standard operating conditions for those products. </p> <p>Conclusion</p> <p>Based on this data and corresponding studies on infectivity in patients with monkeypox infections, use of Mirasol PRT would be expected to significantly reduce the risk of transfusion transmission of monkeypox.</p>
The Effect of Riboflavin in Crohn's Disease
ClinicalTrials.gov study NCT02538354. IPD Sharing: Not stated. Countries: 1. Publications: 9.
Data from: Pathogen reduction of monkeypox virus in plasma and whole blood using riboflavin and UV light
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Targeted metabolomics data for riboflavin, FMN and FAD in <em>Mycobacteria tuberculosis</em> and <em>Mycolicibacterium smegmatis</em>
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Targeted metabolomics data for dimethyl-ribityl lumazine (DMRL) and riboflavin in Mycobacterium tuberculosis and Mycolicibacterium smegmatis mutants of the riboflavin biosynthetic pathway
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A predictive model of UV-A-riboflavin crosslinking treatment on porcine corneas
<p>The crosslinking technique (CXL) is an effective low-risk therapeutic treatment of keratoconus and other ectatic disorders of the human cornea. The effect of corneal CXL is to increase the stiffness of the stroma to prevent the progression of the cornea distortion. Several clinical and experimental studies have shown that the stiffening effects predominantly localise on the anterior portion of the stroma and that the in-depth stiffening distribution is highly dependent on the duration of treatment. Yet, how the stiffening effects distribute through the cornea thickness as a function of the treatment duration is an open question. Here we propose an analytical model of the stiffening profile due to CXL-treatment as a function of the irradiation time. We consider linear and nonlinear variations of the crosslinking effects across the thickness and implement them into a finite element model of the porcine cornea. We present a time-dependent in-depth stiffening profile that allows us to predict the post-operative cornea response to physiological intraocular pressure for different irradiation times. We anticipate that this predictive model will support the development of patient specific 3D models that will allow clinicians to design customised CXL treatment, thus enhancing treatment outcomes. </p>
Efficacy of Riboflavin-Enhanced Hyaluronic Acid Eye Drops in Treating Dry Eye Disease
ClinicalTrials.gov study NCT06122428. IPD Sharing: YES. Countries: 1. Publications: 1.
Evaluation of Topical Riboflavin Exposed to UVA Radiation and Implantation of Corneal Ring
ClinicalTrials.gov study NCT00832897. IPD Sharing: Not stated. Countries: 1. Publications: 4.
Corneal Collagen Crosslinking With Riboflavin for Keratoconus Treatment: A Brazilian Study
ClinicalTrials.gov study NCT00642044. IPD Sharing: Not stated. Countries: 1. Publications: 7.
Topo-pachimetric Accelerated Epi-On Cross-linking Compared to Dresden Protocol Using Riboflavin With Vitamin E TPGS
ClinicalTrials.gov study NCT05019768. IPD Sharing: NO. Countries: 1. Publications: 2.
Corneal Collagen Cross-linking With Hypotonic Riboflavin in Corneas Thinner Than 400 Microns
ClinicalTrials.gov study NCT00890266. IPD Sharing: Not stated. Countries: 1. Publications: 1.
The Impact of Riboflavin on Sports-related Concussion
ClinicalTrials.gov study NCT02772237. IPD Sharing: NO. Countries: 1. Publications: 11.
Riboflavin-UVA Induced Collagen Crosslinking Treatment for Corneal Ectasia
ClinicalTrials.gov study NCT01123057. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Safety and Feasibility of ActivSight(tm) in the Identification of The Ureter Via Riboflavin Fluorescence
ClinicalTrials.gov study NCT06535555. IPD Sharing: NO. Countries: 1. Publications: 7.
Riboflavin at 4ºC for the Management of Pain After Crosslinking for Keratoconus Patients
ClinicalTrials.gov study NCT03760770. IPD Sharing: NO. Countries: 1. Publications: 17.
The Impact of Riboflavin on the Severity and Duration of Sports Related Concussion
ClinicalTrials.gov study NCT02235337. IPD Sharing: Not stated. Countries: 1. Publications: 11.
Riboflavin Mediated Corneal Crosslinking for Stabilizing Progression of Keratoconus
ClinicalTrials.gov study NCT00626717. IPD Sharing: Not stated. Countries: 1. Publications: 1.
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Allen Brain Atlas
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International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.