Supplemental data for the publication: "Algal methylated compounds shorten the lag phase of Phaeobacter inhibens bacteria"

<p><strong>Data S1: </strong><em>P. inhibens </em>feature table (genes) with results from co-cultivation RNA-sequencing run. The dataset includes bacterial gene accession numbers, functional annotations, transcript abundances (TPM normalized read counts) and results of DESeq2 differential gene expression analysis. (Fig. 1, figs. S1A, S3-S4, tables S1-S2).&nbsp;</p> <p><strong>Data S2: </strong><em>P. inhibens </em>feature table (genes) with results from lag phase RNA-sequencing run. The dataset includes bacterial gene accession numbers, functional annotations, transcript abundances (TPM normalized read counts) and results of DESeq2 differential gene expression analysis. (Fig. 4A, figs. S10-S13, tables S6-S7).&nbsp;</p> <p><strong>Data S3: </strong><em>Emiliania huxleyi </em>CCMP3266 sGenome gene annotation file version 2 (GFF3 format).</p> <p><strong>Data S4: </strong>Feature quantification obtained using Compound Discoverer. The table presents the output analysis using Compound Discoverer (v3.3) with a putative identification of metabolites. Each identified metabolite (each row) contains a sub-table under the + tab (on the left side) that specifies the feature quantification in each analyzed sample. Sample ID appears in the &ldquo;Study File ID&rdquo; column in each sub-table. Values in the columns &ldquo;Exchange Rate [%]: 0&rdquo; and &ldquo;Exchange Rate [%]: 1&rdquo; represent relative abundances of the molecules in their unlabeled form and with single ¹³C-label (M+1 isotopologue), respectively. Compounds marked with &ldquo;1&rdquo; in the &ldquo;Tags&rdquo; column were further validated using standards. The average M+1 isotope abundance [%] for <em>S</em>-Adenosylmethionine (SAM) and 5'-<em>S</em>-Methyl-5'-thioadenosine (MTA)&mdash;as reported in Fig. 4D&mdash;were calculated by averaging the values in the &ldquo;Exchange Rate [%]: 1&rdquo; column from samples supplemented with ¹³C-labeled and unlabeled DMSP, respectively. Detailed information regarding the isotope abundances of SAM and MTA can be found in the tab &ldquo;SAM and MTA isotope abundance&rdquo; in the table. In the tab &ldquo;Features Positive Mode&rdquo; samples F10, F12, F14, and F16 were supplemented with ¹³C-labeled DMSP and samples F2, F4, F6, F8 were supplemented with unlabeled DMSP. In the tab &ldquo;Features Negative Mode&rdquo; samples F2, F3, F4, and F5 were supplemented with ¹³C-labeled DMSP and samples F10, F11, F12, F13 were supplemented with unlabeled DMSP.</p>