Fig. 5 in Characterization of undescribed melanoma inhibitors from Euphorbia mauritanica L. cultivated in Egypt targeting BRAF and MEK 1 kinases via in-silico study and ADME prediction

Fig. 5. (A) 2D binding mode, (B) 3D binding mode of Euphomauritanol A (1) in the active site of BRaf Kinase V600E (PDB ID: 4XV2) (C) 2D binding mode, and (D) 3D binding mode of euphomauritanophane A (3) in the active site of MEK 1 kinase (PDB ID: 4LMN).