GWAS Summary Statistics from "Sex and statin-related genetic associations at the PCSK9 gene locus – results of genome-wide association meta-analysis"

<p>GWAMA summary statistics of PCSK9 levels stratified by sex and statin useage in Europeans.</p> <p>When using this data, please cite:</p> <p>Pott, J., Kheirkhah, A., Gadin, J.R.&nbsp;<em>et al.</em> Sex and statin-related genetic associations at the <em>PCSK9</em> gene locus: results of genome-wide association meta-analysis. <em>Biol Sex Differ</em> <strong>15</strong>, 26 (2024). https://doi.org/10.1186/s13293-024-00602-6</p> <p>All txt files contain the following columns:</p> <ul> <li>markername (unique SNP ID)</li> <li>chr</li> <li>bp_hg19 (base position according to hg19)</li> <li>EA (effect allele)</li> <li>OA (other allele)</li> <li>EAF (effect allele frequency)</li> <li>info (minimal info score across all used studies)</li> <li>nSamples (sample size per SNP)</li> <li>nStudies (in case of double-stratified data: number of studies; in case of single-stratified data: 2, as it is a meta-analysis of the two double-stratified data sets)</li> <li>beta (effect estimate)</li> <li>SE (standard error)</li> <li>pval (p-value)</li> <li>I2 (SNP heterogeneity across studies)</li> <li>invalidAssoc (TRUE/FALSE flag if this variant was excluded in our analysis)</li> <li>reason4exclusion (reason why this SNP was excluded)</li> <li>phenotype (phenotyp setting)</li> </ul>