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24 results for “saturated fatty acids”
Data from: Increased dietary intake of saturated fatty acid heptadecanoic acid (C17:0) associated with decreasing ferritin and alleviated metabolic syndrome in dolphins
Similar to humans, bottlenose dolphins (Tursiops truncatus) can develop metabolic syndrome and associated high ferritin. While fish and fish-based fatty acids may protect against metabolic syndrome in humans, findings have been inconsistent. To assess potential protective factors against metabolic syndrome related to fish diets, fatty acids were compared between two dolphin populations with higher (n = 30, Group A) and lower (n = 19, Group B) mean insulin (11 ± 12 and 2 ± 5 μIU/ml, respectively; P < 0.0001) and their dietary fish. In addition to higher insulin, triglycerides, and ferritin, Group A had lower percent serum heptadecanoic acid (C17:0) compared to Group B (0.3 ± 0.1 and 1.3 ± 0.4%, respectively; P < 0.0001). Using multivariate stepwise regression, higher percent serum C17:0, a saturated fat found in dairy fat, rye, and some fish, was an independent predictor of lower insulin in dolphins. Capelin, a common dietary fish for Group A, had no detectable C17:0, while pinfish and mullet, common in Group B's diet, had C17:0 (41 and 67 mg/100g, respectively). When a modified diet adding 25% pinfish and/or mullet was fed to six Group A dolphins over 24 weeks (increasing the average daily dietary C17:0 intake from 400 to 1700 mg), C17:0 serum levels increased, high ferritin decreased, and blood-based metabolic syndrome indices normalized toward reference levels. These effects were not found in four reference dolphins. Further, higher total serum C17:0 was an independent and linear predictor of lower ferritin in dolphins in Group B dolphins. Among off the shelf dairy products tested, butter had the highest C17:0 (423mg/100g); nonfat dairy products had no detectable C17:0. We hypothesize that humans' movement away from diets with potentially beneficial saturated fatty acid C17:0, including whole fat dairy products, could be a contributor to widespread low C17:0 levels, higher ferritin, and metabolic syndrome.
The Acute Effects of Meals Rich in Saturated or Unsaturated Fatty Acids on Postprandial Lipaemia in Healthy Men
ClinicalTrials.gov study NCT05264233. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Saturated Fatty Acids and HDL Metabolism
ClinicalTrials.gov study NCT02835651. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Data from: Increased dietary intake of saturated fatty acid heptadecanoic acid (C17:0) associated with decreasing ferritin and alleviated metabolic syndrome in dolphins
Open the record for dataset details and reuse information.
Saturated Fatty Acids Intake and Mortality, Diabetes, Hypertension and Overweight
ClinicalTrials.gov study NCT03281512. IPD Sharing: Not stated. Countries: 0. Publications: 1.
Long-chain saturated fatty acids in breast milk are associated with the pathogenesis of atopic dermatitis via inducing inflammatory ILC3s
GEO Series GSE124182. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Lineage-restricted regulation of SCD and fatty acid saturation by MITF controls melanoma phenotypic plasticity
GEO Series GSE137390. Homo sapiens. 36 samples. Type: Expression profiling by high throughput sequencing.
Dietary saturated fatty acids promote lung myeloid cell inflammasome activation and IL-1β-mediated inflammation in mice and humans
GEO Series GSE297606. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Effect of inhibition of PI3-Kinase p110alpha on saturated fatty acid-induced gene expression alterations in murine 3T3-L1 adipocytes
GEO Series GSE129442. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Saturated fatty acids promotes β-cell toxicity by disabling intracellular lipid droplet formation through S-acylation of FIT2
GEO Series GSE133939. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.
Postprandial Lipid Metabolism in Patients With Hypertriglyceridemia and Normo-lipidemic Controls: Medium Chain Fatty Acids (MCT) in Comparison to Long-chain, Saturated Fatty Acids (SFA) and Mono-unsat
ClinicalTrials.gov study NCT03846908. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Impact of Vaccenic Acid Consumption on the Metabolism of Saturated Fatty Acids: Relationship With Cardiovascular Risk Factors
ClinicalTrials.gov study NCT00685581. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Is Omega-3 Fatty Acid Red Blood Cell (RBC) Saturation Product Dependent?
ClinicalTrials.gov study NCT01091714. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Ovarian cancer cell fate regulation by the dynamics between saturated and unsaturated fatty acids
GEO Series GSE192442. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
ZDHHC12 palmitoylates HDAC8 and promotes the development of hepatocellular carcinoma associated with a diet high in saturated fatty acids
GEO Series GSE290907. Homo sapiens. 30 samples. Type: Expression profiling by high throughput sequencing.
RNA-sequencing identifies dysregulation of the human pancreatic islet transcriptome by the saturated fatty acid palmitate
GEO Series GSE53949. Homo sapiens. 10 samples. Type: Expression profiling by high throughput sequencing; Third-party reanalysis.
Saturated fatty acids regulate retinoic acid signaling and suppress tumorigenesis by targeting fatty acid-binding protein 5
GEO Series GSE73186. Mus musculus. 18 samples. Type: Expression profiling by array.
MITF regulates SCD and fatty acid saturation to control melanoma phenotypic state.
GEO Series GSE137392. Homo sapiens. 60 samples. Type: Expression profiling by high throughput sequencing.
Dietary medium-chain saturated fatty acids induce gene expression of energy metabolism-related pathways in adipose tissue of abdominally obese subjects
GEO Series GSE87382. Homo sapiens. 24 samples. Type: Expression profiling by array.
Novel Lipogenic Enzyme ELOVL7 Involves in Prostate Cancer Growth through Saturated Fatty-acid and Steroid Metabolism
GEO Series GSE14852. Homo sapiens. 6 samples. Type: Expression profiling by array.
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Allen Brain Atlas
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Annotated Behaviour and Observability Dataset (ABODe)
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
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