Supplementary information to the article by van Beijnum et al. "Integrating phenotypic search and phosphoproteomic profiling of active kinases for optimization of drug mixtures for RCC treatment"

<p>Supplementary information to the article &quot;Integrating phenotypic search and phosphoproteomic profiling of active kinases for optimization of drug mixtures for RCC treatment&quot;.</p> <p><strong>Judy R. van Beijnum¹, Andrea Weiss^{2, 3}, Robert H. Berndsen^1,2, Tse J. Wong¹, Louise C. Reckman¹, Sander R. Piersma^4,5, Marloes Zoetemelk^2,3, Richard de Haas^1,4,5, Olivier Dormond⁶, Axel Bex^7,8, Alexander A. Henneman^4,5, Connie R. Jimenez^4,5, Arjan W. Griffioen¹, Patrycja Nowak-Sliwinska^2,3,9*</strong></p> <p>&nbsp;</p> <p>¹&nbsp;&nbsp;&nbsp; Angiogenesis Laboratory, Department of Medical Oncology, Amsterdam UMC, Vrije Universiteit Amsterdam, Medical Oncology, Cancer Center Amsterdam, De Boelelaan 1117, Amsterdam, Netherlands;</p> <p>²&nbsp;&nbsp;&nbsp; Molecular Pharmacology Group, School of Pharmaceutical Sciences, University of Geneva, Geneva, Switzerland*;</p> <p>^{3&nbsp; &nbsp;}Institute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, Geneva, Switzerland</p> <p>^{4&nbsp;&nbsp;}Department of Medical Oncology, Amsterdam UMC, Vrije Universiteit Amsterdam, Medical Oncology, Cancer Center Amsterdam, De Boelelaan 1117, Amsterdam, Netherlands</p> <p>⁵&nbsp;&nbsp;&nbsp; OncoProteomics Laboratory, Cancer Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands</p> <p>⁶&nbsp;&nbsp;&nbsp; Department of Visceral surgery, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland^&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</p> <p>⁷&nbsp;&nbsp; Royal Free London NHS Foundation Trust, Renal Cancer Centre, UCL Division of Surgical and Interventional Science, London, UK</p> <p>⁸&nbsp;&nbsp; Netherlands Cancer Institute, Amsterdam, The Netherlands</p> <p>⁹&nbsp;Translational Research Centre in Oncohaematology, Geneva, Switzerland</p> <p>&nbsp;Correspondence: <a href="mailto:Patrycja.Nowak-Sliwinska@unige.ch">Patrycja.Nowak-Sliwinska@unige.ch</a></p>