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87 results for “stress hormones”
Stress-associated brain activation across the hormonal contraceptive cycle
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Elevated temperature effects on animal personality: hormonal stress response underlying behavioural differences in the American bullfrog
<p>Dataset for research paper submitted to Animal Behaviour</p> <p>Behavioural_data.csv: raw data for how individual bullfrogs performed in six different trials on an 8-arm maze before and after they were submitted to thermal stress. Behaviours analyzed: movements against the wall of the maze, posture changes, total ambulatory distance (m), and time on the centre of the arena (s).</p> <p>Hormone_data.csv: raw hormone (corticosterone and testosterone) data collected from individual bullfrogs in four different time points: baseline, 12 hours after stress, 24 days after stress, and 47 days after stress.</p> <p>Mass_data.csv: raw mass data collected from individual bullfrogs at the beginning and end of the experiment. SVL = snout-vent length. Body index is calculated as the residuals of a linear regression between mass as dependent variable and SVL as independent variable.</p>
Data of "Poor repeatability of cortisol responses to adrenocorticotropic hormone (ACTH) in beef heifers: is the ACTH challenge a suitable measure for stress research in cattle?"
<p>Data for article "Poor repeatability of cortisol responses to adrenocorticotropic hormone (ACTH) in beef heifers: is the ACTH challenge a suitable measure for stress research in cattle?" Dataset of 64 crossbred beef heifers which were subjected to three ACTH challenges. Both experimental independent variables (animal id, horn status, replicate, time of day of the ACTH challenge, ACTH challenge number) and post-ACTH salivary cortisol concentrations (at the seven sampling timepoints and area under the curve values) are presented.</p>
Data for: Compensating for a stressful pregnancy? Glucocorticoid treatment during gravidity reduces metabolic rate in female fence lizards post-parturition (In press: Hormones and Behavior)
<p>This dataset accompanies the paper "Compensating for a stressful pregnancy? Glucocorticoid treatment during gravidity reduces metabolic rate in female fence lizards post-parturition" (In press: Hormones and Behavior). A READ_ME/metadata explanation is available in Sheet 1. Address any queries to Dr. K. MacLeod, kirstyjmacleod@gmail.com.</p> <p>Abstract: Reproduction is a critical part of an animal’s life history, but one which incurs significant costs to survival and future reproductive potential. These physiological consequences are likely to be influenced by context – for example, if an individual is subject to environmental stressors, physiological and behavioral changes associated with reproduction may be altered. Glucocorticoids, hormones produced as part of the physiological response to stressors, may alter how reproduction affects female physiology and behavior, and therefore the outcomes of reproductive trade-offs. Glucocorticoids prioritize immediate survival over reproduction, for example through changes in immune function, metabolic rate, and foraging, which may reduce energy expenditure or increase energy gain. However, we previously found that female eastern fence lizards (<em>Sceloporus undulatus</em>) experiencing elevated glucocorticoid levels during gestation were nevertheless able to maintain reproductive output and body condition. Here we investigate compensatory mechanisms by which eastern fence lizard females may maintain reproduction under experimental increases in a glucocorticoid, corticosterone (CORT). We found that, although CORT-treated females had similar immune function and behavior, they had reduced metabolic rates 3-5 days post-parturition compared to control females. Given that CORT-treated females spent a similar time basking and had equal food intake compared to control females, we suggest that the reduced metabolic rate is a mechanism by which CORT-treated females maintain their energy balance and reduce the energetic costs of gestation during periods of stress. This study suggests that physiological responses to reproduction may be context-dependent and could act to minimize costs of reproduction in situations where CORT is elevated (such as during periods of environmental stress). </p>
Prior parental experience attenuates hormonal stress responses and alters hippocampal glucocorticoid receptors in biparental rock doves
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Data from: Stress hormone receptors change as range expansion progresses in house sparrows
As ranges expand, individuals encounter different environments at the periphery than at the centre of the range. Previously, we have shown that glucocorticoids (GCs) vary with range expansion: individuals at the range edge release more GCs in response to restraint. Here, we measured hippocampal mRNA expression of GC receptors (mineralocorticoid, MR and glucocorticoid, GR) in eight house sparrow (Passer domesticus) populations varying in age. We found that individuals closest to the range edge had the lowest expression of MR relative to GR; in all likelihood, this relationship was driven by a marginal reduction of MR mRNA at the range edge. Reduced MR (relative to GR) might allow enhanced GC binding to GR, the lower affinity receptor that would enhance a rapid physiological and behavioural response to stressors. The insights gained from this study are not only enlightening to introduced species, but may also predict how certain species will react as their ranges shift owing to anthropogenic changes.
Data from: Stress hormones predict a host superspreader phenotype in the West Nile virus system
Glucocorticoid stress hormones, such as corticosterone (CORT), have profound effects on the behaviour and physiology of organisms, and thus have the potential to alter host competence and the contributions of individuals to population- and community-level pathogen dynamics. For example, CORT could alter the rate of contacts among hosts, pathogens and vectors through its widespread effects on host metabolism and activity levels. CORT could also affect the intensity and duration of pathogen shedding and risk of host mortality during infection. We experimentally manipulated songbird CORT, asking how CORT affected behavioural and physiological responses to a standardized West Nile virus (WNV) challenge. Although all birds became infected after exposure to the virus, only birds with elevated CORT had viral loads at or above the infectious threshold. Moreover, though the rate of mortality was faster in birds with elevated CORT compared with controls, most hosts with elevated CORT survived past the day of peak infectiousness. CORT concentrations just prior to inoculation with WNV and anti-inflammatory cytokine concentrations following viral exposure were predictive of individual duration of infectiousness and the ability to maintain physical performance during infection (i.e. tolerance), revealing putative biomarkers of competence. Collectively, our results suggest that glucocorticoid stress hormones could directly and indirectly mediate the spread of pathogens.
Data from: Cascading effects of thermally-induced anemone bleaching on associated anemonefish hormonal stress response and reproduction
Organisms can behaviorally, physiologically, and morphologically adjust to environmental variation via integrative hormonal mechanisms, ultimately allowing animals to cope with environmental change. The stress response to environmental and social changes commonly promotes survival at the expense of reproduction. However, despite climate change impacts on population declines and diversity loss, few studies have attributed hormonal stress responses, or their regulatory effects, to climate change in the wild. Here, we report hormonal and fitness responses of individual wild fish to a recent large-scale sea warming event that caused widespread bleaching on coral reefs. This 14-month monitoring study shows a strong correlation between anemone bleaching (zooxanthellae loss), anemonefish stress response, and reproductive hormones that decreased fecundity by 73%. These findings suggest that hormone stress responses play a crucial role in changes to population demography following climate change and plasticity in hormonal responsiveness may be a key mechanism enabling individual acclimation to climate change.
Data from: Lactation and resource limitation affect stress responses, thyroid hormones, immune function and antioxidant capacity of sea otters (Enhydra lutris)
1. Lactation is the most energetically demanding stage of reproduction in female mammals. Increased energetic allocation toward current reproduction may result in fitness costs, though the mechanisms underlying these trade-offs are not well understood. Trade-offs during lactation may include reduced energetic allocation to cellular maintenance, immune response and survival, and may be influenced by resource limitation. 2. As the smallest marine mammal, sea otters (Enhydra lutris) have the highest mass-specific metabolic rate necessitating substantial energetic requirements for survival. To provide the increased energy needed for lactation, female sea otters significantly increase foraging effort, especially during late-lactation. Caloric insufficiency during lactation is reflected in the high numbers of maternal deaths due to End-Lactation Syndrome in the California subpopulation. 3. We investigated the effects of lactation and resource limitation on maternal stress responses, metabolic regulation, immune function and antioxidant capacity in two subspecies of wild sea otters (northern: E. l. nereis and southern: E. l. kenyoni) within the California, Washington and Alaska subpopulations. 4. Lactation and resource limitation were associated with reduced glucocorticoid responses to acute capture stress. Corticosterone release was lower in lactating otters. Cortisol release was lower under resource limitation and suppression during lactation was only evident under resource limitation. Lactation and resource limitation were associated with alterations in thyroid hormones. Immune responses and total antioxidant capacity were not reduced by lactation or resource limitation. Southern sea otters exhibited higher concentrations of antioxidants, immunoglobulins and thyroid hormones than northern sea otters. 5. These data provide evidence for allocation trade-offs during reproduction and in response to nutrient limitation but suggest self-maintenance of immune function and antioxidant defenses despite energetic constraints. Income-breeding strategists may be especially vulnerable to the consequences of stress and modulation of thyroid function when food resources are insufficient to support successful reproduction and may come at a cost to survival, and thereby influence population trends.
Data from: Host stress hormones alter vector feeding preferences, success, and productivity
Stress hormones might represent a key link between individual-level infection outcome, population-level parasite transmission, and zoonotic disease risk. Although the effects of stress on immunity are well known, stress hormones could also affect host–vector interactions via modification of host behaviours or vector-feeding patterns and subsequent reproductive success. Here, we experimentally manipulated songbird stress hormones and examined subsequent feeding preferences, feeding success, and productivity of mosquito vectors in addition to defensive behaviours of hosts. Despite being more defensive, birds with elevated stress hormone concentrations were approximately twice as likely to be fed on by mosquitoes compared to control birds. Moreover, stress hormones altered the relationship between the timing of laying and clutch size in blood-fed mosquitoes. Our results suggest that host stress could affect the transmission dynamics of vector-borne parasites via multiple pathways.
High-throughput phenotyping of salt-stress responses of the selected Arabidopsis hormone mutants
<p>This data was collected using Hight Throughput Phenotyping machine (psi.cz) purchased by KAUST in January 2018. The plants were germinated and grown under 12/12 light/dark light regime, 22C, 60% humidity for two weeks. After two weeks, half of the plants were exposed to approximately 100 mM NaCl (protocol described in Awlia et al., 2016, Frontiers in Plant Sci, <a href="https://doi.org/10.3389/fpls.2016.01414">https://doi.org/10.3389/fpls.2016.01414</a>). The rosettes of the plants were subsequently phenotyped using the Thermal Camera, RGB, and Chlorophyll Fluorescence camera (in this order). Chlorophyll fluorescence was measured after 15 minutes of dark adaptation using the "LightCurve2" protocol. </p> <p>The description of the traits is available in the notebook available at <a href="https://github.com/mmjulkowska/PSI_notebook">https://github.com/mmjulkowska/PSI_notebook</a> </p>
Stress Hormones and IUDs
ClinicalTrials.gov study NCT03499379. IPD Sharing: NO. Countries: 1. Publications: 1.
Cytokine and Stress Hormone Responses to Exercise-induced Hypoxemia Among Endurance-trained
ClinicalTrials.gov study NCT04305873. IPD Sharing: Not stated. Countries: 1. Publications: 22.
Counter-Regulatory Hormonal and Stress Systems in Patients With COVID-19
ClinicalTrials.gov study NCT05736900. IPD Sharing: Not stated. Countries: 1. Publications: 4.
Effects of Stress Hormones on Emotion and Cognition
ClinicalTrials.gov study NCT00032838. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Endotoxin & Cytokines. Do Protein Loss and Metabolic Effects Depend on Central Nervous System (CNS) Activation of Stress Hormones or on Local Mechanisms in Muscle and Fat?
ClinicalTrials.gov study NCT01452958. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Physiological, Hormonal, and DNA-based Mechanisms of Psychosocial Stress and Therapeutic Effect
ClinicalTrials.gov study NCT07152652. IPD Sharing: NO. Countries: 1. Publications: 4.
Acupuncture and Gonadotropin-releasing Hormone Pulse Generator and Stress Axis in Polycystic Ovary Syndrome
ClinicalTrials.gov study NCT00921492. IPD Sharing: Not stated. Countries: 1. Publications: 1.
COMPARISON OF OXIDANT-ANTIOXIDANT LEVELS WITH STRESS HORMONES IN SPINAL ANESTHESIA AND GENERAL ANESTHESIA IN LAPAROSCOPIC TUBE LIGATION
ClinicalTrials.gov study NCT06710522. IPD Sharing: YES. Countries: 1. Publications: 2.
Remifentanil and Stress Hormones Response
ClinicalTrials.gov study NCT03378674. IPD Sharing: Not stated. Countries: 1. Publications: 4.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.