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A dataset of human and Plasmodium falciparum genotypes in severe malaria cases from The Gambia and Kenya

<p>This data&nbsp;release contains human and <em>Plasmodium falciparum</em>&nbsp;malaria genotypes&nbsp;from the article:</p> <p><strong>Malaria protection due to sickle haemoglobin depends on parasite genotype</strong></p> <p>Gavin Band, Ellen M. Leffler, Muminatou Jallow, Fatoumatta Sisay-Joof, Carolyne<br> M. Ndila, Alexander W. Macharia, Christina Hubbart, Anna E. Jeffreys, Kate Rowlands, Thuy<br> Nguyen, S&oacute;nia Gon&ccedil;alves, Cristina V. Ariani, Jim Stalker, Richard D. Pearson, Roberto<br> Amato, Eleanor Drury, Giorgio Sirugo, Umberto d&#39;Alessandro, Kalifa A. Bojang, Kevin<br> Marsh, Norbert Peshu, Joseph W. Saelens, Mahamadou Diakit&eacute;, Steve M. Taylor10, David J.<br> Conway, Thomas N. Williams, Kirk A. Rockett, Dominic P. Kwiatkowski</p> <p>Nature (2021) doi:&nbsp;<a href="https://doi.org/10.1038/s41586-021-04288-3">10.1038/s41586-021-04288-3</a>&nbsp;<strong>bioRxiv link</strong>:&nbsp;<a href="http://doi.org/10.1101/2021.03.30.437659">doi.org/10.1101/2021.03.30.437659</a>.</p> <p>The release contains genotypes from human and&nbsp;<em>Plasmodium falciparum</em>&nbsp;genetic variants, genotyped using blood samples from 4,171 children ascertained with severe symptoms of malaria at the Royal Victoria Teaching Hospital (now the Edward Francis Small Teaching Hospital), The Gambia, and from the Kilifi District Hospital (now Kilifi County Hospital), Kenya in the period 1995-2009.</p> <p>An accompanying set of association test summary statistics has also been released on Zenodo (doi:&nbsp;<a href="https://doi.org/10.5281/zenodo.5722497">10.5281/zenodo.5722497</a>). &nbsp;Please see&nbsp;<a href="http://www.malariagen.net/resource/32">www.malariagen.net/resource/32</a> for full details of other resources associated with the above manuscript.</p> <p>&nbsp;</p>

ShareScore

44/100

Overall dataset sharing score

Score breakdown

These five areas show where the dataset supports — or may limit — practical reuse.

Stewardship
8
Harmonization
4
Access
16
Reuse readiness
8
Engagement
8

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