Decoding the Brain Mosaic: Region and Cell Type-Specific Dysregulation Patterns in Stress and Psychiatric Disorders

<p>Supplementary Online Tables for the doctoral thesis "Decoding the Brain Mosaic: Region and Cell Type-Specific Dysregulation Patterns in Stress and Psychiatric Disorders" by Nathalie Gerstner.&nbsp;&nbsp;</p> <p>This repository includes complete lists of differentially expressed and differential hub genes, alongside the results of enrichment analysis for 8 brain regions examined in a mouse model for transcriptomic alterations following glucocorticoid stimulation (Online Tables 1-30). Additionally, the repository encompasses the complete results of differential expression and chromatin accessibility analyses across various cell types examined in postmortem brain tissue of the orbitofrontal cortex (Online Tables 31-37). These findings delineate the transcriptomic and epigenomic changes between psychiatric cases and controls, as well as between donors with high and low genetic risk for psychiatric disorders.</p> <p>The lists of all genes tested in the respective studies, not just the significant ones, can be found in the "GRactivation_MouseBrain_tables.zip" and the "SingleNuc_PostmortemBrain_Tables.zip" archives.</p> <p>&nbsp;</p>