Biochemistry at Thomas Jefferson University

Leads a grant in this department

21 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

1. Hou, Ya-Ming

   Leads 4 awards · $2,207,142

   • 1R01AI164490-01Department: NIH department code

     TrmD-targeting actinobacterial natural products as next generation antibiotics
     $845,545

     award amount
   • 5R01AI139202-03Department: NIH department code

     Discovery of Gram-negative permeable chemical probes for tRNA methylation
     $684,222

     award amount
   • 5R35GM134931-02Department: NIH department code

     tRNA in codon usage
     $482,375

     award amount
   • 5R21HG011120-02Department: NIH department code

     Exploring 3Dpol for RNA sequencing in real time
     $195,000

     award amount

2. Guo, Lin

   Leads 3 awards · $1,760,000

   • 1RF1NS121143-01Department: NIH department code

     Developing RNA Oligonucleotides to Mitigate Abberant FUS Phase Transition in FTD/ALS
     $1,170,000

     award amount
   • 5R35GM138109-02Department: NIH department code

     Elucidating the Mechanism in the Regulation of RNA-binding Protein Phase Separation
     $390,000

     award amount
   • 3R35GM138109-02S1Department: NIH department code

     Elucidating the Mechanism in the Regulation of RNA-binding Phase Separation
     $200,000

     award amount

3. Merry, Diane E

   Leads 3 awards · $1,335,629

   • 5R01NS108191-04Department: NIH department code

     The AR N/C interaction in SBMA - Mechanistic role and therapeutic potential
     $466,187

     award amount
   • 5R01NS106302-03Department: NIH department code

     Determining the role of AR transcriptional function in SBMA
     $440,172

     award amount
   • 5R01NS108114-04Department: NIH department code

     The Role of the AR Interactome in SBMA
     $429,270

     award amount

4. Alnemri, Emad S

   Leads 2 awards · $1,053,331

   • 1R01AR078440-01Department: NIH department code

     Caspase-1 Activation by the Inflammasomes
     $531,919

     award amount
   • 5R01AR074564-03Department: NIH department code

     Regulation of the Cell Death Program by DFNA5
     $521,412

     award amount

5. Benovic, Jeffrey L

   Leads 2 awards · $1,035,803

   • 5R01HL142310-04Department: NIH department code

     Structural and dynamic analysis of GRK interaction with G protein-coupled receptors
     $528,803

     award amount
   • 5R35GM122541-05Department: NIH department code

     Regulation of G protein-coupled receptor signaling and trafficking
     $507,000

     award amount

6. Pomerantz, Richard T

   Leads 2 awards · $765,245

   • 5R01GM130889-04Department: NIH department code

     Structure and Function of DNA Polymerase Theta
     $387,897

     award amount
   • 5R01GM137124-03Department: NIH department code

     Mechanisms of RNA-DNA repair
     $377,348

     award amount

7. Cingolani, Gino

   Leads 2 awards · $670,692

   • 1R35GM140733-01Department: NIH department code

     Mechanism of Viral Genome Delivery into Cells
     $343,092

     award amount
   • 5R01GM122844-04Department: NIH department code

     Regulation of Nuclear Import Through Importin Alpha Isoforms
     $327,600

     award amount

8. Iacovitti, Lorraine

   Leads 1 award · $653,648

   • 5R01AI125650-05Department: NIH department code

     The Role of the De-condensed Structure of Nascent Chromatin During T Cell Differentiation
     $653,648

     award amount

9. Wedegaertner, Philip B

   Leads 2 awards · $624,000

   • 1R01GM138943-01A1Department: NIH department code

     Regulation of Mutationally Activated Gq/11
     $312,000

     award amount
   • 5R01GM132426-03Department: NIH department code

     G Protein Regulation of Golgi Structure and Function
     $312,000

     award amount

10. Deshpande, Deepak A

    Leads 1 award · $588,083

    • 5R01HL150560-02Department: NIH department code

      tRNA-derived non-coding RNAs in ASM function and in asthma
      $588,083

      award amount

11. Kirino, Yohei

    Leads 2 awards · $561,600

    • 5R01GM106047-08Department: NIH department code

      Dissection of the piRNA biogenesis pathway in germ cells
      $327,600

      award amount
    • 1R21AI151641-01A1Department: NIH department code

      Role of Toll-like receptor-induced short non-coding RNAs in innate immune response
      $234,000

      award amount

12. Temiakov, Dmitry

    Leads 1 award · $533,520

    • 5R35GM131832-03Department: NIH department code

      Molecular Mechanisms of Mitochondrial Transcription and Replication
      $533,520

      award amount

13. Pluciennik, Anna

    Leads 1 award · $390,000

    • 1R01NS118082-01A1Department: NIH department code

      Molecular mechanisms of triplet repeat instability in Huntington's disease
      $390,000

      award amount

14. Trizzino, Marco

    Leads 1 award · $390,000

    • 5R35GM138344-02Department: NIH department code

      Mechanisms of gene regulation mediated by human-specific SVA transposons
      $390,000

      award amount

15. Fouquerel, Elise

    Leads 2 awards · $378,755

    • 5R00ES027028-05Department: NIH department code

      Deciphering the mechanisms of PARP1 activity in telomere integrity
      $248,999

      award amount
    • 1R35GM142982-01Department: NIH department code

      Mechanistic insight into oxidative stress-mediated genome instability
      $129,756

      award amount

16. Winter, Edward P

    Leads 1 award · $321,360

    • 5R01GM120090-06Department: NIH department code

      Non-canonical MAPK signaling in yeast
      $321,360

      award amount

17. Mazo, Alexander M

    Leads 1 award · $319,800

    • 5R01GM075141-16Department: NIH department code

      Transcriptional Regulation by Epigenetic Factors
      $319,800

      award amount

18. Jaynes, James B

    Leads 1 award · $312,000

    • 5R01GM137062-02Department: NIH department code

      Non-canonical functions of chromatin insulators and Polycomb-group proteins
      $312,000

      award amount

19. Debler, Erik

    Leads 1 award · $261,749

    • 1R21AI154191-01A1Department: NIH department code

      Target Validation for I-BET151-Induced Differentiation in the African Trypanosome
      $261,749

      award amount

20. Deming, David

    Leads 1 award · $46,036

    • 1F31CA254208-01A1Department: NIH department code

      Inducing transcriptional reprogramming of leukemic B-cells by facilitating transcription factors binding to nascent decondensed chromatin
      $46,036

      award amount

21. Fenstermaker, Tyler Kennedy

    Leads 1 award · $11,509

    • 5F31GM128300-03Department: NIH department code

      Recruitment of transcriptional machinery following DNA replication
      $11,509

      award amount