gnomAD SQLite database V2.1.1

<p>This package scales the huge gnomAD files (on average ~120G/chrom) to a SQLite database with a size of 34G for WGS v2.1.1 (261.942.336 variants) and 99G for WGS v3.1.1 (about 759.302.267 variants), and allows scientists to look for various variant annotations present in gnomAD (i.e. Allele Count, Depth, Minor Allele Frequency, etc. - <a href="https://github.com/KalinNonchev/gnomAD_DB/blob/master/gnomad_db/pkgdata/gnomad_columns.yaml">here</a>&nbsp;you can find all selected features given the genome version). (A query containing 300.000 variants takes ~40s.)</p> <p>It extracts from a gnomAD vcf about 23 variant annotations. You can find further infromation about the exact fields&nbsp;<a href="https://github.com/KalinNonchev/gnomAD_DB/blob/master/gnomad_db/pkgdata/gnomad_columns.yaml">here</a>.</p> <p>gnomAD SQLite database V2.1.1</p>