TCGA Chemotherapy Response Dataset

<p>Dataset&nbsp;on chemotherapeutic drug&nbsp;responses in TCGA cancer patients, cross-referenced for a hit in TCIA.at database, consisting of clinical (TCGA), cancer tissue gene-expression (TCGA) and tumor-immunome&nbsp;(TCIA) features. The dataset consists of 5 common chemotherapy agents, 3 CRC agents (FOLFOX, 5FU, Oxaliplatin) and 2 Lung agents (Carboplatin, Cisplatin). FOLFOX as a combinational therapy or regimen, was compiled from timings of monotherapies given to patients and as such is a novel dataset derived from TCGA data. FOLFOX dataset is primarily firstline treatment, while other drugs are not to be interpreted as firstline treatments. Drug&nbsp;datasets are individually available in own CSV files.</p> <p><strong>Citation</strong><br> Dalibor Hrg, Balthasar Huber, Lukas A. Huber. (2020). TCGA Chemotherapy Response Dataset. Zenodo.&nbsp;<a href="http://doi.org/10.5281/zenodo.3719291">http://doi.org/10.5281/zenodo.3719291</a></p> <p>The results here are in whole or part based upon data generated by the TCGA Research Network:&nbsp;<a href="https://www.cancer.gov/about-nci/organization/ccg/research/structural-genomics/tcga">https://www.cancer.gov/tcga</a>.</p> <p><strong>License&nbsp;</strong><br> CC BY-SA 4.0 International&nbsp;<a href="https://creativecommons.org/licenses/by-sa/4.0">https://creativecommons.org/licenses/by-sa/4.0</a>. Authors take no liability for any use of this data.</p> <p><strong>Contributions</strong><br> D. Hrg and B. Huber acknowledge major and equal work effort: data understanding, data science and dataset preparation (monotherapies and FOLFOX); L. A. Huber: help with dictionary of drug names and curration/cleaning of&nbsp;FOLFOX entries, clinical validation.</p> <p><strong>Contact &amp; Maintenance</strong><br> <a href="mailto:dalibor.hrg@gmail.com">dalibor.hrg@gmail.com</a><br> dalibor.hrg@i-med.ac.at</p>