Extended Data Fig. 6 in Bat coronaviruses related to SARS-CoV-2 and infectious for human cells

Extended Data Fig. 6 | Estimationof RBD–hACE2 bindingenergy. Time series (leftcolumn) andviolinplots (rightcolumn) of the RBD–hACE2 binding energyestimatedusing ROSETTA (A) and FoldX (B). Intheviolinplots,the whitecirclecorresponds tothemedianvalue,theblackrectangleextendsfrom thefirsttothethirdquantiles,andthethinblacklinerepresentsthe 95% confidenceintervals.Theanalysisisperformedfor 9 different MDsimulations: 3 replicatesof the SARS-CoV-2 (shadesof green), BANAL-236 (shadesof red), and BANAL-52/103 (shadesofblue) RBD–hACE2 complexes.