Data set for "A neuronal mechanism for motivational control of behavior"

<p>Acting to achieve goals depends on the ability to motivate specific behaviors based on their predicted&nbsp;consequences given an individual&rsquo;s internal state. However, the underlying neuronal mechanisms that&nbsp;encode and maintain such specific motivational control of behavior are poorly understood. Here, we used&nbsp;Ca2+ imaging and optogenetic manipulations in the basolateral amygdala of freely moving mice&nbsp;performing non-cued, self-paced instrumental goal-directed actions to receive and consume rewards. We&nbsp;found that distinct neuronal activity patterns sequentially represent the entire action-consumption&nbsp;behavioral sequence. Whereas action-associated patterns integrated the identity, value, and expectancy&nbsp;of pursued goals, consumption-associated patterns reflected the identity and value of experienced&nbsp;outcomes. Thus, the interplay between these patterns allows the maintenance of specific motivational&nbsp;states necessary to adaptively direct behavior toward prospective rewards.</p>