Preexisting memory CD4 T cells in naïve individuals confer robust immunity upon vaccination

<p>Data set accompanying the publication &quot;Preexisting memory CD4 T cells in na&iuml;ve individuals confer robust immunity upon vaccination&quot;.</p> <p>In this study, we utilize high-throughput sequencing to profile the memory CD4 TCR&beta; repertoire and track vaccine-specific and epitope-specific TCR&beta; clonotypes following the&nbsp;de novo&nbsp;administration of hepatitis B&nbsp;(HepB)&nbsp;vaccine&nbsp;in healthy HepB-na&iuml;ve individuals.</p> <p>The data set is comprised out of the following parts:</p> <ul> <li>repTCRb: Folder containing CD4+ TCR repertoire data from volunteers. Some of these samples are also available in ImmuneAccess (https://clients.adaptivebiotech.com/pub/deneuter-2018-cmvserostatus).</li> <li>peptideTCRab: Folder containing peptide-specific or peptide-pool-specific TCR data</li> <li>df_all: Meta and FC data for samples and volunteers</li> <li>freqCD154: CD154-based group definitions</li> <li>groups.csv: Group definitions used for classes</li> </ul>