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Results for blind docking Tocriscreen 2.0 compounds against AlphaFold2 structural modules of human and parasite proteins

<p>Docking (GNINA 1.0) of 1280 Tocriscreen 2.0 compounds against &gt;4000 AlphaFold structures from humans and the parasitic nematode&nbsp;<em>Brugia malayi</em>.&nbsp;</p> <p>Results are provided as Pickle objects or GZipped CSVs.</p> <p>Tuned machine learning models (random forest and XGBoost)&nbsp;are also included for classifying actives/decoys.</p>

ShareScore

36/100

Overall dataset sharing score

Score breakdown

These five areas show where the dataset supports — or may limit — practical reuse.

Stewardship
4
Harmonization
4
Access
20
Reuse readiness
8
Engagement
0