Clinical datasets related DeNoPa olfaction, cerebrospinal fluid readouts and alpha-synuclein seeding aggregation assay

<p>These dataset files are associated with the manuscript:&nbsp;</p> <p>Mollenhauer B*, Li J*, Schade S, Weber S, Trenkwalder C, Concha-Marambio L, Tomlinson JJ, aSCENT-PD Investigators and Schlossmacher MG. <em>Persistent Hyposmia as Surrogate for alpha-Synuclein-Linked Brain Pathology.&nbsp;</em>Submitted 2023</p> <p>3 files:</p> <p>Data dictionary.csv</p> <p>Baseline_cut.csv</p> <p>Time_cut.csv</p> <p>The file "Data dictionary.csv" contains description of the two data files and the variables within.</p> <p>Clinical data used for this study is from the DeNoPa Cohort, led by Dr. Brit Mollenhauer, Department of Neurology, University of Goettingen, Kassel, Germany and the Paracelsus-Elena-Klinik. See references below for additional details.</p> <p>Mollenhauer B, Trautmann E, Sixel-D&ouml;ring F, Wicke T, Ebentheuer J, Schaumburg M, Lang E, Focke NK, Kumar KR, Lohmann K, Klein C, Schlossmacher MG, Kohnen R, Friede T, Trenkwalder C; DeNoPa Study Group. Nonmotor and diagnostic findings in subjects with de novo Parkinson disease of the DeNoPa cohort. Neurology. 2013 Oct 1;81(14):1226-34. doi: 10.1212/WNL.0b013e3182a6cbd5</p> <p>Concha-Marambio L, Weber S, Farris CM, Dakna M, Lang E, Wicke T, Ma Y, Starke M, Ebentheuer J, Sixel-D&ouml;ring F, Muntean ML, Schade S, Trenkwalder C, Soto C, Mollenhauer B. Accurate Detection of &alpha;-Synuclein Seeds in Cerebrospinal Fluid from Isolated Rapid Eye Movement Sleep Behavior Disorder and Patients with Parkinson's Disease in the DeNovo Parkinson (DeNoPa) Cohort. Mov Disord. 2023 Apr;38(4):567-578. doi: 10.1002/mds.29329</p>