Figure 2 from: Hristov M, Sabit Z, Kirilov T, Bakalov D, Tzoneva R, Apostolova S, Georgieva I, Andreeva-Gateva P (2024) Effects of riboflavin on hyperalgesia and serum glutamine-to-glutamate ratio in rats with painful diabetic neuropathy. Pharmacia 71: 1-7. https://doi.org/10.3897/pharmacia.71.e120921

Figure 2 Effects of riboflavin on changes in pain threshold were investigated using the cold plate. Streptozotocin administration induced significant cold-induced hyperalgesia, alleviated notably by riboflavin in drinking water. Significant differences compared to the control group (Normal) are indicated as ***P < 0.001. Significant differences compared to the diabetic group (Diabetic) are indicated as #P < 0.05 and ###P < 0.001. n=8 animals per group.