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46 results for “tissue shape”

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zenodo44/100

Data: An Injectable Meta-biomaterial: From Design and Simulation to In-vivo Shaping and Tissue induction

<p><strong>Dataset supporting the manuscript "</strong>An Injectable Meta-biomaterial: From Design and Simulation to In-vivo Shaping and Tissue induction<strong>" by the authors of this dataset.</strong></p> <p><strong>Where to start</strong></p> <p>This Zenodo repository contains both raw data and runnable code for the manuscript "An Injectable Meta-biomaterial: From Design and Simulation to In-vivo Shaping and Tissue induction". The runnable code is best executed directly at CodeOcean (https://doi.org/10.24433/CO.6934377.v1). Alternatively, CodeOcean capsules are Docker images and can be run locally after download and unzipping. The full CodeOcean capsule is stored here as "CodeOceanCapsule_Injectable_meta_biomaterial.zip", it contains all the information and data to full reproduce the evaluation underpinning the manuscript "&nbsp;An Injectable Meta-biomaterial: From Design and Simulation to In-vivo Shaping and Tissue induction".</p> <p>Quantitative raw data, in the form of text files, Excel files and R-data files useful for the data evaluation are included in "CodeOceanCapsule_Injectable_meta_biomaterial.zip". As especially the numerical simulation files are rather voluminous (100GB), we also provide a copy of the capsule without this large part, which however otherwise remains runnable for most evaluations ("CodeOceanCapsule_Injectable_meta_biomaterial_no_raw_simulation.zip"), and, for lightweight documentation of the code section only "CodeOceanCapsule_Injectable_meta_biomaterial_code_only.zip". The results of a capsule run are also provided, as "CodeOceanCapsule_Injectable_meta_biomaterial_results_run_4899036.zip".</p> <p>Besides archival of the CodeOcean evaluation capsule, this repository contains additional imaging data from which some of the quantitative data treated in the CodeOcean capsule was extracted, and additionally raw files for the illustrative figures in the manuscript. This data is contained in the files "Raw_images_For_Figure_1.zip", "Raw_images_For_Figure_3.zip", "Raw_images_For_Figure_4.zip";&nbsp;"Raw_images_For_Figure_5.zip",&nbsp;"Raw_images_For_SFigure_S6.zip",&nbsp;"Raw_images_For_SFigure_S8.zip", "Raw_images_For_SFigure_S9.zip", "Raw_images_For_SFigure_S19.zip".</p> <p><strong>External dependencies</strong></p> <p>To facilitate centralized software development and installation, custom R and Python libraries used by the CodeOcean capsule&nbsp;"CodeOceanCapsule_Injectable_meta_biomaterial.zip" are hosted on Github, with releases archived in separate Zenodo repositories. These libraries are included automatically during the build phase of the CodeOcean capsule.</p> <p>This concerns the Python discrete particle simulation particleShear (DOI: <a href="https://doi.org/10.5281/zenodo.4589212">10.5281/zenodo.4589212</a>), and the R packages textureAnalyzerGels (for analysis of mechanical compression curves, DOI: <a href="https://doi.org/10.5281/zenodo.4589276">10.5281/zenodo.4589276</a>), rheologyEvaluation (for analysis of oscillatory sweep rheology, DOI: <a href="https://doi.org/10.5281/zenodo.4594353">10.5281/zenodo.4594353</a>), particleShearEvaluation (evaluation of the output of the Python simulations, DOI: <a href="https://doi.org/10.5281/zenodo.4594649">10.5281/zenodo.4594649</a>), plot.counts (convenience functions for scientific plotting, DOI: <a href="https://doi.org/10.5281/zenodo.4589498">10.5281/zenodo.4589498</a>) and reproducibleCalculationTools (numerical comparision of subsequent evaluations to validate reproducibility, DOI: <a href="https://doi.org/10.5281/zenodo.4594515">10.5281/zenodo.4594515</a>).</p> <p>For automated evaluation of ImageJ macros from Excel files, we also developed an Excel macro runner plugin in ImageJ, termed PoreSizeExcel (DOI: <a href="https://doi.org/10.5281/zenodo.4589546">10.5281/zenodo.4589546</a>). While the R and Python libraries listed above are actively loaded and used by the CodeOcean capsule, we used the PoreSizeExcel ImageJ plugin manually to streamline our quantitative image treatment, but not in a fully automated fashin.</p> <p>The Zenodo archives cited above reproducibly provide the state of the libraries as used for evaluation of this dataset, we continue to develop the libraries and continuously make them available at Github ( at&nbsp;<a href="https://github.com/tbgitoo">https://github.com/tbgitoo</a> ).</p> <p><strong>Version history</strong></p> <p>This is the third version of this Zenodo repository.</p> <p>We undertook major efforts from version v1.0 to the present version v2.0 to increase reprodubility of evaluation (via the use of the CodeOcean platform) and via separation of generic libraries (listed above, and installable on their own independently of this particular project) from specific project-associated data and evaluation (here). For this reason, while the data is maintained and in part completed due to new experiments having been carried out in the mean time, the structure of the repository has undergone major changes from v1.0 to the present version v2.0.</p> <p>With this version v3.0 we added raw data on cell transplantation, and completed the CodeOcean capsule, including adaptation to peer review changes to the manuscript.</p>

opencc-by-4.0Apr 2019View details →
zenodo40/100

Raw data: Patterned apoptosis has an instructive role for local growth and tissue shape regulation in a fast-growing epithelium

<p>What regulates organ size and shape remains one fundamental mystery of modern biology. Research in this area has primarily focused on deciphering the regulation in time and space of growth and cell division, while the contribution of cell death has been overall neglected. This includes studies of the <i>Drosophila</i> wing, one of the best characterised systems for the study of growth and patterning, undergoing massive growth during larval stage and important morphogenetic remodeling during pupal stage. So far, it has been assumed that cell death was relatively neglectable in this tissue both during larval and pupal stage and as a result the pattern of growth was usually attributed to the distribution of cell division. Here, using systematic mapping and registration combined with quantitative assessment of clone size and disappearance as well as live imaging, we outline a persistent pattern of cell death and clone elimination emerging in the larval wing disc and persisting during pupal wing morphogenesis. Local variation of cell death is associated with local variation of clone size, pointing to an impact of cell death on local growth which is not fully compensated by proliferation. Using morphometric analyses of adult wing shape and genetic perturbations, we provide evidence that patterned death affects locally and globally adult wing shape and size. This study describes a roadmap for precise assessment of the contribution of cell death to tissue shape, and outlines an important instructive role of cell death in modulating quantitatively local growth and morphogenesis of a fast-growing tissue.</p><p>This repository contains the raw data (local projection images, ROI and quantificatiosn) of the Current Biology article "<strong>Patterned apoptosis has an instructive role for local growth and tissue shape regulation in a fast-growing epithelium".</strong></p>

opencc-by-4.0Dec 2023View details →
zenodo40/100

Text-fig. 8. Lanfrancia subglobosa E.REID et M.CHANDLER. a–c, e–g: Holotype V. 23014. a: reflected light. b, c: Surface renderings from micro-CT data. a, b: Lateral views with dorsal surface of locule facing forward and locule casts protruding in upper part. c: Apical view. d: Fruit showing two locule casts the dorsal surfaces of which face to the left and the right, V. 30417(1). e–g: Successive digital transverse sections showing four u to v to c-shaped locules from micro-CT data. h: Physical transverse section of specimen in (d). i–k: Physical transverse section, V. 30419 from Herne Bay, blue lines in K indicating limits of fibre layer lining the locule. l: Detail from (h), showing sclerenchyma composing the septa and central axis. m: Transverse section, enlargement from (i), showing anatomy of tissues adjacent to the dorsal infold. Blue lines indicate limits of the fibre layer lining the locule. n: Part of (m) recut, tangential section transecting the dorsal infold (central), both limbs of the locule cast, and peripheral parts of the pericarp on either side. o: Detail from (n), showing anatomy of the infold. Scale bars 5 mm in (a–h) (a–g share the same bar), 3 mm in (i), 1 mm in (j–m), 0.5 mm in (n), 0.2 mm in (o). in Mastixioid Fruits (Cornales) From The Early Eocene London Clay Flora: Morphology, Anatomy And Nomenclatural Revision

Text-fig. 8. Lanfrancia subglobosa E.REID et M.CHANDLER. a–c, e–g: Holotype V. 23014. a: reflected light. b, c: Surface renderings from micro-CT data. a, b: Lateral views with dorsal surface of locule facing forward and locule casts protruding in upper part. c: Apical view. d: Fruit showing two locule casts the dorsal surfaces of which face to the left and the right, V. 30417(1). e–g: Successive digital transverse sections showing four u to v to c-shaped locules from micro-CT data. h: Physical transverse section of specimen in (d). i–k: Physical transverse section, V. 30419 from Herne Bay, blue lines in K indicating limits of fibre layer lining the locule. l: Detail from (h), showing sclerenchyma composing the septa and central axis. m: Transverse section, enlargement from (i), showing anatomy of tissues adjacent to the dorsal infold. Blue lines indicate limits of the fibre layer lining the locule. n: Part of (m) recut, tangential section transecting the dorsal infold (central), both limbs of the locule cast, and peripheral parts of the pericarp on either side. o: Detail from (n), showing anatomy of the infold. Scale bars 5 mm in (a–h) (a–g share the same bar), 3 mm in (i), 1 mm in (j–m), 0.5 mm in (n), 0.2 mm in (o).

opencc-by-4.0Aug 2022View details →
zenodo40/100

Text-fig. 5. Mastixiopsis nyssoides KIRCHH. a, b, g–n: Organic preservation. a, b: Lignitic, unpermineralized, early Eocene Dorset Pipe clays at Arne, V. 40762. a: Ventral view (original illustration from pl. 18, fig. 1 of Chandler 1962). b: Transverse fracture, somewhat distorted by compression. c–f: Pyrite permineralization. c: Ventral view, V. 22963(1) from Sheppey, originally listed as Mastixia cantiensis. d: Lateral view, V. 22969 from Sheppey (identified as Mastixia grandis by Reid and Chandler 1933: pl. 25, fig. 8). e: Equatorial transverse physical section from (c). f: Equatorial transverse physical section from (d). g: Detail of pericarp from (e), showing endocarp formed of dense fibrous tissue, surrounded by mesocarp of anticlinally oriented larger cells. h: Detail of pericarp from (f). i–n: Type material from Eocene of Riestadt, Germany, MNB. i: Ventral view. j, k: Ventral and apical views of holotype. l: View of the transversely fractured surface from (j) showing horseshoe shaped locule. m: Equatorial transverse physical cut of the specimen in (i); note yellow resin cavity (arrow). n: Scanning electron microscopy of pericarp from (l) with locule lining at lower edge of image. Note dense endocarp tissue composed of small cells (fibres and sclereids), extending about 3/5 of distance to periphery, surrounded by mesocarp of larger, anticlinally oriented cells. Scale bars 1 cm in (a–f), (i–k), 1 mm in (g), 2 mm in (h), 3 mm in (l), m, 250 Μm in (n). Bar in (d) applies also to (c). Bar in (l) also applies to (m). Bar in (i) also applies to (j) and (k). in Mastixioid Fruits (Cornales) From The Early Eocene London Clay Flora: Morphology, Anatomy And Nomenclatural Revision

Text-fig. 5. Mastixiopsis nyssoides KIRCHH. a, b, g–n: Organic preservation. a, b: Lignitic, unpermineralized, early Eocene Dorset Pipe clays at Arne, V. 40762. a: Ventral view (original illustration from pl. 18, fig. 1 of Chandler 1962). b: Transverse fracture, somewhat distorted by compression. c–f: Pyrite permineralization. c: Ventral view, V. 22963(1) from Sheppey, originally listed as Mastixia cantiensis. d: Lateral view, V. 22969 from Sheppey (identified as Mastixia grandis by Reid and Chandler 1933: pl. 25, fig. 8). e: Equatorial transverse physical section from (c). f: Equatorial transverse physical section from (d). g: Detail of pericarp from (e), showing endocarp formed of dense fibrous tissue, surrounded by mesocarp of anticlinally oriented larger cells. h: Detail of pericarp from (f). i–n: Type material from Eocene of Riestadt, Germany, MNB. i: Ventral view. j, k: Ventral and apical views of holotype. l: View of the transversely fractured surface from (j) showing horseshoe shaped locule. m: Equatorial transverse physical cut of the specimen in (i); note yellow resin cavity (arrow). n: Scanning electron microscopy of pericarp from (l) with locule lining at lower edge of image. Note dense endocarp tissue composed of small cells (fibres and sclereids), extending about 3/5 of distance to periphery, surrounded by mesocarp of larger, anticlinally oriented cells. Scale bars 1 cm in (a–f), (i–k), 1 mm in (g), 2 mm in (h), 3 mm in (l), m, 250 Μm in (n). Bar in (d) applies also to (c). Bar in (l) also applies to (m). Bar in (i) also applies to (j) and (k).

opencc-by-4.0Aug 2022View details →
zenodo40/100

Physiological mechanisms and life history trade-offs shape in-tissue correlations of an essential micronutrient

<p>The Matlab code and dataset for the manuscript "Physiological mechanisms and life history trade-offs shape in-tissue correlations of an essential micronutrient". The dataset is packed in the ZIP archive 'Dataset_EjsmondTodisco_etal.zip' with variable description in the Matlab code file EjsmondTodisco_etal.m. To run the program, place the files EjsmondTodisco_etal.m and Fun_PlotResults.m in a catalog. The results are stored in two catalogs: 'ThReabsorptionAndSecretion' - modeling the rate of thiamine loss with processes of active reabsorption and secretion; and 'ThReabsorptionOnly' - modeling the rate of thiamine loss with the process of active reabsorption only. The ThReabsorptionAndSecretion catalog contains data for three life history types: iteroparity (baseline model), semelparity, and determinate growth (constant mass of somatic tissues in adults). For details see the manuscript by Ejsmond, Todisco et al.</p>

opencc-by-4.0Sep 2024View details →
zenodo40/100

Text-fig. 5. Reyispermum parvum gen. et sp. nov. seeds from the Early Cretaceous Vale de Água locality, Portugal; Synchrotron radiation X-ray tomographic microscopy (SRXTM, volume renderings). a) Holotype (S174178; Vale de Agua sample 141) in lateral view showing shape and cell pattern; remains of mounting media (¤). b) Cut volume rendering of seed (cut at yz0553) showing the slightly raised tissue immediately adjacent to the lower edge of the hilum (arrow head) and palisade-shaped cells of exotesta. c) Apical view of seed showing hilar depression (hi), position of micropylar slit (mi) and the slightly raised raphal ridge (ra). d) Seed in lateral view showing raised tissue immediately adjacent to the lower edge of the hilum (arrow head) (S174495, Vale de Água sample 300). e) Cut volume rendering (cut at yz0500) of the seed in (5d) showing the raised tissue (arrow head) immediately adjacent to the lower edge of the hilum and sclerenchyma cells of exotesta. f) Detail of seed in (5d) showing micropylar slit (mi), hilum (hi) and raised tissue (arrow head) immediately adjacent to the lower edge of the hilum. g, h) Seed in lateral view (g) and view towards raphe (h) showing seed shape, the raised tissue below hilum (arrow head) and the raphal ridge (ra); note pointed micropylar area (S174179, Vale de Água sample 141). i) Seed surface of seed in (5d) showing the raised outlines of the undulate anticlinal walls of the exotestal cells. Scale bars = 250 µm (a–e, g, h); 125 µm (f, i). in Extinct Taxa Of Exotestal Seeds Close To Austrobaileyales And Nymphaeales From The Early Cretaceous Of Portugal

Text-fig. 5. Reyispermum parvum gen. et sp. nov. seeds from the Early Cretaceous Vale de Água locality, Portugal; Synchrotron radiation X-ray tomographic microscopy (SRXTM, volume renderings). a) Holotype (S174178; Vale de Agua sample 141) in lateral view showing shape and cell pattern; remains of mounting media (¤). b) Cut volume rendering of seed (cut at yz0553) showing the slightly raised tissue immediately adjacent to the lower edge of the hilum (arrow head) and palisade-shaped cells of exotesta. c) Apical view of seed showing hilar depression (hi), position of micropylar slit (mi) and the slightly raised raphal ridge (ra). d) Seed in lateral view showing raised tissue immediately adjacent to the lower edge of the hilum (arrow head) (S174495, Vale de Água sample 300). e) Cut volume rendering (cut at yz0500) of the seed in (5d) showing the raised tissue (arrow head) immediately adjacent to the lower edge of the hilum and sclerenchyma cells of exotesta. f) Detail of seed in (5d) showing micropylar slit (mi), hilum (hi) and raised tissue (arrow head) immediately adjacent to the lower edge of the hilum. g, h) Seed in lateral view (g) and view towards raphe (h) showing seed shape, the raised tissue below hilum (arrow head) and the raphal ridge (ra); note pointed micropylar area (S174179, Vale de Água sample 141). i) Seed surface of seed in (5d) showing the raised outlines of the undulate anticlinal walls of the exotestal cells. Scale bars = 250 µm (a–e, g, h); 125 µm (f, i).

opencc-by-4.0Aug 2018View details →
zenodo40/100

Text-fig. 1. Gastonispermum portugallicum gen. et sp. nov. seeds from the Early Cretaceous Famalicão locality (sample 025), Portugal; Synchrotron radiation X-ray tomographic microscopy (SRXTM, volume renderings). Note remains of mounting media on several seeds (¤). a) Seed in oblique view showing seed shape, the slightly raised raphal ridge and the position of hilum (hi) and micropyle (mi) on the raphal side of the seed (S170218). b, c) Seeds in lateral view (b, S170234; c, S175095). d–f) Holotype (S174820); seed in lateral view (d) and cut volume rendering (e, f) through the median plane of the seed showing palisade-shaped sclerenchyma cells of exotesta and remains of embryo (emb) and surrounding nutritive tissue (e, cut between yz0440-0530; f, cut between slices yz440-480). g) Hilum (hi) and micropyle (mi) of seed in (1a) showing the Y-shaped micropylar slit in the outer integument. h) Cut volume rendering through the median plane of the seed (cut at yz0492) showing seed coat mainly composed of palisade-shaped cells of the exotesta (S174435). i) Seed surface showing the raised outlines of the undulate anticlinal walls of the exotestal cells (S175045). Scale bars = 500 µm (a–e); 250 µm (g); 125 µm (f, i). in Extinct Taxa Of Exotestal Seeds Close To Austrobaileyales And Nymphaeales From The Early Cretaceous Of Portugal

Text-fig. 1. Gastonispermum portugallicum gen. et sp. nov. seeds from the Early Cretaceous Famalicão locality (sample 025), Portugal; Synchrotron radiation X-ray tomographic microscopy (SRXTM, volume renderings). Note remains of mounting media on several seeds (¤). a) Seed in oblique view showing seed shape, the slightly raised raphal ridge and the position of hilum (hi) and micropyle (mi) on the raphal side of the seed (S170218). b, c) Seeds in lateral view (b, S170234; c, S175095). d–f) Holotype (S174820); seed in lateral view (d) and cut volume rendering (e, f) through the median plane of the seed showing palisade-shaped sclerenchyma cells of exotesta and remains of embryo (emb) and surrounding nutritive tissue (e, cut between yz0440-0530; f, cut between slices yz440-480). g) Hilum (hi) and micropyle (mi) of seed in (1a) showing the Y-shaped micropylar slit in the outer integument. h) Cut volume rendering through the median plane of the seed (cut at yz0492) showing seed coat mainly composed of palisade-shaped cells of the exotesta (S174435). i) Seed surface showing the raised outlines of the undulate anticlinal walls of the exotestal cells (S175045). Scale bars = 500 µm (a–e); 250 µm (g); 125 µm (f, i).

opencc-by-4.0Aug 2018View details →
zenodo40/100

Text-fig. 6. Reyispermum parvum gen. et sp. nov. seeds from the Early Cretaceous Vale de Água locality, Portugal (a, b, d, e: sample 141, c: sample 300); Synchrotron radiation X-ray tomographic microscopy (SRXTM, orthoslices). a) Longitudinal orthoslice (yz0563) through the median plane of the seed (holotype, S174178) showing the palisade-shaped cells of exotesta and collapsed inner parts of seed coat, raised exotestal tissue (arrow head) immediately adjacent to the lower edge of the hilum (hi), micropyle (mi) and remains of cellular nutritive tissue. b) Longitudinal orthoslice (xz0659) through the micropylar region perpendicular to the median plane showing the exotestal tissue surrounding the transverse micropyle slit (mi). c) Longitudinal orthoslice (yz0500) through the median plane of the seed (S175095) showing raised tissue (arrow head) immediately adjacent to the lower edge of the hilum (hi), micropyle (mi) and poorly preserved cells of the seed coat. d) Longitudinal orthoslice (xz0810) through middle part of seed perpendicular to the median plane (S174178) showing seed coat and remains of cellular nutritive tissue. e) Tangential and longitudinal orthoslice (xz0162) through the seed coat of holotype (S174178) showing thickened, undulate cell walls of exotesta (ex) and the short, thin-walled cells of tegmen (te) with a finely striate wrinkled surface. Scale bars = 250 µm (a, c, d); 125 µm (b, e). in Extinct Taxa Of Exotestal Seeds Close To Austrobaileyales And Nymphaeales From The Early Cretaceous Of Portugal

Text-fig. 6. Reyispermum parvum gen. et sp. nov. seeds from the Early Cretaceous Vale de Água locality, Portugal (a, b, d, e: sample 141, c: sample 300); Synchrotron radiation X-ray tomographic microscopy (SRXTM, orthoslices). a) Longitudinal orthoslice (yz0563) through the median plane of the seed (holotype, S174178) showing the palisade-shaped cells of exotesta and collapsed inner parts of seed coat, raised exotestal tissue (arrow head) immediately adjacent to the lower edge of the hilum (hi), micropyle (mi) and remains of cellular nutritive tissue. b) Longitudinal orthoslice (xz0659) through the micropylar region perpendicular to the median plane showing the exotestal tissue surrounding the transverse micropyle slit (mi). c) Longitudinal orthoslice (yz0500) through the median plane of the seed (S175095) showing raised tissue (arrow head) immediately adjacent to the lower edge of the hilum (hi), micropyle (mi) and poorly preserved cells of the seed coat. d) Longitudinal orthoslice (xz0810) through middle part of seed perpendicular to the median plane (S174178) showing seed coat and remains of cellular nutritive tissue. e) Tangential and longitudinal orthoslice (xz0162) through the seed coat of holotype (S174178) showing thickened, undulate cell walls of exotesta (ex) and the short, thin-walled cells of tegmen (te) with a finely striate wrinkled surface. Scale bars = 250 µm (a, c, d); 125 µm (b, e).

opencc-by-4.0Aug 2018View details →
dryad40/100

Avian cranial evolution is influenced by shape interactions between hard and soft tissue traits

Open the record for dataset details and reuse information.

publicNov 2025View details →
zenodo36/100

Metabolic rate data and code for: Intra-specific differences in metabolic rates shape carbon stable isotope trophic discrimination factors of muscle tissue in the common teleost Eurasian perch (Perca fluviatilis)

<p>Metabolic rate data and code for: Intra-specific differences in metabolic rates shape carbon stable isotope trophic discrimination factors of muscle tissue in the common teleost Eurasian perch (Perca fluviatilis)</p> <p>&nbsp;</p> <p>The raw data and R-code used to calculate SMR used in the analysis.&nbsp;</p>

opencc-by-4.0Jan 2021View details →
zenodo36/100

Small brains: Body shape constrains tissue allocation to the central nervous system in ant-mimicking spiders

<p>In Batesian mimicry, mimetic traits are not always as convincing as predicted by theory &ndash; in fact, inaccurate mimicry with only a superficial model resemblance is common and taxonomically widespread. The &lsquo;selection trade-offs hypothesis&rsquo; proposes a life-history trade-off between accurate mimetic traits and one or more vital biological functions. Here, using an accurate myrmecomorphic (ant-mimicking) jumping spider species, <em>Myrmarachne smaragdina</em>, we investigate how myrmecomorphic modifications to the body shape impact the internal anatomy in a way that could be functionally limiting. Specifically, via X-ray micro-computed tomography (microCT), we quantify how the spider&rsquo;s constricted prosoma, which emulates the head and thorax of ants, impacts the size of the central nervous system (CNS) and the venom glands. We found that, relative to their whole-body mass, the CNS&nbsp;of the ant-mimicking jumping spider was smaller when compared with a relatively closely related non-mimic jumping spider, indicating that some trade-off between mimic accuracy and size of neural anatomy, as articulated by the &lsquo;selection trade-offs hypothesis&rsquo;, is a possibility. Our explorative evidence enables and encourages broader investigation of how variable mimic accuracy impacts the neuroanatomy in ant mimics as a direct test of the &lsquo;selection trade-offs hypothesis&rsquo;.&nbsp;</p>

opencc-by-4.0Dec 2023View details →
ClinicalTrials.gov36/100

Tissue Expander Breast Reconstruction Study on Breast Volume and Shape Change

ClinicalTrials.gov study NCT01222390. IPD Sharing: Not stated. Countries: 1. Publications: 3.

restrictedIPD-UNDECIDEDFeb 2026View details →
zenodo32/100

CellMet: Extracting 3D shape metrics from cells and tissues

<p>This dataset supports the manuscript title "CellMet: Extracting 3D shape metrics from cells and tissues". It contains segmented images (mask.tif) of severals tissues. </p>

opencc-by-4.0Nov 2024View details →
zenodo28/100

Post-resolution macrophages shape long-term tissue immunity and integrity in a mouse model of Streptococcus pneumonia.

Open the record for dataset details and reuse information.

opencc-by-4.0Feb 2024View details →
zenodo28/100

Text-fig. 4. SRXTM images of Miranthus elegans gen. et sp. nov.; Mira locality, Portugal. a, b: Transverse (a) and longitudinal (b) sections of flower showing the ovary wall (ow) and numerous ovules (ov) borne on the mushroom-shaped central globose placenta (pl, blue); placenta shown as a voltex rendering added to orthoslices; note the large openings in the floral tissue (asterisks) interpreted as schizogenous secretory cavities. c, d: Longitudinal (c) and transverse (d) sections of flower (c, volume rendering cut between orthoslice yz0970-1005; d, volume rendering cut between orthoslice xy0780-0820) showing semiinferior ovary (ow, ovary wall) with sepals inserted at the rim of the hypanthium, central column (cc) with mushroom-shaped globose placenta (pl) bearing numerous ovules (ov). Specimens, Mira 100-S153146 (a, b), Mira 100-S170155 (c, d, holotype). Scale bars = 600 µm (a–d). in Early Flowers Of Primuloid Ericales From The Late Cretaceous Of Portugal And Their Ecological And Phytogeographic Implications

Text-fig. 4. SRXTM images of Miranthus elegans gen. et sp. nov.; Mira locality, Portugal. a, b: Transverse (a) and longitudinal (b) sections of flower showing the ovary wall (ow) and numerous ovules (ov) borne on the mushroom-shaped central globose placenta (pl, blue); placenta shown as a voltex rendering added to orthoslices; note the large openings in the floral tissue (asterisks) interpreted as schizogenous secretory cavities. c, d: Longitudinal (c) and transverse (d) sections of flower (c, volume rendering cut between orthoslice yz0970-1005; d, volume rendering cut between orthoslice xy0780-0820) showing semiinferior ovary (ow, ovary wall) with sepals inserted at the rim of the hypanthium, central column (cc) with mushroom-shaped globose placenta (pl) bearing numerous ovules (ov). Specimens, Mira 100-S153146 (a, b), Mira 100-S170155 (c, d, holotype). Scale bars = 600 µm (a–d).

opencc-by-4.0Dec 2021View details →
zenodo28/100

Text-fig. 12. Silutanispermum kvacekiorum gen. et sp. nov. seeds from the Early Cretaceous Famalicão locality (sample 025), Portugal; Synchrotron radiation X-ray tomographic microscopy (SRXTM, orthoslices). a) Longitudinal orthoslice (yz1170) through the median plane of the seed (S170238) in the micropylar region showing exotestal cells lining the micropylar slit (mi) and hilum (hi); note the well-preserved mesotestal cells (me). b) Longitudinal orthoslice (xz0805) of seed perpendicular to the median plane through the micropylar region showing the transverse micropylar slit (mi) lined by radiating exotestal cells; note abundant mesotestal cells (me). c) Transverse orthoslice (xy0768) through seed below hilum and micropyle showing exotesta (ex) and mesotesta (me) that is strongly developed along the raphe (ra) (S174352). d) Transverse orthoslice (xy2113) through middle of the seed showing well-preserved cellular nutritive tissue with empty cells; note that the raphe (ra) is enclosed in mesotestal tissue (S174352). e) Longitudinal orthoslice (yz0970) through seed coat showing exotesta (ex) of tall palisade-shaped cells and thick mesotesta (me) of low cells (S174352). Scale bars = 500 µm (a, c, d); 250 µm (b); 125 µm (e). in Extinct Taxa Of Exotestal Seeds Close To Austrobaileyales And Nymphaeales From The Early Cretaceous Of Portugal

Text-fig. 12. Silutanispermum kvacekiorum gen. et sp. nov. seeds from the Early Cretaceous Famalicão locality (sample 025), Portugal; Synchrotron radiation X-ray tomographic microscopy (SRXTM, orthoslices). a) Longitudinal orthoslice (yz1170) through the median plane of the seed (S170238) in the micropylar region showing exotestal cells lining the micropylar slit (mi) and hilum (hi); note the well-preserved mesotestal cells (me). b) Longitudinal orthoslice (xz0805) of seed perpendicular to the median plane through the micropylar region showing the transverse micropylar slit (mi) lined by radiating exotestal cells; note abundant mesotestal cells (me). c) Transverse orthoslice (xy0768) through seed below hilum and micropyle showing exotesta (ex) and mesotesta (me) that is strongly developed along the raphe (ra) (S174352). d) Transverse orthoslice (xy2113) through middle of the seed showing well-preserved cellular nutritive tissue with empty cells; note that the raphe (ra) is enclosed in mesotestal tissue (S174352). e) Longitudinal orthoslice (yz0970) through seed coat showing exotesta (ex) of tall palisade-shaped cells and thick mesotesta (me) of low cells (S174352). Scale bars = 500 µm (a, c, d); 250 µm (b); 125 µm (e).

opencc-by-4.0Aug 2018View details →
geo24/100

Inflammation-dependent differentiation of two distinct regulatory T cell populations in the visceral adipose tissue shapes systemic metabolism [RNA-seq II]

GEO Series GSE235420. Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenMar 2024View details →
geo24/100

A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment.

GEO Series GSE128855. Mus musculus. 35 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenMar 2019View details →
geo24/100

Inflammation-dependent differentiation of two distinct regulatory T cell populations in the visceral adipose tissue shapes systemic metabolism

GEO Series GSE235421. Mus musculus. 62 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2024View details →
geo24/100

The tissue-resident regulatory T cell pool is shaped by transient multi-tissue migration and a conserved residency program. scRNA-Seq profiling of mouse tissue Tregs with TCR sequencing and CITE-Seq

GEO Series GSE266111. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing; Other.

openGEO-OpenMay 2024View details →

ScienceDex guides

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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.

Compare curated datasets

Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record