zenodoopen
HAND2 Targets Define a Network of Transcriptional Regulators that Compartmentalize the Early Limb Bud Mesenchyme
<p>Highlights</p> <p>•</p> <p>ChIP-seq identifies the CRMs bound by endogenous HAND2 in embryos and limb buds</p> <p>•</p> <p>HAND2 controls key transcriptional regulators acting upstream of SHH in limb buds</p> <p>•</p> <p>These transcriptional circuits define proximal, anterior, and posterior identities</p> <p>•</p> <p>HAND2 establishes anterior and posterior compartments by regulating <em>Gli3</em> and <em>Tbx3</em></p>
ShareScore
32/100
Overall dataset sharing score
Score breakdown
These five areas show where the dataset supports — or may limit — practical reuse.
- Stewardship
- 4
- Harmonization
- 4
- Access
- 16
- Reuse readiness
- 8
- Engagement
- 0