Transcription events constructed by txrevise

<p>List of pre-computed transcription events constructed by txrevise. See the txrevise home page for more details:&nbsp;https://github.com/kauralasoo/txrevise.</p> <p>If you use txrevise in your research, please cite the following paper: <a href="https://doi.org/10.7554/eLife.41673">Alasoo, Kaur, et al. &quot;Genetic effects on promoter usage are highly context-specific and contribute to complex traits.&quot; Elife 8 (2019): e41673</a></p> <p>We have constructed two types of events. In the main event files we have masked the alternative internal exons in the promoter and 3&#39; end events (labeled upstream and downstream). This ensures that we can reliably distinguish promoter usage and 3&#39; end usage from alternative splicing, which are likely to be driven by distinct molecular mechanisms. The main annotation files are:</p> <ul> <li>Homo_sapiens.GRCh37.87.version_1.tar.gz&nbsp;</li> <li>Homo_sapiens.GRCh38.92.version_1.tar.gz&nbsp;</li> <li>Homo_sapiens.GRCh38.96.version_1.tar.gz</li> </ul> <p>We have also constructed an alternative set of &quot;raw&quot; annotation files where the alternative internal exons in promoter and 3&#39; end events have not masked. This maximises QTL discovery, because we can now also detect splicing event near promoters and 3 ends, but it comes at the expense that we are no longer able to distinguish between different molecular mechanisms. The raw annotation files are:</p> <ul> <li>Homo_sapiens.GRCh37.87.raw_events.version_1.tar.gz&nbsp;</li> <li>Homo_sapiens.GRCh38.92.raw_events.version_1.tar.gz&nbsp;</li> </ul>