GENIE Cohort v19.0-public

The AACR Project Genomics, Evidence, Neoplasia, Information, Exchange (GENIE) is a multi-phase, multi-year, international data-sharing project that aims to catalyze precision cancer medicine. The GENIE platform will integrate and link clinical-grade cancer genomic data with clinical outcome data for tens of thousands of cancer patients treated at multiple international institutions. The project fulfills an unmet need in oncology by providing the statistical power necessary to improve clinical decision-making, to identify novel therapeutic targets, to understand of patient response to therapy, and to design new biomarker-driven clinical trials. The project will also serve as a prototype for aggregating, harmonizing, and sharing clinical-grade, next-generation sequencing (NGS) data obtained during routine medical practice. The GENIE dataset is generated from data curated by multiple cancer centers. Each center prepares their data by uploading their files onto the Synapse platform. The data presented here includes only those patients under the age of 40 years old.