Simulated NGS read datasets for bacterial pathogenic potential prediction

<p>## Predicting pathogenic potentials from NGS reads: novel bacterial species</p> <p>This repository contains simulated Illumina&nbsp;read datasets for bacterial pathogenic potential prediction and associated metadata extracted from the IMG Database (https://img.jgi.doe.gov/). The reads are 250bp long and were simulated with Mason (https://www.seqan.de/apps/mason/) from genomes downloaded from NCBI. The training-validation-test split was done on the species level to ensure &quot;novelty&quot; of validation and test species. The training sets contain 10 million reads per class, validation sets - 1.25 million reads per class, and test sets - 1.25 million paired reads per class. Additional, imbalanced training sets contain 2.5 million &quot;nonpathogenic&quot; and 17.5 million &quot;pathogenic&quot; reads, keeping the mean covarage constant for all species. The temporal benchmark test set contains reads from 3 additional pathogenic species in the Pantoea genus.</p> <p>## Predicting pathogenic potentials from NGS reads: novel strains of known species</p> <p>The BacPaCS datasets contain reads simulated from the dataset compiled by Barash et al. (https://doi.org/10.1093/bioinformatics/bty928). It this case, the training-validation-test split was done on the strain&nbsp;level (so different strains of the same species may be present in all three sets).</p>