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broadinstitute/lincs-cell-painting: Full release of LINCS Cell Painting dataset

<p>Summary</p> <p>This release contains finalized profile and metadata information for the CellProfiler-derived features from the LINCS Cell Painting dataset.</p> <p>We assayed two batches of data and applied an image analysis pipeline using CellProfiler to segment cells and extract morphology features. Using the CellProfiler output, we applied an image-based profiling pipeline to process the morphology profiles into an analysis-ready form.</p> <p>In this repository, we provide the full image-based profiling pipeline we used to process the data, as well as most of the intermediate data.</p> <p>Data counts</p> <ul> <li>Two batches (&quot;2016_04_01_a549_48hr_batch1&quot; and &quot;2017_12_05_Batch2&quot;)</li> <li>159,717,488 unique cells total</li> </ul> <p>2016_04_01_a549_48hr_batch1</p> <ul> <li>52,223 profiles (batch corrected)</li> <li>10,752 unique perturbations</li> <li>1,571 unique compounds</li> <li>1 time point (48 hour)</li> <li>7 doses</li> <li>1 cell line (A549)</li> <li>110,012,425 unique cells</li> </ul> <p>2017_12_05_Batch2</p> <ul> <li>51,447 profiles (batch corrected)</li> <li>10,368 unique perturbations</li> <li>349 unique compounds</li> <li>3 time points (6 hour, 24 hour, 48 hour)</li> <li>6 doses</li> <li>3 cell lines (A549, MCF7, U2OS)</li> <li>49,705,063 unique cells</li> </ul>

ShareScore

36/100

Overall dataset sharing score

Score breakdown

These five areas show where the dataset supports — or may limit — practical reuse.

Stewardship
4
Harmonization
4
Access
12
Reuse readiness
8
Engagement
8