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Dataset results
14 results for “valve-in-valve”
Data from: Numerical models for assessing the risk of leaflet thrombosis post-transcatheter aortic valve-in-valve implantation
<p>Leaflet thrombosis has been suggested as the reason for the reduced leaflet motion in cases of hypoattenuated leaflet thickening of bioprosthetic aortic valves. This work aimed to estimate the risk of leaflet thrombosis in two post-ViV configurations, using five different numerical approaches. Realistic ViV configurations were calculated by modeling the deployments of the latest version of transcatheter aortic valve devices (Medtronic Evolut PRO, Edwards SAPIEN 3) in the surgical Sorin Mitroflow. Computational fluid dynamics simulations of blood flow followed the dry models. Lagrangian and Eulerian measures of near-wall stagnation were implemented by particle and concentration tracking, respectively, to estimate the thrombogenicity and to predict the risk locations. Most of the numerical approaches indicate on a higher leaflet thrombosis risk in the Edwards SAPIEN 3 device because of its intra-annular implantation. The Eulerian approaches estimated high-risk locations in agreement with the WSS separation points. On the other hand, the Lagrangian approaches predicted high-risk locations at the proximal regions of the leaflets matching the low WSS magnitude regions of both TAVI models and reported clinical and experimental data. The proposed methods can help optimizing future designs of transcatheter aortic valves with minimal thrombotic risks.</p>
Renato® Transcatheter Valve-in-Valve System Multicenter Registry Trial (China)
ClinicalTrials.gov study NCT07174531. IPD Sharing: NO. Countries: 1. Publications: 1.
Polish Transcatheter Transfemoral Mitral Valve-in-Valve Implantation (Mitral ViV) Registry
ClinicalTrials.gov study NCT05625607. IPD Sharing: NO. Countries: 1. Publications: 1.
Comparison of Allegra vs Sapien Transcatheter Aortic Valves in Valve-In-Valve Indication
ClinicalTrials.gov study NCT06049654. IPD Sharing: Not stated. Countries: 2. Publications: 7.
Polish Transcatheter Aortic Valve-in-Valve Implantation (ViV-TAVI) Registry
ClinicalTrials.gov study NCT03361046. IPD Sharing: NO. Countries: 1. Publications: 5.
Randomized Trial of Transcatheter Valve-in-Valve vs Redo Surgery for Bioprosthetic Mitral Dysfunction
ClinicalTrials.gov study NCT04402931. IPD Sharing: NO. Countries: 1. Publications: 0.
Data from: Numerical models for assessing the risk of leaflet thrombosis post-transcatheter aortic valve-in-valve implantation
Open the record for dataset details and reuse information.
Portico Valve-in-Valve Retrospective Registry
ClinicalTrials.gov study NCT05002088. IPD Sharing: NO. Countries: 4. Publications: 0.
PARTNER 3 Trial - Aortic Valve-in-Valve
ClinicalTrials.gov study NCT03003299. IPD Sharing: NO. Countries: 2. Publications: 0.
The Asia-Pacific Mitral & Tricuspid Valve-in-Valve/Valve-in-Ring Registry (AP ViV Registry)
ClinicalTrials.gov study NCT07058935. IPD Sharing: NO. Countries: 6. Publications: 0.
INSPIRIS RESILIA Aortic Valve, Valve-in-Valve Surveillance Study
ClinicalTrials.gov study NCT04902053. IPD Sharing: NO. Countries: 1. Publications: 0.
The Asia-Pacific Mitral & Tricuspid Valve-in-Valve/Valve-in-Ring Registry
ClinicalTrials.gov study NCT07296016. IPD Sharing: NO. Countries: 1. Publications: 0.
Prizvalve® Transcatheter Valve-in-Valve Implantation Exploratory Study
ClinicalTrials.gov study NCT05652062. IPD Sharing: Not stated. Countries: 1. Publications: 0.
One-year safety and efficacy profile of transcatheter aortic valve-in-valve implantation with the portico system
<p>Dataset from Casenghi M, Gorla R, Popolo Rubbio A, De Marco F, Brambilla N, Agnifili M, Testa L, Bedogni F. One-year safety and efficacy profile of transcatheter aortic valve-in-valve implantation with the portico system. Catheter Cardiovasc Interv. 2021 Jul 1;98(1):E145-E152. doi: 10.1002/ccd.29353. Epub 2020 Nov 6. PMID: 33155757.</p> <p>Abstract</p> <p><strong>Objective: </strong>This study sought to investigate the procedural and mid-term outcomes of transcatheter aortic valve implantation for failed surgical bioprostheses (TAVI-ViV) with Portico device.</p> <p><strong>Background: </strong>Limited evidence coming from early experience on Portico system does not allow to fully assess safety and efficacy of this device in this ViV patients.</p> <p><strong>Methods: </strong>From January 2016 up to June 2019, 56 consecutive patients undergoing TAVI-ViV with Portico were prospectively included in our institutional TAVI database.</p> <p><strong>Results: </strong>The prevalent mechanism of failure was stenosis (58.9%); true internal diameter (ID) was <21 mm in 71.4% of cases. Device success rate were 69.6% with 14 (25%) patients showing a residual gradient ≥20 mmHg, 2 (3.6%) a PVL ≥ moderate and 1 (1.8%) required a second THV implantation due to device embolization. At 1-year follow-up 5 patients (8.9%) died whereas moderate SVD was reported in 2 (3.6%). Patients with a post-procedural mean gradient ≥20 mmHg showed a significantly higher rate of CV hospitalization (21.4% vs. 2.4%, p = .02) whereas no differences in procedural and 1-year outcomes were noticed according to true ID diameter or degeneration mode. Chimney stenting (ChT) was performed in 23 (41%) patients without significant differences in procedural and 1-year outcomes compared to non-ChT group.</p> <p><strong>Conclusions: </strong>TAVI-ViV with Portico valve was associated with good procedural and 1-year outcomes, even in patients with features of high procedural and anatomical complexity.</p>
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