Action potential evoked dendritic calcium signals in the medial superior olive (MSO) during development

<p>Dataset underlying the analysis of dendritic calcium signals evoked by somatic action potentials in MSO neurons during development (postnatal day 10 - 60). The data includes recordings from Mongolian gerbils (<em>Meriones unguiculatus</em>) raised in a normal acoustic environment and in omnidirectional white noise.</p> <p><strong>Linked paper:</strong>&nbsp;Franzen DL, Gleiss SA, Kellner CJ, Kladisios N, Felmy F. Activity-Dependent Calcium Signaling in Neurons of the Medial Superior Olive during Late Postnatal Development. J Neurosci. 2020 Feb 19;40(8):1689&ndash;700.&nbsp;<a href="https://doi.org/10.1523/JNEUROSCI.1545-19.2020">https://doi.org/10.1523/JNEUROSCI.1545-19.2020</a>.</p> <p><strong>Files included:</strong></p> <ul> <li> <p>A folder entitiled&nbsp;<em>data</em>&nbsp;containing:</p> <ul> <li>The imaging files (<code>.nix</code>) (1 file per imaged neuron). NIX files contain the kymograph data extracted from a ROI in the raw images along with the metadata.&nbsp;The imaging kymographs and associated&nbsp;<code>.nix</code>&nbsp;files were created with the&nbsp;<a href="https://zenodo.org/record/2575542#.XiYdAS2ZNo4">CaManager: ImageJ Plugin For Ca&sup2;⁺ Imaging</a>.</li> <li>An&nbsp;<code>excludes.csv</code>&nbsp;file that contains cells/trials to be excluded (e.g. recording error, movement, difficulty in tracing)</li> <li>A&nbsp;<code>Megatable_C.csv</code>&nbsp;file containing the electrophysiological data corresponding to imaged cells</li> </ul> </li> <li> <p>A&nbsp;<code>.nix</code>&nbsp;intermediate analysis file for&nbsp;<em>default parameters</em></p> </li> <li> <p>A&nbsp;<code>.csv</code>&nbsp;file with the combined electrophysiological and imaging data for&nbsp;<em>default parameters</em></p> </li> <li> <p>Several&nbsp;<code>.xlsx</code>&nbsp;files with the single cell data in Figures 2C, 2D, 2F.</p> </li> </ul> <p><strong>Jupyter notebook:</strong></p> <p>The&nbsp;<a href="https://github.com/delwen/CaJupyter">CaJupyter</a>&nbsp;GitHub repository contains a Jupyter notebook with a step-by-step guide of the analysis. It also allows for further exploration of the data.</p> <p><strong>See also:</strong></p> <ul> <li> <p>The original analysis code (without adaptations for the Jupyter notebook and Python 3) can be found at&nbsp;<a href="https://zenodo.org/record/2575675#.Xi%E2%80%A6">CaAnalysis: Analysis Toolbox for Ca&sup2;⁺ Imaging</a>.</p> </li> <li> <p>More information on NIX can be found at this&nbsp;<a href="https://g-node.github.io/nix/">link</a>.</p> </li> </ul>