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8 results for “topological data analysis”
Topological Data Analysis of Monopoles in U(1) Lattice Gauge Theory — Data Release
<div>This release contains data used to prepare the publication <a href="https://arxiv.org/abs/2403.07739">X. Crean, J. Giansiracusa and B. Lucini, Topological Data Analysis of Monopoles in U(1) Lattice Gauge Theory (2024)</a>. There exists an <a href="https://doi.org/10.5281/zenodo.10806185">accompanying software release</a> that explains in detail how to extract and use the compressed data files on a Linux distribution (or compatible environment).</div>
A Topological Data Analysis Perspective on Non-Covalent Interactions in Relativistic Calculations - supplementary information
<p>This repository contains the supplementary data to the following publication:</p> <p>"A Topological Data Analysis Perspective on Non-Covalent Interactions in Relativistic Calculations", by the same authors.</p>
Dissecting glial scar formation by spatial point pattern and topological data analysis
<p>These data were generated by the Laboratory of Neurovascular Interactions (https://elalilab.com/) at University Laval (Quebec, Canada), and reported in "Dissecting glial scar formation by spatial point pattern and topological data analysis". </p> <p>Please refer to the Open Science Framework (OSF) repository (https://osf.io/3vg8j/) or GitHub (https://github.com/elalilab/GlialScar_PPA-TDA_2022) to see the processing pipeline.</p> <p><strong>AUTHORS</strong><br> Manrique-Castano, Daniel; Bhaskar, Dhananjay; ElAli, Ayman</p> <p><strong>KEYWORDS</strong><br> Stroke, cerebral ischemia, brain injury, glial scar, reactive astrocytes, reactive microglia, </p> <p><br> <strong>1. STUDY DESCRIPTION </strong> <br> This research provides a quantitative analysis of reactive glia and glial scar formation in a mouse model of cerebral ischemia. The dataset in this repository consists of raw widefield microscopy images from healthy and ischemic animals. </p> <p><strong>2. EXPERIMENTAL CONDITIONS</strong><br> Six-month-old C57BL/6 mice were subjected to 30 minutes of cerebral ischemia by middle cerebral artery occlusion (MCAO). Brains were harvested at 5, 15, and 30 days post-ischemia (DPI) (see 10.5281/zenodo.3559570). 5 sham animals were included as controls. The full protocol for brain harvesting is available at 10.17504/protocols.io.4r3l27q5pg1y/v1. Brain sections were stained with NeuN, Gfap, and Iba1 antibodies to detect neurons and reactive glia after injury. Full protocol available at 10.17504/protocols.io.yxmvmk94og3p/v1 <br> <br> <strong>3. FILE DESCRIPTION</strong></p> <p><strong>- GT5X_Gfap_Iba1_NeuN.rar: </strong>Contain widefield (5x magnification) .tif images grouped by animals (5-7 images per animal; see research article for further details). The images were taken with the following parameters.</p> <p>Objective: Fluar 5x/0.25 M27<br> Scaling per pixel: 1.300 x 1.300 µm<br> Bit depth: 16 bit </p> <p>Stainings:<br> Neun Channel AF647; Excitation 653; Emission 668; Exposure 3 s<br> IBA1 Channel AFCy3; Excitation 458; Emission 561; Exposure 4 s<br> GFAP Channel AF488; Excitation 493; Emission 517; Exposure 1 s<br> DAPI Channel AF405; Excitation 353; Emission 465; Exposure 50 ms</p> <p>We used a FIJI script to pre-process the original .czi files. The script is shared in the GitHub repository under the name GT_Exp2_5x_GenerateTiffs.jim.</p> <p><strong>- GT10X_Gfap_Iba1_NeuN.rar:</strong> Contain a single widefield (10x magnification) .tif image per animal at the level of the MCA territory (see research article for further details). The images were taken with the following parameters.</p> <p>Objective: ECM paln-NeoFluar 10x/0.30 M27<br> Scaling per pixel: 0.45 x 0.45 µm<br> Bit depth: 16 bit </p> <p>Stainings:<br> Neun Channel AF647; Excitation 653; Emission 668; Exposure 200 ms<br> IBA1 Channel AFCy3; Excitation 458; Emission 561; Exposure 250 ms<br> GFAP Channel AF488; Excitation 493; Emission 517; Exposure 100 ms<br> DAPI Channel AF405; Excitation 353; Emission 465; Exposure 10 ms</p> <p><br> We used a FIJI script to pre-process the original .czi files. The script is shared in the GitHub repository under the name GT_Exp2_10x_GenerateTiffs.jim.<br> <br> For 5x and 10x images, the following naming strings apply:</p> <p>GT5x: Research project identifier indicating the magnification<br> M01(n): Animal ID<br> 5D(n): Days post-ischemia. 0D refers to healthy (naive) animals. <br> Scene1(n): Bregma level. Scene 1 corresponds to the most anterior area sampled, while Scene 6 or 7 is the most posterior.</p> <p><strong>- PointPatterns_10x.rds: </strong>2D point patterns of GFAP, IBA1, and NeuN generated by the r-package <em>spatstat</em>. The observation window comprises a horizontal ROI from the ventricular area to the outer border of the dorsolateral cerebral cortex. The point patterns were generated from the files and coordinates contained in the <strong>QupathProjects_10x.rar</strong> file in this repository. To reproduce the generation of point patterns please refer to the associated GitHub repository (https://github.com/elalilab/Stroke_GlialScar_PPA-TDA). </p> <p><strong>- PointPatterns_5x.rds: </strong>2D point patterns of GFAP, IBA1, and NeuN generated by the r-package <em>spatstat</em>. The observation window comprises the ischemic hemisphere. The point patterns were generated from the files and coordinates contained in the <strong>QupathProjects_5x.rar</strong> file in this repository. To reproduce the generation of point patterns please refer to the associated GitHub repository (https://github.com/elalilab/Stroke_GlialScar_PPA-TDA). </p> <p><strong>- QupathProjects_5x.rar: </strong>QuPath project folder for 5x images (GT5X_Gfap_Iba1_NeuN.rar). Each subfolder (per animal) contains the necessary files to import annotations (alignment to the Allen Brain Atlas) generated by ABBA (https://biop.github.io/ijp-imagetoatlas/). Please see the research article for further details. </p> <p><strong>**NOTE** </strong>Gfap, Iba1, and NeuN folders contain raw .tsv data originated by QuPath (cell counting). These folders are read in the R processing pipeline to extract the coordinates of each cell. Please make sure the whole folder is in the R working directory. The file "project.qpproj" in each folder opens the QuPath project in QuPath and reads the classifiers and data folders. Each folder also contains "_Alignement.json" and "_Registration_json" files generated during the alignment and annotation procedures in ABBA. However, when the route of the source images is changed, the plugin does not allow rerouting, and the files are of no practical use. The issue has been reported to the ABBA Github repository. </p> <p><strong>- QupathProjects_10x.rar:</strong> QuPath project folder for 10x images (GT5X_Gfap_Iba1_NeuN.rar). The folder contains the necessary files to import annotations (Alignment to the Allen Brain Atlas) generated by ABBA (https://biop.github.io/ijp-imagetoatlas/). Please see the research article for further details. </p> <p><strong>**NOTE** </strong>Gfap, Iba1, NeuN, and DAPI folders contain raw .tsv data originated by QuPath (cell counting). These folders are read in the R processing pipeline to extract the coordinates of each cell. Please make sure the whole folder is in the R working directory. The file "project.qpproj" opens the QuPath project in QuPath and reads the classifiers and data folders. </p>
Topological data analysis of vortices in the magnetically-induced current density in LiH molecule
<p>This is the accompanying data for the paper titled "Topological data analysis of vortices in the magnetically-induced current density in LiH molecule" by Malgorzata Olejniczak and Julien Tierny</p>
Analysis of the DNA topology in T47D-MTVL cells by Hi-C data
GEO Series GSE147627. Homo sapiens. 1 samples. Type: Other.
Data from: Topological data analysis of biological aggregation models
We apply tools from topological data analysis to two mathematical models inspired by biological aggregations such as bird flocks, fish schools, and insect swarms. Our data consists of numerical simulation output from the models of Vicsek and D'Orsogna. These models are dynamical systems describing the movement of agents who interact via alignment, attraction, and/or repulsion. Each simulation time frame is a point cloud in position-velocity space. We analyze the topological structure of these point clouds, interpreting the persistent homology by calculating the first few Betti numbers. These Betti numbers count connected components, topological circles, and trapped volumes present in the data. To interpret our results, we introduce a visualization that displays Betti numbers over simulation time and topological persistence scale. We compare our topological results to order parameters typically used to quantify the global behavior of aggregations, such as polarization and angular momentum. The topological calculations reveal events and structure not captured by the order parameters.
Data from: Topological data analysis of biological aggregation models
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FIGURE. Phylogram of Tolypocladium generated from Maximum likelihood analysis of ITS, SSU and LSU sequence data. Purpureocillium lilacinum (CBS 284.36) was selected as an outgroup taxon. The tree topology of the ML analysis was similar to the BI. Maximum likelihood bootstrap values greater than 75 and Bayesian posterior probabilities over 0.90 were indicated above the nodes. The scale bar indicates 0.006 changes. The new species was in blue. in Yunnan-Guizhou Plateau: a mycological hotspot
FIGURE. Phylogram of Tolypocladium generated from Maximum likelihood analysis of ITS, SSU and LSU sequence data. Purpureocillium lilacinum (CBS 284.36) was selected as an outgroup taxon. The tree topology of the ML analysis was similar to the BI. Maximum likelihood bootstrap values greater than 75 and Bayesian posterior probabilities over 0.90 were indicated above the nodes. The scale bar indicates 0.006 changes. The new species was in blue.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.