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Myocardial ultrastructure of human heart failure with preserved ejection fraction
<p>These transmission electron micrographs were obtained from endocardial biopsies of patients with heart failure and preserved ejection fraction, or from non-failling control myocardium. The myocardium is from the right side of the ventricular septum. Images are shown at various magnification levels indicated in the title of the image. Images with titles: HH_DM+ or HH_DM-; Mixed_DM+ or Mixed_DM-; OB_DM+ or OB_DM-; or NF_DM+ or NF_DM- show examples from the primary groups, HH represents HFpEF patients with primarily hypertensive hypertrophic heart disease and the least obesity; OB represents HFpEF patients with primarily severe obesity and the least hypertensive hypertrophic disease; Mixed matches obesity and hypertensive hypertrophic heart disease in HFpEF patients to levels obsserved in the HH and OB groups, and NF is non-failing controls. </p> <p>Additional images are shown for NF, HH, OB, and Mixed from the remaining patients in this study are provided at two magnification levels. These are provided as individual pictures as well. </p> <p> </p>
Figure 8 in Ultrastructure of the prosomal gland complex in unfed larvae of the fresh-water mite Limnesia maculata (Müller, 1776) (Acariformes, Limnesiidae)
Figure 8 Organization of the labyrinth of coxal glands in unfed larvaeL. maculata.TEM. a – Central portion of the labyrinth with a conspicuous central lumen filled with various membranous and granular structures. Scale bar – 2 μm; b – Portion of the labyrinth with a collapsed lumen penetrated by microvilli. Scale bar – 2 μm; c – Basal lamina penetrating between the gland cells at their base (arrow). Scale bar – 0.5µζ; d – Portion of the convoluted labyrinth showing semi-circled mutual invagination of the gland cells (arrow). Scale bar – 1 μm; e – The apical cell contact with hardly distinguishable septate junction (arrow). Note axial filaments within microvilli (arrowheads). Scale bar – 0.5 μm. gl – glycogen; gll – gland lumen; m – mitochondria; mg – midgut; mt – microtubules; mv – microvilli; n – nucleus; nu – nucleolus; rb – residual body; rer – rough endoplasmic reticulum.
Figure 1 in Ultrastructure of the prosomal gland complex in unfed larvae of the fresh-water mite Limnesia maculata (Müller, 1776) (Acariformes, Limnesiidae)
Figure 1 Podocephalic glands in unfed larvaeL. maculatain sagittal sections. TEM. a – Nearly axial section showing two medial glands located one after another as well as pharynx and chelicera. Scale bar – 20 μm; b – Section slightly apart from the axial line showing medial glands and podocephalic canal.Arrow indicates long extensions of the duct-forming cells flanking lateral lacunas of the intra-alveolar lumen. Scale bar – 10 μm; c – Section through the region of the origin of leg I showing the lateral and the ventral glands as well as the terminal bladder of the coxal gland in a nearly collapsed condition. Scale bar – 20 μm. amg – anterior medial gland; bl – bladder; br – brain; ch – chelicera; hem – hemocyte; ial – intra-alveolar lumen; lg – lateral gland; legI – leg I; ms – muscles; pc – podocephalic canal; ph – pharynx; pmg – posterior medial gland; schs – subcheliceral space; vg – ventral gland.
Figure 14. Trilobatus sacculifer and Globigerinoidesella fistulosa protuberance ultrastructure. A in Systematic taxonomy of the Trilobatus sacculifer plexus and descendant Globigerinoidesella fistulosa (planktonic foraminifera)
Figure 14. Trilobatus sacculifer and Globigerinoidesella fistulosa protuberance ultrastructure. A, Trilobatus sacculifer (Brady, 1877); B–G, Globigerinoidesella fistulosa (Schubert, 1910). A, ODP Site 1115, Woodlark Basin, western Pacific; 10H/04/ 127–129 cm (incipient protuberance with surface texture continuous from chamber). B, C, F, G, ODP Site 1115, Woodlark Basin, western Pacific; 10H/04/127–129 cm (A, numerous spine holes present, many pores obscured/distorted; B, surface texture change towards protuberance ends with blocky thick calcite obscuring pores; F, cross-sectional view of broken protuberance, showing hollow interior; G, cross-sectional view of broken protuberance, showing hollow interior); D, E, ODP Site 1115, Woodlark Basin, western Pacific; 11H/04/25–27 cm (D, surface texture change towards protuberance ends; blocky thick calcite obscuring pores; E, left protuberance marked by change in wall texture at protuberance end, right protuberance has all original surface texture obscured). Scale bars = 20 Lm.
Fig. 3 in Hrabeiella Periglandulata (Annelida: "Polychaeta") Do Apparent Differences In Chaetal Ultrastructure Indicate The Existence Of Several Species In Europe?
Fig. 3. Hrabeiellaperiglandulata, chaetae, SEMmicrograph (thewormswerefixedinetha- nol, thespecimenfromSpainfixedinBouinsolution): A = anteriorpartofbodywiththree rowsofchaetaeofaspecimenfromBakonyMts, Hungary (ventro-lateralview), B = lateral chaetaeinthesecondrow (specimenfromBrno, CzechRepublic), C = chaetaeinthesecond row (ventralview, specimenfromVěncováhora (locustypicus), CzechRepublic), D = cha-
Fig. 1 in Hrabeiella Periglandulata (Annelida: "Polychaeta") Do Apparent Differences In Chaetal Ultrastructure Indicate The Existence Of Several Species In Europe?
Fig. 1. Distributionof Hrabeiellaperiglandulata inEuropebasedonrecordspreviouslypublished (circles) orreportedinthisstudy (squares).
Fig. 4 in Hrabeiella Periglandulata (Annelida: "Polychaeta") Do Apparent Differences In Chaetal Ultrastructure Indicate The Existence Of Several Species In Europe?
Fig. 4. SEMmicrographsof Hrabeiellaperiglandulata chaetaeshowingadifferentshape (the wormswerefixedonlyinethanol): A = LateralchaetaeofaspecimenfromHungary. B = Lateralchaetaeinthethirdrowofaspecimenfromnorth-westernCzechia. C = Ventral chaetaeofthelastrowsofaspecimenfromHungary (BakonyMts). D = Chaetaeinthefifth
Fig. 3. A in Sperm ultrastructure in three different families of weakly electric fishes (Teleostei: Gymnotiformes)
Fig. 3. A: Spermatozoon of Eigenmannia trilineata (SEM), h = sperm head, arrow = flagellum, double arrow = midpiece, m = mitochondrion; B, E: Spermatozoa of E. trilineata in longitudinal section (TEM) showing ovoid nucleus (n) with flocculent chromatin, centriolar arrangement (dc= distal centriole, pc= proximal centriole), and elongate mitochondria (m), v = vesicles; C: Flagella of spermatozoa of E. trilineata in cross sections (TEM) showing axonemal or flagellar fins (af); D: Midpiece of spermatozoa of E. trilineata in cross section (TEM) showing presence of vesicles (v) and mitochondria (m), and flagellar axoneme (a) with electron-lucent tubules of each peripheral doublet. Scale bars = 1µm.
Fig. 2. A in Sperm ultrastructure in three different families of weakly electric fishes (Teleostei: Gymnotiformes)
Fig. 2. A: Spermatozoon of Gymnotus aff. carapo (SEM), h = sperm head, arrow = flagellum, double arrow = midpiece; B-C: Spermatozoa of G.aff. carapo in longitudinal section (TEM) showing spherical nucleus (n), centriolar complex and flagellum (f) lateral to the nucleus (n), double nuclear fossa (double arrow), centriolar arrangement (dc= distal centriole, pc= proximal centriole), mitochondria (m), and presence of vesicles (v) in the posterior portion of midpiece, cc = cytoplasmic canal; D: Flagella of spermatozoa of G. aff. carapo in cross section (TEM) showing electron-lucent tubules of each peripheral doublet (arrow); E: Midpiece of spermatozoon of G.aff. carapo in longitudinal section (TEM) showing short cytoplasmatic canal (cc) and vesiclular arrangement (v). Scale bars = 1µm.
Fig. 1 in Histological And Ultrastructural Studies On The Intestine Of Guntea Loach, Lepidocephalichthys Guntea (Cypriniformes, Cobitidae)
Fig. 1. Photomicrographs of various regions of the intestine of Lepidocephalichthys guntea by scanning electron microscopy (SEM) as well as transmission electron microscopy (TEM) and histological sections stained with Delafield's Haematoxylin-Eosin (HE) and Mallory's triple (MT) stain: a — anterior intestine consists of mucosa (M) with numerous finger like projections (V) toward the lumen (L), submucosa (solid arrows), muscularis (ML) and serosa (arrow heads) (MT) ×100; b — middle intestine exhibits blunt projections lined with tightly packed columnar epithelial cells (CEC) and mucous cells (broken arrows). The submucosa (SM) is distinguished from mucosa (M) by basement membrane (BM) and made up of connective tissue, collagen fibres and blood vessels (solid arrows) forming lamina propria (LP). Note the presence of apical top plate (arrow heads) over the mucosal border (HE) ×400; c — higher magnification of middle intestine showing mucosa (M) packed with CEC having conspicuous nuclei (N) and top plate (arrow heads). Broken arrow marks secreted mucin from mucous cell (HE) ×1000; d — luminal surface of the middle intestine provided with prominent microridges (arrow heads) represent the apical surface of CEC. Note the presence of mucous cells (solid arrows) in between CEC and mucin mass (broken arrows) over CEC (SEM) ×3500; e — folds (V) of middle intestine provided with columnar epithelial cells having numerous microvilli (MV) apically and basally located nuclei (N). Note the presence of scattered mucous cells (broken arrows) in between columnar epithelial cells. Solid arrows indicate blood vessels with erythrocytes (TEM) ×570; f — mucosa of middle intestine showing CEC with microvilli (MV) and nucleus (N) connected with neighbouring cells by tight junctions (broken arrows). Cytoplasm contains tuft of mitochondria (solid arrows), lysosome (arrow head) and lipid droplets (LD). Note the presence of MC and BV (TEM) ×2550.
Fig. 1 in Histological, Topographical And Ultrastructural Organization Of Different Cells Lining The Olfactory Epithelium Of Red Piranha, Pygocentrus Nattereri (Characiformes, Serrasalmidae)
Fig. 1. Photomicrographs of the olfactory epithelium of Pygocentrus nattereri by scanning electron microscopy (SEM) and histological architecture stained with Delafield's Haematoxylin-Eosin (HE) and Mallory's triple (MT) stain. A — oval shaped olfactory rosette showing olfactory lamellae (OL) radiating from median raphe (R). Note tongue shaped structure (arrow heads) on the apical end of the lamellae (SEM) ×50. B — sensory olfactory epithelium (OEP) lined with receptor cells. Note the presence of blood vessels (BV) in the central core (CC) which is distinguished from OEP by basement membrane (BM). Arrow heads indicate basal cells above BM (MT) ×400. C — higher magnification of OEP showing a large number of primary receptor cells (RC) with conspicuous nuclei (N), secondary recptor cells (broken arrows), microvillous cells (MV) intermingled with supporting cells (SC). Note the presence of BV in CC and BC (arrow heads) near CC. Solid arrow indicates the axons of secondary RC communicate to CC (MT) ×1000. D — OEP exhibiting cylindrical RC with knob like vesicles (black arrow heads), ciliated supporting cells (solid arrows), non-ciliated supporting cells (white arrow heads) and BC above CC. Broken arrows mark the cilia of supporting cells on the epithelial surface (HE) ×400. E — tuft of receptor cells (RC) in between supporting cells (SC) (SEM) ×4000. F — dendrite patches of RC (broken arrows) and microvillous cells (solid arrows) in between stratified epithelial cells (SEC). Note the opening of mucous cells (arrow heads) in between SEC (SEM) ×2500.
Fig. 2 in Histological, Topographical And Ultrastructural Organization Of Different Cells Lining The Olfactory Epithelium Of Red Piranha, Pygocentrus Nattereri (Characiformes, Serrasalmidae)
Fig. 2. Photomicrographs of the olfactory epithelium of P. nattereri by scanning electron microscopy (SEM), transmission electron microscopy (TEM) and histological features stained with Mallory's triple (MT) stain. A — transitional zone between sensory epithelium (SE) with receptor cells (solid arrows) and non-sensory epithelium (NSE) having a series of mucous cells (MC) (Broken arrows), labyrinth cells (LC) and stratified epithelial cells (arrow heads). Olfactory epithelium separated from central core (CC) by a basement membrane (BM) (MT) ×400. B — surface of non-sensory epithelium showing densely arranged ciliated supporting cells (solid arrows) encircled the non-ciliated supporting cells (SC) with adhering mucin mass (arrow heads). Note the opening of MC (broken arrows) in between SC (SEM) ×4500. C — dendrite of receptor cell (RC) emerging out from basal body (broken arrow). Note microtubules of rod (solid arrow) parallel arranged (TEM) ×5000. D —nuclei of receptor cells (N) showing dispersed heterochromatin (arrow heads). Note the presence of mitochondria (solid arrows) adjacent to nucleus (TEM) ×500. (E) Showing cisterns of rough endoplasmic reticulum (rER) (arrow heads) encircling nucleus (solid arrow). Note Golgi apparatus (broken arrow) adjacent to rER (TEM) ×4000. F — OEP lined with microvillous cells (MV), mucous cell (MC) and supporting cell (broken arrow) (TEM) ×2100. G — microvillous cells exhibiting abundant ribosomes (broken arrows) and extended mitochondria (arrow heads). Solid arrow indicates nucleus (TEM) ×5000. H — axons (broken arrows) of receptor cells run parallel on both sides of basal cells (solid arrow) (TEM) ×5000.
Fig. 3 in Histological, Topographical And Ultrastructural Organization Of Different Cells Lining The Olfactory Epithelium Of Red Piranha, Pygocentrus Nattereri (Characiformes, Serrasalmidae)
Fig. 3. Photomicrographs of the olfactory epithelium of P. nattereri by transmission electron microscopy (TEM) and scanning electron microscopy (SEM). A — olfactory epithelium (OEP showing mucous cell (MC) having granules, microvillous cell (arrow head), labyrinth cell (broken arrow) and vesicular cytoplasm of supporting cell (solid arrow) (TEM) ×2100. B — flat surface ciliated supporting cell (solid arrow) provided with plenty of kinocilia (arrow heads) showing microtubular pattern (broken arrows). Note large number of mitochondria within the cytoplasm of supporting cells (TEM) ×5000. C — non-sensory olfactory epithelium (OEP) comprised of MC filled with large granules and supporting cells (solid arrows) (TEM) ×2100. D — basal cells provided with conspicuous lobular nuclei (N) having dense nucleolus (solid arrow). Note the presence of small vesicles (arrow head) adjacent the nucleus and rough endoplasmic reticulum (rER) (broken arrows) (TEM) ×2500. E — showing nuclear division of basal cells provided with dense nucleus (solid arrows). Broken arrows indicate mature nucleus of basal cells (TEM) ×2500. F — showing labyrinth cells (solid arrow) with conspicuous folding encircled by compactly arranged stratified epithelial cells (SEC). Note the presence of MC (broken arrows) in between SEC and mucin droplets (arrow heads) over SEC (SEM) ×4500. G — surface epithelium of raphe provided with packed SEC having labyrinth pattern microridges. Note the presence of opening of MC (solid arrows) and mucin droplets (arrow heads) over SEC (SEM) ×4500. H — raphe showing oval and elongated nuclei (N) of Stratified epithelial cells. Note the presence of rER (solid arrows) and vesicles (broken arrows) adjacent to nucleus (TEM) × 2500.
Text-fig. 14. Dendrograms of studied taxa based on enamel ultrastructure characters. a: dendrogram based on all three enamel types; b: dendrogram based on enamel type I. in The Ultrastructure Of The Tooth Enamel Of Small Equus Of The "Tarpan" Group And Their Possible Phylogenetic Connections
Text-fig. 14. Dendrograms of studied taxa based on enamel ultrastructure characters. a: dendrogram based on all three enamel types; b: dendrogram based on enamel type I.
Text-fig. 13. Enamel ultrastructure of I1, Equus hydruntinus (Kabazi 2). a: vertical sections, scale bar = 100 Μm; b: horizontal and vertical arrangement of prisms in the HSB structure, scale bar = 10 Μm; c: unstructured PLEX enamel at the end of the root, scale bar = 100 Μm. in The Ultrastructure Of The Tooth Enamel Of Small Equus Of The "Tarpan" Group And Their Possible Phylogenetic Connections
Text-fig. 13. Enamel ultrastructure of I1, Equus hydruntinus (Kabazi 2). a: vertical sections, scale bar = 100 Μm; b: horizontal and vertical arrangement of prisms in the HSB structure, scale bar = 10 Μm; c: unstructured PLEX enamel at the end of the root, scale bar = 100 Μm.
Text-fig. 12. HSB of first and second upper incisors of Equus przewalskii (Chornobyl Exclusion Zone). a, b: vertical section, scale bar = 100 Μm; c: horizontal cross-section, scale bar = 50 Μm. in The Ultrastructure Of The Tooth Enamel Of Small Equus Of The "Tarpan" Group And Their Possible Phylogenetic Connections
Text-fig. 12. HSB of first and second upper incisors of Equus przewalskii (Chornobyl Exclusion Zone). a, b: vertical section, scale bar = 100 Μm; c: horizontal cross-section, scale bar = 50 Μm.
Text-fig. 9. Enamel ultrastructure of M1-2, Equus hydruntinus (Kabazi 2). a, b: type I; c, d: type II. in The Ultrastructure Of The Tooth Enamel Of Small Equus Of The "Tarpan" Group And Their Possible Phylogenetic Connections
Text-fig. 9. Enamel ultrastructure of M1-2, Equus hydruntinus (Kabazi 2). a, b: type I; c, d: type II.
Text-fig. 8. Enamel ultrastructure of M1, Equus przewalskii (Chornobyl Exclusion Zone). a, b: enamel row, scale bar = 100 and 20 Μm respectively; c: type I and III, scale bar = 20 Μm; d–f: first type enamel arrangement, scale bar d = 10, e = 3 Μm and f = 2 Μm; g, h: prisms of TZ, scale bar = 50 and 30 Μm respectively; i: type II near OES, scale bar = 20 Μm. in The Ultrastructure Of The Tooth Enamel Of Small Equus Of The "Tarpan" Group And Their Possible Phylogenetic Connections
Text-fig. 8. Enamel ultrastructure of M1, Equus przewalskii (Chornobyl Exclusion Zone). a, b: enamel row, scale bar = 100 and 20 Μm respectively; c: type I and III, scale bar = 20 Μm; d–f: first type enamel arrangement, scale bar d = 10, e = 3 Μm and f = 2 Μm; g, h: prisms of TZ, scale bar = 50 and 30 Μm respectively; i: type II near OES, scale bar = 20 Μm.
Text-fig. 4. Enamel ultrastructure of M1-2, Equus gmelini (Myrne). a: enamel row, scale bar = 30 Μm; b: type I and III, scale bar = 20 Μm; c: type II near OES border, scale bar = 2 Μm. in The Ultrastructure Of The Tooth Enamel Of Small Equus Of The "Tarpan" Group And Their Possible Phylogenetic Connections
Text-fig. 4. Enamel ultrastructure of M1-2, Equus gmelini (Myrne). a: enamel row, scale bar = 30 Μm; b: type I and III, scale bar = 20 Μm; c: type II near OES border, scale bar = 2 Μm.
Text-fig. 10. Enamel ultrastructure of I1 (a) and I2 (b, c), Equus gmelini, tarpan (Myrne). a: vertical section; b, c: horizontal cross-section, scale bar = 250 and 100 Μm respectively. in The Ultrastructure Of The Tooth Enamel Of Small Equus Of The "Tarpan" Group And Their Possible Phylogenetic Connections
Text-fig. 10. Enamel ultrastructure of I1 (a) and I2 (b, c), Equus gmelini, tarpan (Myrne). a: vertical section; b, c: horizontal cross-section, scale bar = 250 and 100 Μm respectively.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.