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OMEN data set: Tokheim pancancer data set with genome-wide interaction network

<p>OMEN is a Network-based Driver Gene Identification method that exploits&nbsp;Mutual Exclusivity.<br> This repository stores the data used in a pancancer experiment showcasing this method.</p> <p>It consists of</p> <p>- [tokheim_pancancer_somatic_CADD.pl]&nbsp;A file containing CADD probabilities for gene-patient pairs&nbsp;(derived from the pancancer data set in Tokheim, Collin J., et al. &quot;Evaluating the evaluation of cancer driver genes.&quot;&nbsp;<em>Proceedings of the National Academy of Sciences</em>&nbsp;113.50 (2016): 14330-14335.) formatted to be used by&nbsp;OMEN.<br> - [tokheim_pancancer_somatic_coverage_ranks.pl] A file containing gene coverage data (derived from the CADD data) formatted to be used by OMEN.<br> - [network.pl] A file containing a genome-wide interaction network consisting of&nbsp;high quality metabolic interactions from Recon X and literature curated interactions from Intact. Recon X and Intact data was acquired from Pathway Commons version 8.<br> The resulting network covers 7901 samples, and contains 15.694 nodes and 178.051 edges.</p>

ShareScore

36/100

Overall dataset sharing score

Score breakdown

These five areas show where the dataset supports — or may limit — practical reuse.

Stewardship
4
Harmonization
4
Access
16
Reuse readiness
8
Engagement
4