Figures S1-S7. SMR-HEIDI analysis results for 8q24.21 locus between BP and selected phenotypes.

<p><strong>Supplementary Figures S1-S7. </strong><strong>SMR-HEIDI analysis results for rs6651255 between BP and selected phenotypes.</strong></p> <p>This project contains the following figures:</p> <ul> <li> <p>Figure S1. SMR-HEIDI analysis results for rs6651255 between BP and LDH.</p> </li> <li> <p>Figure S2. SMR-HEIDI analysis results for rs6651255 between BP and <em>GSDMC</em> expression in skeletal muscle (GTEx v6).</p> </li> <li> <p>Figure S3. SMR-HEIDI analysis results for rs6651255 between BP and <em>FAM49B</em> expression in Brain anterior cingulate cortex BA24 (GTEx v6).</p> </li> <li> <p>Figure S4. SMR-HEIDI analysis results for rs6651255 between BP and <em>FAM49B</em> expression in CD8 cell line (CEDAR).</p> </li> <li> <p>Figure S5. SMR-HEIDI analysis results for rs6651255 between BP and heel bone mineral density (UKBB).</p> </li> <li> <p>Figure S6. SMR-HEIDI analysis results for rs6651255 between BP and disc problem phenotype (UKBB)</p> </li> <li> <p>Figure S7. SMR-HEIDI analysis results for rs6651255 between BP and height (UKBB).</p> </li> </ul> <p>&nbsp;</p> <p><strong>Figures legend:</strong></p> <p>Each figure consists of four parts (1 &ndash; top left; 2- top right; 3- bottom left; 4 &ndash; bottom right):</p> <ol> <li> <p>Regional association plots for GWAS-1 (in our case BP GWAS) and GWAS-2 (expression or complex trait). Blue triangles represent SNPs used to calculate HEIDI test. Crossed triangle is leading SNP for which SMR test was computed.</p> </li> <li> <p>Z-Z plot (GWAS-1 on y-axis and GWAS-2 on x-axis).</p> </li> <li> <p>Visualization of LD matrix for SNPs used in calculation of HEIDI test.</p> </li> <li> <p>Plot of SMR regression coefficient estimates. The plot visualizes the heterogeneity of SMR coefficient. Blue color represents SNPs used to calculate HEIDI test.</p> </li> </ol>