Microbiology & Immunology at University of Pittsburgh

Leads a grant in this department

49 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

1. Vignali, Dario Aa

   Leads 2 awards · $3,223,995

   • 5P01AI108545-07Department: NIH department code

     Synergies among inhibitory receptors in tolerance, cancer & antiviral immunity
     $2,296,071

     award amount
   • 1R35CA263850-01Department: NIH department code

     Regulatory T cells and the tumor microenvironment
     $927,924

     award amount

2. Shlomchik, Mark J

   Leads 6 awards · $2,571,267

   • 5R01AI043603-21Department: NIH department code

     Murine Memory B Cell Development and Function
     $566,202

     award amount
   • 5T32AI089443-12Department: NIH department code

     Autoimmunity and Immunopathology Training Program
     $529,763

     award amount
   • 5R01AI105018-07Department: NIH department code

     Signaling and Selection in Germinal Center B Cells
     $458,535

     award amount
   • 4R37AI118841-06Department: NIH department code

     Investigating How TLR7 Activates and TLR9 Regulates Systemic Autoimmunity
     $448,989

     award amount
   • 5R01AI137132-04Department: NIH department code

     Investigating the Repertoires and Functions of T Cells that Help Autoreactive B Cells in Lupus
     $382,775

     award amount
   • 1R21AI154267-01A1Department: NIH department code

     Exploring the Role of Long Noncoding RNAs in Germinal Center B cells
     $185,003

     award amount

3. Gong, Yi-Nan

   Leads 2 awards · $1,540,992

   • 1DP2GM146320-01Department: NIH department code

     Necrotic survivors and plasma membrane integrity signaling
     $1,358,083

     award amount
   • 1R21CA259457-01Department: NIH department code

     CRL3KEAP1 complex licenses genotoxic stress-induced tumor cell death
     $182,909

     award amount

4. Ndhlovu, Lishomwa C

   Leads 1 award · $1,213,831

   • 5R01AI142662-03Department: NIH department code

     Effects of HIV SIV on unconventional T cells in immunity to M. tuberculosis in pre adolescents
     $1,213,831

     award amount

5. Smithgall, Thomas E.

   Leads 4 awards · $1,162,021

   • 5R01AI152677-02Department: NIH department code

     Chemical Biology of HIV-1 Nef
     $619,290

     award amount
   • 5R01CA233576-03Department: NIH department code

     Precision Targeting of Myeloid Src-family Kinases in Acute Myelogenous Leukemia
     $435,632

     award amount
   • 3R01CA233576-03S1Department: NIH department code

     Precision Targeting of Myeloid Src-family Kinases in Acute Myelogenous Leukemia
     $80,868

     award amount
   • 3R01CA233576-02S1Department: NIH department code

     Precision Targeting of Myeloid Src-family Kinases in Acute Myelogenous Leukemia
     $26,231

     award amount

6. Deluca, Neal A.

   Leads 3 awards · $1,149,035

   • 2R56AI030612-26Department: NIH department code

     Virus-cell interactions affecting HSV gene expression
     $618,032

     award amount
   • 5T32AI049820-17Department: NIH department code

     Viral Persistence and Pathogenesis
     $335,378

     award amount
   • 1R21AI156065-01Department: NIH department code

     Modulation and Utilization of RNA Polymerase III by Herpes Simplex Virus
     $195,625

     award amount

7. Ambrose, Zandrea

   Leads 2 awards · $1,141,441

   • 5R01AI134195-05Department: NIH department code

     Influence of SIV replication on TB progression and immunity
     $945,816

     award amount
   • 1R21OD030204-01A1Department: NIH department code

     Pathogenesis of HIV and HBV Co-Infection in a Humanized Mouse Model
     $195,625

     award amount

8. Bomberger, Jennifer Melinda

   Leads 2 awards · $957,508

   • 5R33HL137077-05Department: NIH department code

     Impact of virome on microbial communities in the respiratory tract
     $566,258

     award amount
   • 5R01HL142587-03Department: NIH department code

     Polymicrobial interactions in the respiratory tract
     $391,250

     award amount

9. Das, Jishnu

   Leads 1 award · $950,000

   • 1U01HG012041-01Department: NIH department code

     Linking genome variation to transcriptional network dynamics in human B cells
     $950,000

     award amount

10. Moore, Patrick S.

    Leads 1 award · $931,373

    • 5R35CA197463-06Department: NIH department code

      Discovery and Characterization of New Human Cancer Viruses
      $931,373

      award amount

11. Gao, Shou-Jiang

    Leads 3 awards · $915,912

    • 5R01CA096512-15Department: NIH department code

      Cell model for KSHV Infection and Genetic Manipulation
      $391,250

      award amount
    • 2R01CA124332-13A1Department: NIH department code

      Regulation of KSHV replication by N6-methyladenosine (m6A)
      $334,965

      award amount
    • 5R01CA213275-06Department: NIH department code

      KSHV microRNAs in tumor invasion and angiogenesis
      $189,697

      award amount

12. Borghesi, Lisa

    Leads 3 awards · $895,285

    • 5R01AI145064-03Department: NIH department code

      B cell population structure in mouse and man
      $386,730

      award amount
    • 1S10OD030396-01Department: NIH department code

      ZellScanner ONE
      $286,800

      award amount
    • 5R21AI142744-02Department: NIH department code

      Unbiased visualization of human ASC subsets
      $221,755

      award amount

13. Finn, Olivera J

    Leads 1 award · $821,873

    • 5R35CA210039-06Department: NIH department code

      Immunoprevention and immunosurveillance of human non-viral cancers
      $821,873

      award amount

14. Ehrt, Sabine

    Leads 1 award · $807,595

    • 5R01AI143788-03Department: NIH department code

      Development of a Self Inactivating, Highly Effective TB Vaccine
      $807,595

      award amount

15. Kane, Lawrence P.

    Leads 3 awards · $786,106

    • 5R01AI138504-04Department: NIH department code

      Regulation of T cell activation and exhaustion by Tim-3
      $388,425

      award amount
    • 5R01GM136148-02Department: NIH department code

      Regulation of PI3K by PIK3IP1/TrIP
      $323,749

      award amount
    • 3R01AI138504-04S1Department: NIH department code

      Regulation of T cell activation and exhaustion by Tim-3
      $73,932

      award amount

16. Guo, Haitao

    Leads 2 awards · $778,377

    • 5R01AI134818-05Department: NIH department code

      The Role of HBeAg in HBV Persistence
      $395,844

      award amount
    • 2R01AI110762-06Department: NIH department code

      Molecular Mechanisms of HBV cccDNA Formation
      $382,533

      award amount

17. Scanga, Charles A.

    Leads 1 award · $772,812

    • 1R01AI155345-01A1Department: NIH department code

      Preventing TB with intravenous BCG in SIV-infected macaques
      $772,812

      award amount

18. Mariuzza, Roy A

    Leads 1 award · $711,977

    • 5R01AI144422-03Department: NIH department code

      Structure, Function and Mechanistic Analysis of LAG3
      $711,977

      award amount

19. Mc Clane, Bruce A

    Leads 2 awards · $704,925

    • 5R01AI019844-38Department: NIH department code

      Mechanism of action of C. perfringens enterotoxin
      $469,800

      award amount
    • 5R21AI148911-02Department: NIH department code

      NanI sialidase: Effects on Clostridium perfringens enterotoxin activity and contributions to C. perfringens type F infection
      $235,125

      award amount

20. Diamond, Michael S

    Leads 1 award · $634,610

    • 5R01AI150214-02Department: NIH department code

      A new mechanism of antiviral activity of 2'-5' Oligoadenylate Synthetase 1
      $634,610

      award amount

21. Lee, Nara

    Leads 3 awards · $625,541

    • 5R21AI151073-02Department: NIH department code

      Characterizing the Molecular Mode of Action of EBV Noncoding RNA EBER1
      $234,750

      award amount
    • 1R21AI163246-01Department: NIH department code

      Examining the Dynamic Architecture of the Influenza Virus Genome
      $195,625

      award amount
    • 1R21AI156162-01Department: NIH department code

      To employ gamma-peptide nucleic acid oligomers to interfere with viral replication
      $195,166

      award amount

22. Das, Jishnu

    Leads 1 award · $470,125

    • 1DP2AI164325-01Department: NIH department code

      Using three-dimensional protein networks to uncover immuno-modulatory molecular phenotypes in infectious disease
      $470,125

      award amount

23. Meisel, Marlies

    Leads 1 award · $453,324

    • 1R01DK130897-01Department: NIH department code

      Systemic immunoregulatory consequences of bacterial translocation during health and disease
      $453,324

      award amount

24. Coyne, Carolyn B

    Leads 1 award · $438,653

    • 5R01AI150151-02Department: NIH department code

      The Role of FcRn in Echovirus Entry and Pathogenesis
      $438,653

      award amount

25. Glorioso, Joseph C.

    Leads 1 award · $398,001

    • 5R01CA222804-04Department: NIH department code

      Arming Oncolytic HSV Vectors to Induce Anti-GBM Immune Responses in Syngeneic Mice
      $398,001

      award amount

26. Schmidt, Martin C

    Leads 1 award · $396,167

    • 5R01GM046443-28Department: NIH department code

      Mechanisms of glucose signal transduction in yeast
      $396,167

      award amount

27. Lu, Binfeng

    Leads 1 award · $396,116

    • 1R01CA254274-01A1Department: NIH department code

      Study of the IL-33-driven immune cell organization underpinning responses to immune checkpoint blockade cancer therapy
      $396,116

      award amount

28. Morel, Penelope Anne

    Leads 1 award · $388,425

    • 5R01AI125513-04Department: NIH department code

      Akt controls alternative splicing in T helper call fate decisions
      $388,425

      award amount

29. Lakdawala, Seema S.

    Leads 1 award · $381,870

    • 5R01AI139063-04Department: NIH department code

      Visualization of Influenza Viral RNA Assembly
      $381,870

      award amount

30. Richardson, Anthony R.

    Leads 1 award · $378,450

    • 5R01AI093613-11Department: NIH department code

      The Metabolic Evolution of Staphylococcus aureus
      $378,450

      award amount

31. Bina, James Edward

    Leads 1 award · $375,995

    • 5R01AI132460-04Department: NIH department code

      Environmental adaptation by Vibrio cholerae
      $375,995

      award amount

32. Li Song

    Leads 1 award · $355,409

    • 5R01CA239716-03Department: NIH department code

      Study of Interleukin 33 as a new immunotherapy of lung cancer
      $355,409

      award amount

33. Binder, Robert J

    Leads 1 award · $354,892

    • 5R01CA233803-02Department: NIH department code

      CD91 and cancer immunosurveillance
      $354,892

      award amount

34. Li, Jihong

    Leads 1 award · $234,750

    • 5R21AI146492-02Department: NIH department code

      Evaluating NanH Sialidase Contributions to Growth, Sporulation and Toxin Action for C. perfringens Type F Food Poisoning Strains
      $234,750

      award amount

35. Hawse, William Francis

    Leads 1 award · $233,620

    • 5R21AI144558-02Department: NIH department code

      Defining how T cells measure the strength of T cell receptor signals
      $233,620

      award amount

36. Hinterleitner, Reinhard

    Leads 1 award · $195,060

    • 1R21AI163721-01Department: NIH department code

      Gut mucosal type-2 immunity to parasitic infections
      $195,060

      award amount

37. Joglekar, Alok

    Leads 1 award · $159,124

    • 5R03DK127447-02Department: NIH department code

      Identification of the cognate epitopes of autoreactive T cells in Type 1 Diabetes
      $159,124

      award amount

38. D'cruz, Louise M.

    Leads 1 award · $75,990

    • 1R03AI151545-01A1Department: NIH department code

      Generation of an Atf3 reporter mouse line to interrogate immune cell-adipocyte crosstalk
      $75,990

      award amount

39. Gocher-Demske, Angela Marie

    Leads 1 award · $68,562

    • 5F32CA247004-02Department: NIH department code

      Production of Interferon Gamma by Regulatory T Cells Mediates Response to Immunotherapy
      $68,562

      award amount

40. Vignali, Paolo Dario Angelo

    Leads 1 award · $51,036

    • 5F30CA247034-02Department: NIH department code

      Tumor-infiltrating terminally exhausted CD8+ T cells augment the suppressive microenvironment within solid tumor
      $51,036

      award amount

41. Cosgrove, Haylee

    Leads 1 award · $46,036

    • 5F31AR077989-02Department: NIH department code

      The Roles and Regulation of TLR7 in Systemic Lupus Erythematosus
      $46,036

      award amount

42. Depeaux, Kristin Leigh

    Leads 1 award · $46,036

    • 5F31CA247129-02Department: NIH department code

      Causes and consequences of oncolytic virus infection of non-tumoral cells in cancer immunotherapy
      $46,036

      award amount

43. Frisch, Andrew

    Leads 1 award · $46,036

    • 1F31CA257760-01Department: NIH department code

      Metabolically improving the generation, function, and persistence of therapeutic T cells for the treatment of cancer
      $46,036

      award amount

44. Grebinoski, Stephanie

    Leads 1 award · $46,036

    • 5F31AI147638-03Department: NIH department code

      Investigating a disintegrin and metalloproteinase-mediated Neuropilin 1 cleavage in autoimmune diabetes
      $46,036

      award amount

45. Peralta, Ronal

    Leads 1 award · $46,036

    • 1F31AI152429-01A1Department: NIH department code

      Immunological Synapse Restricted Metabolic Reprogramming Drives Driectional Cytokine Synthesis
      $46,036

      award amount

46. White, Tristan Augustus Lenora

    Leads 1 award · $46,036

    • 5F31AI152320-02Department: NIH department code

      AKT phosphorylation of hnRNPA1 modulates T cell fate and function
      $46,036

      award amount

47. Watson, McLane

    Leads 1 award · $40,654

    • 5F31AI149971-02Department: NIH department code

      Lactate transporter MCT1 is required for the high suppressive function of tumor infiltrating regulatory T cells
      $40,654

      award amount

48. Selzer, Ari

    Leads 1 award · $30,036

    • 1F31CA265294-01Department: NIH department code

      Allosteric Modulators of Src-family Kinases for Acute Myeloid Leukemia
      $30,036

      award amount

49. Xiao, Gutian

    Leads 1 award · $16,770

    • 1R21CA259706-01Department: NIH department code

      Faithful mouse modeling of human lung cancer
      $16,770

      award amount