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Optogenetic response of mouse and macaque retinal ganglion cells

<p>Data presented in &quot;Towards optogenetic vision restoration with high resolution&quot;<br> BioRxiv https://www.biorxiv.org/content/10.1101/470773v1,&nbsp;to appear in PLOS Computational Biology.<br> Please cite this paper if the data have been useful for you.</p> <p>Data contains multi-electrode array recordings of optogenetic response of&nbsp;retinal ganglion cells subject to checkerboard visual stimulation.<br> Mouse: blind rd1 mice (4-5 weeks old) with an AAV2&nbsp; encoding ReaChR-mCitrine under a pan-neuronal hSyn promoter&nbsp;via intravitreal injections.&nbsp;<br> Macaque:&nbsp;retinal ganglion cells have been targeted with an AAV2 encoding&nbsp;a human codon optimized CatCh under a strong, RGC-specific promoter.&nbsp;Retinas were harvested three months after injection of the virus&nbsp;in the adult macaque retina.</p>

ShareScore

32/100

Overall dataset sharing score

Score breakdown

These five areas show where the dataset supports — or may limit — practical reuse.

Stewardship
8
Harmonization
4
Access
16
Reuse readiness
0
Engagement
4

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