Summary statistics for association tests between human and Plasmodium falciparum genetic variants in 3,346 severe malaria cases from The Gambia and Kenya

<p>This dataset contains summary statistics for association tests between human and<br> <em>Plasmodium falciparum</em>&nbsp;malaria parasite genetic variants, using data from 3,346 severe malaria cases from The Gambia and Kenya. &nbsp;These results underlie the analysis described in our paper:</p> <p><strong>&quot;Malaria protection due to sickle haemoglobin depends on parasite genotype&quot;</strong></p> <p>Gavin Band, Ellen M. Leffler, Muminatou Jallow, Fatoumatta Sisay-Joof, Carolyne M. Ndila, Alexander W. Macharia, Christina Hubbart, Anna E. Jeffreys, Kate Rowlands, Thuy Nguyen, S&oacute;nia M. Gon&ccedil;alves, Cristina V. Ariani, Jim Stalker, Richard D. Pearson, Roberto Amato, Eleanor Drury, Giorgio Sirugo, Umberto d&#39;Alessandro, Kalifa A. Bojang, Kevin Marsh, Norbert Peshu, Joseph W. Saelens, Mahamadou Diakit&eacute;, Steve M. Taylor, David J. Conway, Thomas N. Williams, Kirk A. Rockett, Dominic P. Kwiatkowski</p> <p>Nature (2021) doi:&nbsp;<a href="https://doi.org/10.1038/s41586-021-04288-3">10.1038/s41586-021-04288-3</a>&nbsp;<strong>bioRxiv link</strong>::&nbsp;<a href="https://doi.org/10.1101/2021.03.30.437659">doi.org/10.1101/2021.03.30.437659</a><br> <br> The genotype data underlying&nbsp;these summary statistics has also been deposited on Zenodo<br> (<a href="https://zenodo.org/record/4973477">doi:10.5281/zenodo.4973477</a>). &nbsp;The <a href="https://www.well.ox.ac.uk/~gav/hptest)">HPTEST&nbsp;software</a>&nbsp;used to generate these results has also been&nbsp;deposited (<a href="https://doi.org/10.5281/zenodo.5685580">doi:10.5281/zenodo.5685580</a>). &nbsp;Please see the <a href="https://www.malariagen.net/resource/32">MalariaGEN website</a>&nbsp;for a full list of&nbsp;datasets which have been released with this manuscript.</p> <p><strong>Data contents.</strong></p> <p>The dataset consists of a single <a href="http://sqlite.org">sqlite database file</a>&nbsp;containing the results, and an accompanying README file in markdown and html format. &nbsp;Please see the README file for full details of the data contents.</p> <p>&nbsp;</p>