Optogenetic response of mouse and macaque retinal ganglion cells
<p>Data presented in "Towards optogenetic vision restoration with high resolution"<br> BioRxiv https://www.biorxiv.org/content/10.1101/470773v1, to appear in PLOS Computational Biology.<br> Please cite this paper if the data have been useful for you.</p> <p>Data contains multi-electrode array recordings of optogenetic response of retinal ganglion cells subject to checkerboard visual stimulation.<br> Mouse: blind rd1 mice (4-5 weeks old) with an AAV2 encoding ReaChR-mCitrine under a pan-neuronal hSyn promoter via intravitreal injections. <br> Macaque: retinal ganglion cells have been targeted with an AAV2 encoding a human codon optimized CatCh under a strong, RGC-specific promoter. Retinas were harvested three months after injection of the virus in the adult macaque retina.</p>
ShareScore
32/100
Overall dataset sharing score
Score breakdown
These five areas show where the dataset supports — or may limit — practical reuse.
- Stewardship
- 8
- Harmonization
- 4
- Access
- 16
- Reuse readiness
- 0
- Engagement
- 4