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26 results for “seed toxicity”

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dryad32/100

Data from: The distribution of fruit and seed toxicity during development for eleven Neotropical trees and vines in Central Panama

Secondary compounds in fruit mediate interactions with natural enemies and seed dispersers, influencing plant survival and species distributions. The functions of secondary metabolites in plant defenses have been well-studied in green tissues, but not in reproductive structures of plants. In this study, the distribution of toxicity within plants was quantified and its influence on seed survival was determined in Central Panama. To investigate patterns of allocation to chemical defenses and shifts in allocation with fruit development, I quantified variation in toxicity between immature and mature fruit and between the seed and pericarp for eleven species. Toxicity of seed and pericarp was compared to leaf toxicity for five species. Toxicity was measured as reduced hyphal growth of two fungal pathogens, Phoma sp. and Fusarium sp., and reduced survivorship of brine shrimp, Artemia franciscana, across a range of concentrations of crude extract. I used these measures of potential toxicity against generalist natural enemies to examine the effect of fruit toxicity on reductions of fruit development and seed survival by vertebrates, invertebrates, and pathogens measured for seven species in a natural enemy removal experiment. The seed or pericarp of all vertebrate- and wind-dispersed species reduced Artemia survivorship and hyphal growth of Fusarium during the immature and mature stages. Only mature fruit of two vertebrate-dispersed species reduced hyphal growth of Phoma. Predispersal seed survival increased with toxicity of immature fruit to Artemia during germination and decreased with toxicity to fungi during fruit development. This study suggests that fruit toxicity against generalist natural enemies may be common in Central Panama. These results support the hypothesis that secondary metabolites in fruit have adaptive value and are important in the evolution of fruit-frugivore interactions.

opencc-zeroDec 2012View details →
ClinicalTrials.gov32/100

Feasibility and Toxicity of Degarelix for Prostate Downsizing Prior to Permanent Seed Prostate Brachytherapy

ClinicalTrials.gov study NCT01446991. IPD Sharing: Not stated. Countries: 1. Publications: 1.

restrictedIPD-UNDECIDEDFeb 2026View details →
dryad32/100

Data from: The distribution of fruit and seed toxicity during development for eleven Neotropical trees and vines in Central Panama

Open the record for dataset details and reuse information.

publicJul 2013View details →
ClinicalTrials.gov28/100

Broccoli Sprout/Broccoli Seed Extract Supplement in Decreasing Toxicity in Heavy Smokers

ClinicalTrials.gov study NCT03402230. IPD Sharing: Not stated. Countries: 1. Publications: 0.

restrictedIPD-UNDECIDEDFeb 2026View details →
geo24/100

6mer seed toxicity in tumour suppressive microRNAs

GEO Series GSE111379. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenSep 2018View details →
geo24/100

Identification of the toxic 6mer seed consensus for human cancer cells

GEO Series GSE196839. Homo sapiens. 16 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenFeb 2022View details →
geo24/100

6mer seed toxicity in viral microRNAs

GEO Series GSE135453. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenNov 2019View details →
geo24/100

Contribution of 6mer seed toxicity to HIV-1 induced cytotoxicity [DISE-19]

GEO Series GSE218187. Homo sapiens. 8 samples. Type: Non-coding RNA profiling by high throughput sequencing; Other.

openGEO-OpenJun 2023View details →
geo24/100

Contribution of 6mer seed toxicity to HIV-1 induced cytotoxicity (DISE-45)

GEO Series GSE218192. Homo sapiens. 12 samples. Type: Non-coding RNA profiling by high throughput sequencing; Other.

openGEO-OpenJun 2023View details →
geo24/100

Contribution of 6mer seed toxicity to HIV-1 induced cytotoxicity [DISE-42]

GEO Series GSE218191. Homo sapiens. 18 samples. Type: Non-coding RNA profiling by high throughput sequencing; Other.

openGEO-OpenJun 2023View details →
geo24/100

Contribution of 6mer seed toxicity to HIV-1 induced cytotoxicity [DISE-56]

GEO Series GSE218193. Homo sapiens. 18 samples. Type: Non-coding RNA profiling by high throughput sequencing; Other.

openGEO-OpenJun 2023View details →
geo24/100

SPOROS: A pipeline to analyze DISE/6mer Seed Toxicity

GEO Series GSE182222. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenAug 2021View details →
geo24/100

Contribution of 6mer seed toxicity to HIV-1 induced cytotoxicity [DISE-36]

GEO Series GSE218189. Homo sapiens. 8 samples. Type: Non-coding RNA profiling by high throughput sequencing; Other.

openGEO-OpenJun 2023View details →
geo24/100

Identification of the most toxic 6mer seed consensus and some of its targets in human cells

GEO Series GSE164289. Homo sapiens. 10 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenDec 2021View details →
geo20/100

Contribution of 6mer seed toxicity to HIV-1 induced cytotoxicity

GEO Series GSE218195. Homo sapiens. 68 samples. Type: Non-coding RNA profiling by high throughput sequencing; Other; Expression profiling by high throughput sequencing.

openGEO-OpenJun 2023View details →
geo20/100

Contribution of 6mer seed toxicity to HIV-1 induced cytotoxicity (DISE-69)

GEO Series GSE218194. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJun 2023View details →
geo20/100

Sperm miRNA expression differences between bulls consuming toxic and non-toxic tall fescue seed

GEO Series GSE61745. synthetic construct; Bos taurus. 6 samples. Type: Non-coding RNA profiling by array.

openGEO-OpenDec 2014View details →
geo20/100

Sperm miRNA from bulls consuming toxic and non-toxic tall fescue seed

GEO Series GSE61747. Bos taurus; synthetic construct. 7 samples. Type: Non-coding RNA profiling by array; Non-coding RNA profiling by high throughput sequencing.

openGEO-OpenDec 2014View details →
geo12/100

6mer Seed toxicity and platinum resistance in ovarian cancer

GEO Series GSE165148. Homo sapiens. 100 samples. Type: Non-coding RNA profiling by high throughput sequencing.

openGEO-OpenFeb 2021View details →
geo12/100

6mer Seed toxicity and platinum resistance in ovarian cancer [DISE-41]

GEO Series GSE165617. Homo sapiens. 12 samples. Type: Non-coding RNA profiling by high throughput sequencing.

openGEO-OpenFeb 2021View details →

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