Identification of clinically relevant T cell receptors for personalized T cell therapy using combinatorial algorithms

<p>Single-cell RNA (scRNA) and single-cell TCR (scTCR)-sequencing data data for patients number 11, 12 and 14 from the article " Identification of clinically relevant T-cell receptors for personlized T-cell therapy".&nbsp;</p> <p>Each compressed file contains two subfolders. One is for the scRNA-seq (GEX-sequencing) and the other for the scTCR-seq (VDJ-sequencing).&nbsp;</p> <p>In the original article, scRNA-seq and scTCR-seq were aligned to the GRCh38 reference genome using <em>cellranger count </em>(10X Genomics, version 3.0.1) and <em>vdj </em>(10X Genomics, version 3.1.0) respectively. The subsequent data processing was performed using Seurat library (V.4.3.0) on R Statistical Software (V.4.0.3).</p>