BigWig files for FAIRE-seq data

<p><span>Butterfly wings exhibit a diversity of patterns which can vary between forewings and hindwings and spatially across the same wing. Regulation of morphological variation involves changes in how genes are expressed across different spatial scales which is driven by chromatin dynamics during development. How patterns of chromatin dynamics correspond to morphological variation remains unclear. Here we compared the chromatin landscape between forewings and hindwings and also across the proximal and distal regions of the hindwings in two butterfly species, <i>Bicyclus anynana </i>and<i> Danaus plexippus</i>. We found that the chromatin profile varied significantly between the different wing regions, however, there was no clear correspondence between the chromatin profile and the wing patterns. In some cases, wing regions with different phenotypes shared the same chromatin profile whereas those with a similar phenotype had a different profile. We also found that in the forewing, open chromatin regions were AT rich whereas those in the hindwing were GC rich. GC content also varied between the proximal and hindwing regions. These differences in GC content were also reflected in the transcription factor binding motifs that were differentially enriched between the wings and wing regions. Our results suggest that the chromatin landscape varies between different wing tissues and even spatially within the same tissue with no clear correspondence to phenotype. These findings may be explained by differences in how Hox genes cooperate with other transcription factors that show preferences for specific GC content and function either as activators or repressors in different wings or wing regions.</span></p>