HMC_visualisation_and_source_data_SS_v1.0.2

<p>This is the the code and data for:</p> <p>"Rethinking a hybrid malaria chemoprevention delivery strategy for children in sub-perennial settings: a modelling study integrating age- and seasonally-targeted delivery"</p> <p>Swapnoleena Sen1,2, David Schellenberg3, Melissa A Penny4,5*</p> <p>1Swiss Tropical and Public Health Institute, Allschwil, Switzerland</p> <p>2University of Basel, Basel, Switzerland</p> <p>3London School of Hygiene and Tropical Medicine, London, United Kingdom</p> <p><span lang="EN-IN">4The Kids Research Institute Australia, Nedlands, WA, Australia</span></p> <p><span lang="EN-IN">5Centre for Child Health Research, The University of Western Australia, Crawley, WA, Australia</span></p> <p>*Correspondence to: Prof Melissa A Penny (<a href="mailto:melissa.penny@uwa.edu.au">melissa.penny@uwa.edu.au</a>)</p> <p>In this study, using a validated individual-based malaria model combined with pharmacological models of drug action (OpenMalaria), we examined the potential public health impact of a proposed hybrid malaria chemoprevention (HMC, for children 03-24 months), and an age-expanded HMC (referred as HMC+, for children 03-36 months), under different assumptions of drug sensitivity, coverage, and prevalence (5-70%).</p> <p>The details of running OpenMalaria model, data generation and analysis (including R scripts used for preparing the source data files) for this study can be found in a separate "OpenMalaria_workflow_HMC_modeling_SS" repository (DOI: 10.5281/zenodo.13804293).&nbsp;</p> <p>Here the plotting functionalities are described. The repository is strcutured based on figures reported in the manuscript. Each figure has a folder as per its name that includes: 1) R code to plot figure 2) source data files and 3) one PNG and one PDF version of the figure.&nbsp;</p> <p>Please note: i) "dependencies.R" specifies all package information and dependencies in which the simulation, analysis scripts and plotting scripts are tested and stable.&nbsp;<br>ii) The R scripts rely on the folder structure and working directories used by the researchers. To replicate figures, you will need to adjust the file paths.</p>