| #1 | University of Puerto Rico Medical Sciences | San Juan | University | $17.6M | 43 | 60 |
| #2 | Ponce School of Medicine | Ponce | School Of Medicine | $7.1M | 10 | 20 |
| #3 | San Juan Bautista School of Medicine | Caguas | School Of Medicine | $6.3M | 1 | 1 |
| #4 | Comprehensive Cancer Center/ Univ/Pr | San Juan | Other | $3.7M | 8 | 14 |
| #5 | University of Puerto Rico Rio Piedras | San Juan | University | $1.6M | 8 | 6 |
| #6 | Universidad Central Del Caribe | Bayamon | School Of Medicine | $1.2M | 7 | 5 |
| #7 | University of Pr Cayey University Coll | Cayey | University | $629K | 2 | 4 |
| #8 | Inter American University/Puerto Rico | San Juan | University | $405K | 1 | 1 |
| #9 | University of Puerto Rico Ponce | Ponce | University | $382.8K | 1 | 2 |
| #10 | University of Puerto Rico at Humacao | Humacao | University | $381.3K | 1 | 1 |
| #11 | Grupo Nexos Inc. | San Juan | Other | $375K | 1 | 4 |
| #12 | Sistema Universitario Ana G. Mendez, Incorporado | Carolina | Other | $366.7K | 1 | 1 |
| #13 | Lifegene-Biomarks, Inc. | San Juan | Other | $275.8K | 1 | 1 |
| #14 | University of Puerto Rico Mayaguez | Mayaguez | University | $244.9K | 1 | 1 |
| #15 | University of Puerto Rico at Aguadilla | Aguadilla | University | $182K | 1 | 1 |
| #16 | Puerto Rico Department of Health | San Juan | Other | $175K | 1 | 1 |
