Pediatrics at Washington University in St. Louis

Leads a grant in this department

59 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

1. Perlmutter, David H

   Leads 1 award · $1,848,657

   • 5P01DK096990-10Department: NIH department code

     New Therapies for Liver Fibrosis and Hyperproliferation in Alpha1-AT Deficiency
     $1,848,657

     award amount

2. Cooper, Jonathan D

   Leads 1 award · $1,604,586

   • 1RM1NS132962-01Department: NIH department code

     Systems-Level Approach to Neuronopathic Lysosomal Storage Disorders
     $1,604,586

     award amount

3. Rivera-Spoljaric, Katherine

   Leads 1 award · $1,487,809

   • 1UG3OD035521-01Department: NIH department code

     Childhood Allergy and the NeOnatal Environment in St Louis (CANOE-STL) and the Impact of Wheezing Illnesses on Neurocognitive Development of Preschool Children
     $1,487,809

     award amount

4. Debosch, Brian Jesse

   Leads 3 awards · $1,467,376

   • 5R01HL147968-04Department: NIH department code

     Treating secondary cardiomyopathies by mimicking the adaptive hepatic glucose fasting response
     $626,492

     award amount
   • 1R01DK131009-01A1Department: NIH department code

     Leveraging arginase biology against metabolic disease
     $436,856

     award amount
   • 5R01DK126622-03Department: NIH department code

     Leveraging glucose transport and the adaptive fasting response to modulate hepatic metabolism
     $404,028

     award amount

5. Dougherty, Joseph D

   Leads 1 award · $1,260,000

   • 5P50HD103525-04Department: NIH department code

     Washington University Intellectual and Developmental Disabilities Research Center
     $1,260,000

     award amount

6. Bubeck Wardenburg, Juliane

   Leads 3 awards · $1,215,351

   • 5R01AI159677-03Department: NIH department code

     Development of human adaptive immunity to Staphylococcus aureus
     $628,474

     award amount
   • 5T32HL125241-09Department: NIH department code

     Pediatric Cardiovascular and Pulmonary Research Training Program
     $352,874

     award amount
   • 1R21AI176063-01Department: NIH department code

     ADAM10 polymorphism in susceptibility to S. aureus disease
     $234,003

     award amount

7. Dickson, Patricia I

   Leads 3 awards · $1,116,357

   • 9U01NS134354-05Department: NIH department code

     Washington University School of Medicine Undiagnosed Diseases Network Clinical Site
     $623,335

     award amount
   • 3U01NS134354-05S1Department: NIH department code

     Washington University School of Medicine Undiagnosed Diseases Network Clinical Site
     $311,000

     award amount
   • 5T32GM139799-03Department: NIH department code

     Postdoctoral Training Program in Genomic Medicine
     $182,022

     award amount

8. Dharnidharka, Vikas R.

   Leads 1 award · $987,185

   • 1U01CA275304-01A1Department: NIH department code

     Understanding the immune response changes to clinical interventions for Epstein-Barr virus infection prior to lymphoma development in children after organ transplants (UNEARTH)
     $987,185

     award amount

9. Sykes, Stephen Matthew

   Leads 2 awards · $923,703

   • 1R01CA273127-01A1Department: NIH department code

     Determining the Role and Targeting potential of Serine Metabolism in aggressive sub-types of Acute Myeloid Leukemia
     $575,727

     award amount
   • 5R01CA227830-06Department: NIH department code

     Targeting the Unfolded Protein Response in Leukemia Biology and Chemotherapy Resistance
     $347,976

     award amount

10. Rosen, David A.

    Leads 2 awards · $902,248

    • 1R01AI175038-01A1Department: NIH department code

      Protective immunity elicited by distinct polysaccharide antigens of classical and hypervirulent Klebsiella
      $668,998

      award amount
    • 1R21AI166090-01A1Department: NIH department code

      Immune recognition of Klebsiella pneumoniae O2v1 and O2v2 O-antigen subtypes
      $233,250

      award amount

11. Li, Fuhai

    Leads 2 awards · $811,285

    • 1R21AG078799-01A1Department: NIH department code

      AI models of multi-omic data integration for ming longevity core signaling pathways
      $460,659

      award amount
    • 1R01LM013902-01A1Department: NIH department code

      Modeling and targeting tumor-immune signaling interactions in tumor microenvironment
      $350,626

      award amount

12. Dharnidharka, Vikas R.

    Leads 1 award · $796,163

    • 5P50DK133943-02Department: NIH department code

      Pediatric Kidney Single Cell Atlas Project
      $796,163

      award amount

13. Fritz, Stephanie Ann

    Leads 1 award · $779,570

    • 5R01AI163161-03Department: NIH department code

      Microbial Community Disruption Following Topical Antimicrobial Application in Staphylococcus aureus-Affected Households
      $779,570

      award amount

14. Silverman, Gary Arthur

    Leads 2 awards · $760,739

    • 2K12HD076224-11Department: NIH department code

      Child Health Research Center
      $444,469

      award amount
    • 2T32HD043010-21Department: NIH department code

      Training of the Pediatric Physician-Scientist
      $316,270

      award amount

15. Cooper, Jonathan D

    Leads 2 awards · $758,132

    • 5R01NS124655-02Department: NIH department code

      Characterizing and testing the efficacy of AAV-mediated gene therapy in a sheep model of CLN1 disease.
      $521,882

      award amount
    • 5R21NS126907-02Department: NIH department code

      Defining and treating peripheral nervous system dysfunction in Cln1 disease
      $236,250

      award amount

16. Bednarski, Jeffrey J

    Leads 2 awards · $742,397

    • 5R01AI173077-02Department: NIH department code

      RAG-mediated DNA Damage Responses in Immune Development and Function
      $508,896

      award amount
    • 5R21AI166259-02Department: NIH department code

      MYSM1-dependent DNA damage responses in early B cell development
      $233,501

      award amount

17. Holtz, Lori R

    Leads 2 awards · $698,723

    • 5R01DK122029-04Department: NIH department code

      Role of Environmental Exposures on the Infant Gut Bacterial Microbiome and Virome
      $463,973

      award amount
    • 1R21AI171362-01A1Department: NIH department code

      Propagation and Characterization of Phage Related to Human Growth
      $234,750

      award amount

18. Bark, David

    Leads 2 awards · $624,763

    • 5R01HL164424-02Department: NIH department code

      Impact of turbulence on blood in mechanical circulatory support
      $421,522

      award amount
    • 1R21EB034579-01Department: NIH department code

      Paper-based high shear hemostatic analytical device
      $203,241

      award amount

19. Perlmutter, David H

    Leads 1 award · $623,637

    • 5R01DK131215-02Department: NIH department code

      Novel therapies that target mitochondrial dysfunction for treatment of a1-antitrypsin deficiency liver disease
      $623,637

      award amount

20. Fields, Melanie Erin

    Leads 1 award · $568,769

    • 5R01HL157188-03Department: NIH department code

      The Impact of Cerebral Metabolic Stress on the Development of the Structural and Functional Connectome in Pediatric Sickle Cell Anemia
      $568,769

      award amount

21. Greer, Eric Lieberman

    Leads 1 award · $568,187

    • 1R01AG084739-01Department: NIH department code

      Ribosomal RNA Methylation Regulation of Longevity and Stress Resistance
      $568,187

      award amount

22. Li, Weikai

    Leads 1 award · $565,339

    • 5R01AI158500-02Department: NIH department code

      Defining the partner interaction network of the tetraspanin CD53 in regulating B cell trafficking
      $565,339

      award amount

23. Di Paola, Jorge A

    Leads 1 award · $561,860

    • 5R01HL139825-04Department: NIH department code

      Genomics of Megakaryocyte and Platelet Biology
      $561,860

      award amount

24. Wylie, Kristine M.

    Leads 1 award · $555,368

    • 5R01AI142135-05Department: NIH department code

      Metagenomic shotgun microbial sequencing in post-transplant lymphoproliferative disorders (PTLD-MSMS)
      $555,368

      award amount

25. Cooper, Megan Anne

    Leads 2 awards · $536,250

    • 2R56AI127752-06A1Department: NIH department code

      Metabolic Regulation of Natural Killer Cell Activation
      $300,000

      award amount
    • 5R21AI168957-02Department: NIH department code

      Genetic Mosaicism in Inborn Errors of Immunity
      $236,250

      award amount

26. Buchser, William J

    Leads 2 awards · $530,228

    • 1R01NS132057-01Department: NIH department code

      Cellular Phenotypes of Genetic Variants in Mucopolysaccharidosis
      $451,478

      award amount
    • 5R03NS127256-02Department: NIH department code

      Cellular phenotype of mucopolysaccharidosis II for studies of genomic variants
      $78,750

      award amount

27. Ernst, Linda M

    Leads 1 award · $529,546

    • 5R01HD103762-03Department: NIH department code

      Viral pathogenesis of chronic inflammatory lesions of the placenta
      $529,546

      award amount

28. Wambach, Jennifer

    Leads 1 award · $517,525

    • 5R01HL149853-04Department: NIH department code

      Functional Characterization of ABCA3 Genomic Variants
      $517,525

      award amount

29. Earl, Ashlee Miriam

    Leads 1 award · $507,802

    • 5R01DK126697-04Department: NIH department code

      Cellular and Molecular Basis of Sex Specificity in UTI Pathogenesis
      $507,802

      award amount

30. Morley, Sharon Celeste

    Leads 1 award · $470,785

    • 5R01AI139540-05Department: NIH department code

      Strength of TCR:self-pMHC interactions in the periphery instructs CD4+ T help cell responses
      $470,785

      award amount

31. Padmanabhan, Vasantha

    Leads 1 award · $469,337

    • 5R01HL139639-05Department: NIH department code

      Gestational Hyperandrogenism in Cardiovascular Programming
      $469,337

      award amount

32. McKay, Virginia R

    Leads 1 award · $468,237

    • 5R01HS026742-05Department: NIH department code

      De-Implementation of Unnecessary Surgical Antibiotic Prophylaxis in Children
      $468,237

      award amount

33. Newland, Jason

    Leads 1 award · $467,558

    • 5R01CA235615-05Department: NIH department code

      RCT to Evaluate an Implementation Strategy to Increase Optimal Use of HPV Vaccine in Primary Care
      $467,558

      award amount

34. Baldridge, Dustin M

    Leads 1 award · $466,500

    • 1DP1DA058706-01Department: NIH department code

      High-Throughput Functional Genomics of Variants in Genes Linked to Substance Use Disorders
      $466,500

      award amount

35. Xiao, Xunjun

    Leads 1 award · $451,088

    • 5R01DK128188-02Department: NIH department code

      Pathophysiology of Chronic Pancreatitis Associated with Misfolded PNLIP Risk Variants
      $451,088

      award amount

36. Lowe, Mark E.

    Leads 1 award · $430,727

    • 5R01DK124415-04Department: NIH department code

      Does Proteotoxicity Contribute to Chronic Pancreatitis in Murine Models of Human Carboxyl Ester Lipase (CEL) Genetic Risk Variants?
      $430,727

      award amount

37. Hruska, Keith A

    Leads 1 award · $425,874

    • 5R01DK127186-03Department: NIH department code

      Novel Advances in the Pathophysiology and Treatment of the CKD-MBD
      $425,874

      award amount

38. Tarr, Phillip I

    Leads 1 award · $406,632

    • 2T32DK077653-31A1Department: NIH department code

      Pediatric Gastroenterology Research Training Program
      $406,632

      award amount

39. Hunstad, David

    Leads 1 award · $393,750

    • 5R01AI158418-03Department: NIH department code

      Novel Type 1 Pilus Receptors in Pyelonephritis and Recurrent UTI
      $393,750

      award amount

40. Magee, Jeffrey Alan

    Leads 1 award · $393,750

    • 5R01HL152180-04Department: NIH department code

      The role of Kmt2c/MLL3 in hematopoietic stem cell self-renewal, commitment and exhaustion
      $393,750

      award amount

41. Clemens, Regina

    Leads 1 award · $392,084

    • 5R01AI166793-02Department: NIH department code

      Membrane potential and Calcium Signaling in Neutrophil Development and Inflammation
      $392,084

      award amount

42. Schuettpelz, Laura G.

    Leads 1 award · $391,250

    • 2R01HL134896-06A1Department: NIH department code

      Protection of stressed hematopoietic stem cells by the tetraspanin family member CD53
      $391,250

      award amount

43. Rubin, Joshua B

    Leads 1 award · $366,581

    • 5R01CA174737-09Department: NIH department code

      Molecular basis for the impact of sex on brain tumorigenesis
      $366,581

      award amount

44. Janowski, Andrew Bok Seng

    Leads 1 award · $233,250

    • 1R21AI168955-01A1Department: NIH department code

      Characterization of a cerebral organoid model of astrovirus VA1 infection
      $233,250

      award amount

45. Di Paola, Jorge A

    Leads 1 award · $204,238

    • 5T32CA269116-02Department: NIH department code

      Pediatric Training Program Hematology and Oncology
      $204,238

      award amount

46. Bigley, Tarin M

    Leads 1 award · $198,640

    • 1K08AI168495-01A1Department: NIH department code

      Establishing the impact of roseolovirues on development of autoimmunity due to loss of central tolerance
      $198,640

      award amount

47. Orvedahl, Anthony W

    Leads 1 award · $167,181

    • 5K08AI144033-04Department: NIH department code

      Role of Autophagy in Regulating Cytokine-Induced Macrophage Cell Death and Systemic Inflammatory Responses
      $167,181

      award amount

48. Woo, Kelvin

    Leads 1 award · $165,141

    • 5K08HL165108-02Department: NIH department code

      The protective role of fibroblast growth factor signaling in hypoxia-induced pulmonary hypertension
      $165,141

      award amount

49. Schwartz, Drew Joel

    Leads 1 award · $163,524

    • 5K08AI159384-03Department: NIH department code

      Antibiotic disruption of the gut microbiome and immune response in neonatal late-onset sepsis
      $163,524

      award amount

50. Liss, Kim Hung Ho

    Leads 1 award · $162,372

    • 1K08DK131255-01A1Department: NIH department code

      Role of Lipid Metabolism in Hepatic Ischemia Reperfusion Injury in Steatotic Livers
      $162,372

      award amount

51. Cooper, Megan Anne

    Leads 1 award · $161,742

    • 5T32AI106688-10Department: NIH department code

      Pediatric Infectious Diseases and Immunity Training Program
      $161,742

      award amount

52. Stone, Stephen Isaac

    Leads 1 award · $160,804

    • 5K08DK124574-03Department: NIH department code

      Using a Rare Disease Model to Explore the Role of FGF21 in Insulin Resistance
      $160,804

      award amount

53. Yomogida, Kentaro

    Leads 1 award · $160,735

    • 5K08DK128544-02Department: NIH department code

      Impact of Aiolos on intestinal intraepithelial lymphocytes
      $160,735

      award amount

54. Horani, Amjad

    Leads 1 award · $159,435

    • 5K08HL150223-04Department: NIH department code

      The Role of Dynein Motor Mutations in Motile Cilia Disease
      $159,435

      award amount

55. Rusconi, Brigida Agnese

    Leads 1 award · $135,422

    • 5K01DK125606-04Department: NIH department code

      S1P as regulator of neonatal mucosal immune development and injury
      $135,422

      award amount

56. Gilbert, Nicole Marie

    Leads 1 award · $117,000

    • 5R03DK132442-02Department: NIH department code

      Deciphering the source and consequences of Nur77 expression during E. coli rUTI in mice
      $117,000

      award amount

57. King, Allison A

    Leads 1 award · $109,455

    • 5K24HL148305-05Department: NIH department code

      (SCANS) Sickle Cell Anemia Neurodevelopmental Screening - Mentoring and Research in Patient Oriented Research
      $109,455

      award amount

58. Zhang, Yiming

    Leads 1 award · $47,694

    • 5F31DK131875-02Department: NIH department code

      Leveraging arginine catabolism to treat metabolic diseases
      $47,694

      award amount

59. Mendoza-Castrejon, Jonny

    Leads 1 award · $33,646

    • 1F31CA268923-01A1Department: NIH department code

      The Role of SKIDA1 in Acute Myeloid Leukemia Initiation and Maintenance
      $33,646

      award amount