Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
154
datasets available to search
ShareScore release 0.7.1
Dataset results
154 results for “vitamin B12”
Vitamin_B12_related_genes_and_FASTA_sequences
<p>These two files are related to a submitted research paper on the study of a 7-year metagenomic time series carried monthly in a northwestern Mediterranean coastal site (SOLA, Banyuls-sur-Mer, FRANCE) :</p> <p><em>Seasonal succession of different vitamin B12 biosynthesis pathways and producers in coastal marine microbial communities. </em></p> <p>This study focuses on prokaryotes involved in vitamin B12 metabolism (biosynthesis, transport, remodeling) and on the metabolic pathways involved in these processes.</p> <p>The dataset in <strong>.xlsx</strong> format represents the abundance table of all the genes associated with 82 KEGGs involved in vitamin B12 metabolism, and the file in <strong>.fasta</strong> format corresponds to the FASTA sequences associated with these genes.</p>
ACF database on the B12 vitamin outcomes from the MANGO trial
<p>This dataset contains the variables used in the analysis of the B12 vitamin outcomes of the MANGO trial carried out in Burkina Faso between 2016 and 2018.</p>
Data from : Genomic Sequence of Klebsiella pneumoniae IIEMP-3, a Vitamin B12-Producing Strain from Indonesian Tempeh
<p>Klebsiella pneumoniae strain IIEMP-3, isolated from Indonesian tempeh, is a vitamin B<sub>12</sub>-producing strain that exhibited a different genetic profile from pathogenic isolates. Here we report the draft genome sequence of strain IIEMP-3, which may provide insights on the nature of fermentation, nutrition, and immunological function of Indonesian tempeh.</p>
Vitamin B12 deficiency anaemia and gestational diabetes mellitus: a two-sample Mendelian randomization study
Open the record for dataset details and reuse information.
Flow cytometry data for "Vitamin B12 conveys a protective advantage to phycosphere-associated bacteria at high temperatures"
<p>More details—including the analysis pipeline—are available in the GitHub repository: <a href="http://github.com/maggimars/bactB12">https://github.com/maggimars/bactB12</a>. </p> <p>Direct link to analysis pipeline interactive document: <a href="https://maggimars.github.io/bactB12/Flow_Cytometry_Analysis.html">https://maggimars.github.io/bactB12/Flow_Cytometry_Analysis.html</a></p> <p> </p> <p> </p>
Vitamin B12, Neurodevelopment and Growth in Nepal
ClinicalTrials.gov study NCT02272842. IPD Sharing: YES. Countries: 1. Publications: 9.
Transcobalamin receptor antibodies in autoimmune vitamin B12 central deficiency
<p>Vitamin B12 is critical for hematopoiesis and myelination. Deficiency can cause neurologic deficits including loss of coordination and cognitive decline. However, diagnosis relies on vitamin B12 measurement in the blood which may not accurately reflect levels in the brain. Using programmable phage display, we identified an autoantibody targeting the transcobalamin receptor (CD320) in a patient with progressive tremor, ataxia, and scanning speech. Anti-CD320 impaired cellular uptake of cobalamin (B12) <em>in vitro</em>. Despite normal serum levels, B12 was nearly undetectable in her cerebrospinal fluid (CSF). Immunosuppressive treatment and high-dose systemic B12 supplementation were associated with increased CSF B12 levels and clinical improvement. Optofluidic screening enabled rapid isolation of a patient-derived monoclonal antibody that impaired B12 transport across an <em>in vitro</em> model of the blood-brain barrier. Autoantibodies targeting the same epitope of CD320 were identified in 7 other patients with neurologic deficits of unknown etiology, in 6% of healthy controls, and in 21.4% of a neuropsychiatric lupus cohort. In 132 paired serum and CSF samples, detection of anti-CD320 in the blood predicted B12 deficiency in the brain. However, these individuals did not display any hematologic signs of B12 deficiency despite systemic CD320 impairment. Using a genome-wide CRISPR screen, we discovered that the LDL receptor serves as an alternative B12 uptake pathway in hematopoietic cells. These findings dissect the tissue-specificity of B12 transport and elucidate an autoimmune neurologic condition that may be amenable to immunomodulatory treatment and nutritional supplementation.</p>
Solution, Crystal and in-Silico Structures of the Organometallic Vitamin B12-Derivative Acetylcobalamin and of its Novel Rhodium-Analogue Acetylrhodibalamin
<p>Cartesian coordinates of all calculated structures discussed in the paper.</p>
A Trial of Vitamin B12 in Septic Shock
ClinicalTrials.gov study NCT03783091. IPD Sharing: NO. Countries: 1. Publications: 33.
Randomized Trial of Vitamin B12 in Pregnant Indian Women
ClinicalTrials.gov study NCT00641862. IPD Sharing: Not stated. Countries: 1. Publications: 8.
Vitamin B12 and Folate Administration on Homocysteine Concentrations After Nitrous Oxide Anesthesia
ClinicalTrials.gov study NCT00901394. IPD Sharing: NO. Countries: 1. Publications: 3.
Evaluation of Holotranscobalamin as an Indicator of Vitamin B12 Absorption
ClinicalTrials.gov study NCT00235573. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Transcobalamin receptor antibodies in autoimmune vitamin B12 central deficiency
Open the record for dataset details and reuse information.
Dataset for BtuB TonB-dependent transporters and BtuG surface lipoproteins form stable complexes for vitamin B12 uptake in gut Bacteroides.
<p>The dataset published here supports the work in the publication titled "BtuB TonB-dependent transporters and BtuG surface<br> lipoproteins form stable complexes for vitamin B12 uptake in gut Bacteroides." All the initial and final conformation files of the MD simulations are given along with the analyzed data presented in the manuscript.</p>
POCD: Correlations With the Gene Polymorphism and the Concentrations of Plasma Homocysteine, Folic Acid and Vitamin B12.
ClinicalTrials.gov study NCT03084393. IPD Sharing: YES. Countries: 1. Publications: 1.
Vitamin B12 Supplement to Prevent Cognitive Decline
ClinicalTrials.gov study NCT02457507. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Oral Vitamin B12 Administration for Vitamin B12 Deficiency After Total Gastrectomy
ClinicalTrials.gov study NCT00699478. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Oral Vitamin B12 as Potential Treatment of Recurrent Aphthous Stomatitis
ClinicalTrials.gov study NCT00288769. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Effect of Vitamin B12 on the Development of Sepsis, in Culture Positive Patients
ClinicalTrials.gov study NCT04008446. IPD Sharing: NO. Countries: 1. Publications: 1.
Vitamin Mix (B6, B9, B12, And Choline) For Glaucoma Patients
ClinicalTrials.gov study NCT06885827. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.