Repetitive Transcranial Magnetic Stimulation of the human motor cortex modulates processing of heat pain sensation as assessed by the offset analgesia paradigm

<p>Heat pain threshold (HPT) values and Visual Analogue Scale (VAS) values recorded during a constant trial and an offset analgesia trial recorded at baseline and after active or sham&nbsp; repetitive Transcranial Magnetic Stimulation (rTMS).&nbsp; T1, T2 and T3 indicate different time intervals of OA trial, i.e., T1 = first 5 s interval of the individualized HPT, T2 = 5 s interval at a temperature 1 ˚C higher than T1, T3 = 20 s interval at the same temperature as T1. Constant trial included 30 s of a stimulus at HPT.</p>