Genetics at Duke University

Leads a grant in this department

43 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

1. Luftig, Micah A.

   Leads 4 awards · $2,059,807

   • 5R01CA234348-03Department: NIH department code

     Dissecting the role of EBV and P. falciparum in endemic Burkitt lymphoma pathogenesis
     $648,210

     award amount
   • 2R01CA140337-11Department: NIH department code

     Host pathways regulating Epstein-Barr virus-mediated B cell growth transformation
     $494,354

     award amount
   • 2R01DE025994-06Department: NIH department code

     Defining the Mechanisms of Epstein-Barr Virus Persistence and Recurrence
     $467,077

     award amount
   • 5T32CA009111-43Department: NIH department code

     Viral Oncology Training Grant
     $450,166

     award amount

2. Smith, Clare Margaret

   Leads 1 award · $1,449,000

   • 1DP2GM146458-01Department: NIH department code

     Dissecting the genetic basis of protective immunity to tuberculosis in diverse hosts
     $1,449,000

     award amount

3. Heitman, Joseph

   Leads 3 awards · $1,351,483

   • 2R01AI039115-24Department: NIH department code

     Impact of RNAi and unisexual reproduction on Cryptococcus evolution, drug resistance, and pathogenesis
     $642,774

     award amount
   • 5R01AI050113-17Department: NIH department code

     Structure, function, and evolution of the Cryptococcus MAT locus
     $507,459

     award amount
   • 1R21AI159397-01Department: NIH department code

     Implications of mycoviral infection in Talaromyces marneffei: an analysis of human patient samples, RNAi, and hypermutation
     $201,250

     award amount

4. Marchuk, Douglas A.

   Leads 1 award · $1,310,712

   • 5P01NS092521-07Department: NIH department code

     Signaling Aberrations and Cerebral Cavernous Malformation Pathogenesis
     $1,310,712

     award amount

5. Silver, Debra

   Leads 4 awards · $1,263,875

   • 5T32HD040372-20Department: NIH department code

     Training Program in Developmental & Stem Cell Biology
     $361,015

     award amount
   • 5R01NS110388-04Department: NIH department code

     Distal mRNA localization and translation in neural stem cells of the developing brain
     $356,145

     award amount
   • 5R01NS083897-08Department: NIH department code

     Essential requirements of Eif4a3 in brain development and disease
     $345,465

     award amount
   • 1R21HD104514-01A1Department: NIH department code

     Cell biological and proteomic investigation of pathogenic DDX3X missense mutations during neurogenesis
     $201,250

     award amount

6. Heaton, Nicholas S

   Leads 2 awards · $1,205,390

   • 5R01HL142985-04Department: NIH department code

     Loss of cellular identity after influenza virus infection and effects on pulmonary function
     $609,414

     award amount
   • 5R01AI137031-03Department: NIH department code

     The pathogenic effects of epithelial cells surviving direct influenza virus infection
     $595,976

     award amount

7. Coyne, Carolyn B

   Leads 2 awards · $1,110,244

   • 7R01AI145828-03Department: NIH department code

     Innate immune signaling in placental antiviral defenses
     $707,744

     award amount
   • 7R01AI081759-11Department: NIH department code

     Enterovirus Infection of Polarized Intestinal Cells
     $402,500

     award amount

8. Chi, Jen-Tsan Ashley

   Leads 3 awards · $1,006,455

   • 5R01GM124062-04Department: NIH department code

     Biochemical and functional investigation of the novel enzymatic activities of MESH1
     $391,323

     award amount
   • 3R01GM124062-04S1Department: NIH department code

     Biochemical and functional investigation of the novel enzymatic activities of MESH1
     $375,495

     award amount
   • 5R21AI149205-02Department: NIH department code

     The regulation dephosphorylated-CoA-capped RNA and innate immunity by MESH1
     $239,637

     award amount

9. Valdivia, Raphael H

   Leads 2 awards · $939,602

   • 5R01AI134891-04Department: NIH department code

     Functional characterization of early Chlamydia effectors
     $484,647

     award amount
   • 5R01AI142376-04Department: NIH department code

     Genetic analysis of mucin utilization by Akkermansia muciniphila and its impact on host physiology
     $454,955

     award amount

10. Coers, Joern

    Leads 2 awards · $916,702

    • 5R01AI139425-03Department: NIH department code

      Human GBPs in cell-autonomous immunity to intracellular bacterial pathogens
      $458,935

      award amount
    • 5R01AI103197-08Department: NIH department code

      Interferon-inducible cell-intrinsic host defense against Chlamydia trachomatis
      $457,767

      award amount

11. Yan, Dong

    Leads 2 awards · $860,763

    • 1R56AG073994-01Department: NIH department code

      Use of C. elegans as a model to study aging-associated neurodegeneration
      $510,763

      award amount
    • 5R01NS105638-04Department: NIH department code

      Genetic study of gap junction formation and regulation in C. elegans neurons
      $350,000

      award amount

12. Matsunami, Hiroaki

    Leads 2 awards · $860,439

    • 5R01DC016224-05Department: NIH department code

      Biogenesis of olfactory G protein-coupled receptors
      $438,943

      award amount
    • 5R01DK074192-19Department: NIH department code

      Copper Homeostasis in Mammals
      $421,496

      award amount

13. Tobin, David M.

    Leads 2 awards · $824,601

    • 5R01AI130236-05Department: NIH department code

      Macrophage Reprogramming During Granuloma Formation in the Zebrafish
      $427,101

      award amount
    • 5R01AI125517-05Department: NIH department code

      Genetic dissection of angiogenesis in the tuberculous granuloma
      $397,500

      award amount

14. Boyce, Michael S

    Leads 2 awards · $819,535

    • 5R01NS111588-03Department: NIH department code

      Metabolic regulation of KLHL proteins through O-glycosylation
      $526,958

      award amount
    • 1T32GM142605-01Department: NIH department code

      Cell and Molecular Biology Training Program
      $292,577

      award amount

15. Petes, Thomas

    Leads 1 award · $706,866

    • 2R35GM118020-06Department: NIH department code

      Genetic regulation of genome stability in yeast
      $706,866

      award amount

16. Ko, Dennis Chun-Yone

    Leads 2 awards · $700,049

    • 5R01AI118903-07Department: NIH department code

      HUMAN GENETIC VARIATION REGULATING SALMONELLA HOST-PATHOGEN INTERACTIONS AND DISEASE SUSCEPTIBILITY
      $504,675

      award amount
    • 1R21AI153812-01A1Department: NIH department code

      Human Genetic Variation Regulating Transcriptional Response and Cellular Susceptibility to Influenza
      $195,374

      award amount

17. Floor, Stephen Nicholas

    Leads 1 award · $678,057

    • 1R01NS120667-01Department: NIH department code

      Cellular and molecular mechanisms underlying DDX3X syndrome
      $678,057

      award amount

18. Floyd, Scott R

    Leads 1 award · $638,289

    • 5R01NS100866-04Department: NIH department code

      Novel Targets for Stroke Intervention - Gene Discovery for Modulators of Infarction
      $638,289

      award amount

19. Jinks-Robertson, Sue

    Leads 1 award · $591,231

    • 2R35GM118077-06Department: NIH department code

      Regulation of mitotic genome stability in yeast.
      $591,231

      award amount

20. Cullen, Bryan R.

    Leads 2 awards · $559,775

    • 5R01DA046111-04Department: NIH department code

      Epitranscriptomic modification of HIV-1 transcripts: Effects of drugs of abuse
      $322,000

      award amount
    • 1R21AI157616-01Department: NIH department code

      Reversal of epigenetic silencing rescues integrase-deficient HIV-1 replication
      $237,775

      award amount

21. Sullivan, Beth A

    Leads 2 awards · $547,803

    • 5R01GM129263-03Department: NIH department code

      Centromere Function and Dicentric Chromosome Stability
      $322,000

      award amount
    • 5R21CA238758-02Department: NIH department code

      Ectopic centromere assembly in humans
      $225,803

      award amount

22. Lowe, Craig Barrett

    Leads 1 award · $470,019

    • 5R35HG011332-02Department: NIH department code

      From a Long List to Causal Variants: High-Throughput Gene Regulatory Assays in Developing Tissues
      $470,019

      award amount

23. Horner, Stacy Michelle

    Leads 1 award · $461,559

    • 1R01AI155512-01A1Department: NIH department code

      Regulation of RIG-I signaling and viral immune evasion by ufmylation
      $461,559

      award amount

24. Alspaugh, Andrew

    Leads 1 award · $411,370

    • 5T32AI052080-18Department: NIH department code

      Molecular Mycology and Pathogenesis Training Program
      $411,370

      award amount

25. Donlin, Maureen J

    Leads 1 award · $363,050

    • 7R01AI123407-06Department: NIH department code

      ROLE OF CELL WALL INTEGRITY IN ECHINOCANDIN RESISTANCE IN C. NEOFORMANS
      $363,050

      award amount

26. David, Lawrence Anthony

    Leads 1 award · $357,750

    • 5R01DK116187-04Department: NIH department code

      Personalizing prebiotic therapies that target human gut microbiota
      $357,750

      award amount

27. Scaglione, Kenneth Matthew

    Leads 1 award · $350,801

    • 5R01NS112191-03Department: NIH department code

      Novel chaperones and neurodegeneration
      $350,801

      award amount

28. He, You-Wen

    Leads 1 award · $225,803

    • 5R21CA249243-02Department: NIH department code

      The impact of genetic diversity among Akkermansia strains on the effectivenes of immune checkpoint inhibitors in cancer immunotherapies
      $225,803

      award amount

29. Ye, Lihua

    Leads 1 award · $126,892

    • 1K01DK125527-01A1Department: NIH department code

      Enteroendocrine cells sense gut bacteria and activate a gut-brain pathway
      $126,892

      award amount

30. Dolat, Lee

    Leads 2 awards · $105,687

    • 5F32AI138372-03Department: NIH department code

      Subversion of the host cell cytoskeleton and innate immunity by Chlamydia trachomatis
      $70,458

      award amount
    • 3F32AI138372-03S1Department: NIH department code

      Subversion of the host cell cytoskeleton and innate immunity by Chlamydia trachomatis
      $35,229

      award amount

31. De March, Claire A.

    Leads 1 award · $86,197

    • 5K99DC018333-02Department: NIH department code

      Understanding of G protein-coupled odorant receptors function
      $86,197

      award amount

32. Hoy, Michael

    Leads 1 award · $38,402

    • 5F31AI150120-02Department: NIH department code

      Structure-guided development of fungal specific calcineurin inhibitors
      $38,402

      award amount

33. Walsh, Stephen Charles

    Leads 1 award · $38,281

    • 5F31AI150106-02Department: NIH department code

      Defining human interferon-stimulated genes with novel functions in host defense to Chlamydia infections
      $38,281

      award amount

34. Brewer, William Jared

    Leads 1 award · $38,075

    • 1F31HL160329-01A1Department: NIH department code

      Macrophage Signaling Pathways Orchestrating Mycobacteria-induced Angiogenesis
      $38,075

      award amount

35. Kelly, Cecelia

    Leads 1 award · $38,009

    • 5F31DK121392-02Department: NIH department code

      The role of HNF4a in maintaining intestinal epithelial cell homeostasis in the presence of microbes
      $38,009

      award amount

36. Hughes, Erika Joy

    Leads 1 award · $37,966

    • 1F31AI157405-01A1Department: NIH department code

      Genetic Dissection of Mycobacterial Pathogenesis During Eicosanoid-Mediated Immunity
      $37,966

      award amount

37. Bonglack, Emmanuela

    Leads 1 award · $37,671

    • 1F31CA257621-01Department: NIH department code

      The Role and Regulation of Monocarboxylate Transporters 1 and 4 in Epstein-Barr Virus-mediated B Lymphocyte Tumorigenesis
      $37,671

      award amount

38. Priest, Shelby Jordan

    Leads 1 award · $34,763

    • 5F31AI143136-03Department: NIH department code

      Causes and Consequences of Hypermutability in Cryptococcus neoformans
      $34,763

      award amount

39. Snellings, Daniel

    Leads 1 award · $33,486

    • 5F31HL152738-02Department: NIH department code

      Investigating the Role of Somatic Mutations in Arteriovenous Malformations
      $33,486

      award amount

40. Hoye, Mariah Lawler

    Leads 1 award · $32,997

    • 3F32NS112566-02S1Department: NIH department code

      The role of an Intellectual Disability gene, DDX3X, in neural progenitors during brain development
      $32,997

      award amount

41. Bourgeois, Jeffrey

    Leads 1 award · $30,457

    • 5F31AI143147-03Department: NIH department code

      Mechanisms of methylthioadenosine signaling during Salmonella infection
      $30,457

      award amount

42. Detter, Matthew Robert

    Leads 1 award · $17,984

    • 5F30HL140871-03Department: NIH department code

      Investigating the Molecular Pathways of Cerebral Cavernous Malformation Maturation
      $17,984

      award amount

43. Gibbs, Kyle Dane

    Leads 1 award · $17,161

    • 5F31AI136313-03Department: NIH department code

      STAT3-dependent manipulation of host transcription and immune responses by Salmonella
      $17,161

      award amount